-
1
-
-
0033624575
-
The common PPARy Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
-
Altshuler D, Hirschhorn JN, Klanmmark M et al. The common PPARy Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 2000; 26: 76-80
-
(2000)
Nat Genet
, vol.26
, pp. 76-80
-
-
Altshuler, D.1
Hirschhorn, J.N.2
Klanmmark, M.3
-
2
-
-
0031667127
-
Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-y2 gene with obesity in two Caucasian populations
-
Beamer BA, Yen CJ, Andersen RE et al Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-y2 gene with obesity in two Caucasian populations. Diabetes 1998; 47:1806-1808
-
(1998)
Diabetes
, vol.47
, pp. 1806-1808
-
-
Beamer, B.A.1
Yen, C.J.2
Andersen, R.E.3
-
3
-
-
0031595923
-
A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
-
DOI 10.1038/3099
-
Deeb SS, Fajas L, Němoto M et al. A Prol2Ala substitution in PPARy2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat Genet 1998; 20: 284-287 (Pubitemid 28507675)
-
(1998)
Nature Genetics
, vol.20
, Issue.3
, pp. 284-287
-
-
Deeb, S.S.1
Fajas, L.2
Nemoto, M.3
Pihlajamaki, J.4
Mykkanen, L.5
Kuusisto, J.6
Laakso, M.7
Fujimoto, W.8
Auwerx, J.9
-
4
-
-
0032781890
-
Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated receptor-gamma2 (PPAR-gamma2): Divergent modulating effects on body mass index in obese and lean Caucasian men
-
Ek J, Urhammer SA, Serensen TI et al. Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated receptor-gamma2 (PPAR-gamma2): divergent modulating effects on body mass index in obese and lean Caucasian men. Diabetologia 1999; 42: 892-895
-
(1999)
Diabetologia
, vol.42
, pp. 892-895
-
-
Ek, J.1
Urhammer, S.A.2
Serensen, T.I.3
-
5
-
-
0347316400
-
Does peroxisome proliferatoractivated receptor gamma genotype (Pro12Ala) modify the association of physical activity and dietary fat with fasting insulin level?
-
Franks PW, Luan J, Browne PO et al. Does peroxisome proliferatoractivated receptor gamma genotype (Pro12Ala) modify the association of physical activity and dietary fat with fasting insulin level? Metabolism 2004; 53: 11-16
-
(2004)
Metabolism
, vol.53
, pp. 11-16
-
-
Franks, P.W.1
Luan, J.2
Browne, P.O.3
-
6
-
-
4243353569
-
Comment: Studies of the Prol 2Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort: homozygosity of the Ala allele confers a decreased risk of the insulin resistance syndrome
-
Frederiksen JL, Bradbaek K, Fenger M et al. Comment: studies of the Prol 2Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort: homozygosity of the Ala allele confers a decreased risk of the insulin resistance syndrome. J Clin Endocrinol Metab. 2002; 87: 3989-3992
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 3989-3992
-
-
Frederiksen, J.L.1
Bradbaek, K.2
Fenger, M.3
-
7
-
-
1642375634
-
Molecular determinants of human adipose tissue: Differences between visceral and subcutaneous compartments in obese women
-
DOI 10.1210/jc.2003-031507
-
Giusti V, Suter M, Verdumo C et al. Molecular determinants of human adipose tissue: differences between visceral and subcutaneous compartments in obese women. J Clin Endocricol Metab 2004; 89: 1379-1384 (Pubitemid 38368440)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.3
, pp. 1379-1384
-
-
Giusti, V.1
Suter, M.2
Verdumo, C.3
Gaillard, R.C.4
Burckhardt, P.5
Pralong, F.P.6
-
8
-
-
0036772369
-
Effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ-2 gene on adiposity, insulin sensitivity and lipid profile in the Spanish population
-
González Sánchez JL, Serrano Ríos M, Fernández Perez C et al. Effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma-2 gene on adiposity, insulin sensitivity and lipid profile in the Spanish population. Eur J Endocrinol. 2002; 147: 495-501 (Pubitemid 35238145)
-
(2002)
European Journal of Endocrinology
, vol.147
, Issue.4
, pp. 495-501
-
-
Gonzalez Sanchez, J.L.1
Serrano Rios, M.2
Fernandez Perez, C.3
Laakso, M.4
Martinez Larrad, M.T.5
-
9
-
-
0036964937
-
Insulin resistance, intra-abdominal fat, cardiovascular risk factors, and androgens in healthy young women with type 1 diabetes mellitus
-
DOI 10.1210/jc.87.3.1036
-
Greenfield JR, Samaras K, Chishalm DJ. Insulin resistance, intra-abdominal fat, cardiovascular risk factors, and androgens in healthy young women with type I diabetes mellitus. J Clin Endocrinol Metab. 2002; 87:1036-1040 (Pubitemid 36121061)
-
(2002)
Journal of Clinical Endocrinology and Metabolism
, vol.87
, Issue.3
, pp. 1036-1040
-
-
Greenfield, J.R.1
Samaras, K.2
Chisholm, D.J.3
-
10
-
-
0034728762
-
The Pro12Ala polymorphism in PPAR γ2 may confer resistance to type 2 diabetes
-
DOI 10.1006/bbrc.2000.2605
-
Hara K, Okada T, Tobe K et al. The Pro 12Ala polymorphism in PPARy2 may confer resistance to type 2 diabetes. Biochem Biophys Res Commun 2000; 271: 212-216 (Pubitemid 30444879)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.271
, Issue.1
, pp. 212-216
-
-
Hara, K.1
Okada, T.2
Tobe, K.3
Yasuda, K.4
Mori, Y.5
Kadowaki, H.6
Hagura, R.7
Akanuma, Y.8
Kimura, S.9
Ito, C.10
Kadowaki, T.11
-
12
-
-
0034456568
-
Quantitative insulin sensitivity check index: A simple, accurate method for assessing insulin sensitivity in humans
-
DOI 10.1210/jc.85.7.2402
-
Katz A, Nambi SS, Mather K et al. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 2000; 85: 2402-2410 (Pubitemid 32269192)
-
(2000)
Journal of Clinical Endocrinology and Metabolism
, vol.85
, Issue.7
, pp. 2402-2410
-
-
Katz, A.1
Nambi, S.S.2
Mather, K.3
Baron, A.D.4
Follmann, D.A.5
Sullivan, G.6
Quon, M.J.7
-
13
-
-
0033387971
-
Peroxisome proliferator-activated receptor gamma gene locus is related to body mass index and lipid values in healthy nonobese subjects
-
Knoblauch H, Busjahn A, Müller-Myhsok B et al. Peroxisome proliferator-activated receptor gamma gene locus is related to body mass index and lipid values in healthy nonobese subjects. Arterioscler Thromb Vase Biol 1999; 19: 2940-2944
-
(1999)
Arterioscler Thromb Vase Biol
, vol.19
, pp. 2940-2944
-
-
Knoblauch, H.1
Busjahn, A.2
Müller-Myhsok, B.3
-
14
-
-
0037683722
-
Effect of the Pro12Ala polymorphism in the peroxisome proliferator-activated receptor (PPAR) γ2 gene on the expression of PPARγ target genes in adipose tissue of massively obese subjects
-
DOI 10.1210/jc.2002-020603
-
Kalehmainen M, Uusitupa MI, Alhava E et al. Effect of the Pro12Ala polymorphism in the peroxisome proliferator-activated receptor (PPAR) gamma2 gene on the expression of PPARgamma target genes in adipose tissue of massively obese subjects. J Clin Endocrinol Metab 2003; 88: 1717-1722 (Pubitemid 36623394)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.4
, pp. 1717-1722
-
-
Kolehmainen, M.1
Uusitupa, M.I.J.2
Alhava, E.3
Laakso, M.4
Vidal, H.5
-
15
-
-
0141815640
-
Estrogen receptor alpha regulates expression of the orphan receptor small heterodimer partner
-
Lai K, Harnish DC, Evans MJ. Estrogen receptor alpha regulates expression of the orphan receptor small heterodimer partner. J Biol Chem 2003; 278: 36418-36429
-
(2003)
J Biol Chem
, vol.278
, pp. 36418-36429
-
-
Lai, K.1
Harnish, D.C.2
Evans, M.J.3
-
16
-
-
0035123646
-
Evidence for gene-nutrient interaction at the PPARγ locus
-
Luan J, Browne PO, Harding AH et al. Evidence for gene-nutrient interaction at the PPARgamma locus. Diabetes 2001 ; 50: 686-689 (Pubitemid 32195237)
-
(2001)
Diabetes
, vol.50
, Issue.3
, pp. 686-689
-
-
Luan, J.1
Browne, P.O.2
Harding, A.-H.3
Halsall, D.J.4
O'Rahilly, S.5
Chatterjee, V.K.K.6
Wareham, N.J.7
-
17
-
-
0033060302
-
Pro12Ala substitution in the peroxisome proliferator-activated receptor-y2 is not associated with type 2 diabetes
-
Mandni FP, Vaccaro O, Sabatino L et al. Pro12Ala substitution in the peroxisome proliferator-activated receptor-y2 is not associated with type 2 diabetes. Diabetes 1998; 48: 1466-1468
-
(1998)
Diabetes
, vol.48
, pp. 1466-1468
-
-
Mandni, F.P.1
Vaccaro, O.2
Sabatino, L.3
-
18
-
-
0142209179
-
Effect of the peroxisome proliferates activated receptor-γ gene Pro12Ala variant on body mass index: A meta-analysis
-
Masud S, Ye S. Effect of the peroxisome proliferator activated receptor-gamma gene Pro12Ala variant on body mass index: a meta-analysis. J Med Genet 2003; 40: 773-780 (Pubitemid 37311078)
-
(2003)
Journal of Medical Genetics
, vol.40
, Issue.10
, pp. 773-780
-
-
Masud, S.1
Ye, S.2
-
19
-
-
34547768729
-
Effects of a PPARy gene variant on obesity characteristics in Brazil
-
Mattevi VS, Zembrzuski VM, Hutz MH. Effects of a PPARy gene variant on obesity characteristics in Brazil. Braz J Med Biol Res 2007; 40: 927-932
-
(2007)
Braz J Med Biol Res
, vol.40
, pp. 927-932
-
-
Mattevi, V.S.1
Zembrzuski, V.M.2
Hutz, M.H.3
-
20
-
-
4744340732
-
Impact of genetic variation of PPARγ in humans
-
DOI 10.1016/j.ymgme.2004.08.014, PII S1096719204002239, ASHG 2004 Meeting Toronto
-
Meirhaeghe A, Amouyel P. Impact of genetic variation of PPAy gamma in humans. Mol Genet Metab 2004; 83: 93-102 (Pubitemid 39311284)
-
(2004)
Molecular Genetics and Metabolism
, vol.83
, Issue.1-2
, pp. 93-102
-
-
Meirhaeghe, A.1
Amouyel, P.2
-
21
-
-
0001491179
-
Impact of the Peroxisome Proliferator Activated Receptor γ2 Pro12Ala polymorphism on adiposity, lipids and non-insulin-dependent diabetes mellitus
-
Meirhaeghe A, Fajas L, Helbecque N et al. Impact of the peroxisome proliferator-activated receptor y2 Prol2Ala polymorphism on adiposity, lipids and non-insulin-dependent diabetes mellitus. Int J Obesity 2000; 24:195-199 (Pubitemid 30107568)
-
(2000)
International Journal of Obesity
, vol.24
, Issue.2
, pp. 195-199
-
-
Meirhaeghe, A.1
Fajas, L.2
Helbecque, N.3
Cottel, D.4
Auwerx, J.5
Deeb, S.S.6
Amouyel, P.7
-
23
-
-
0034745185
-
The Pro12 - >Ala substitution in PPAR-gamma is associated with resistance to development of diabetes in the general population: Possible involvement in impairment of insulin secretion in individuals with type 2 diabetes
-
Mori H, lkegami H, Kawaguchi Y et al. The Pro12 - >Ala substitution in PPAR-gamma is associated with resistance to development of diabetes in the general population: possible involvement in impairment of insulin secretion in individuals with type 2 diabetes. Diabetes 2001 ; 50: 891-894
-
(2001)
Diabetes
, vol.50
, pp. 891-894
-
-
Mori, H.1
Lkegami, H.2
Kawaguchi, Y.3
-
26
-
-
33748286941
-
Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mellitus and peripheral insulin sensitivity in a population with a high intake of oleic acid
-
Soriguer F, Morcillo S, Cardona F et al. Pro12Ala polymorphism of the PPARy2 gene is associated with type 2 diabetes mellitus and peripheral insulin sensitivity in a population with a high intake of oleic acid. J Nutr 2006; 136: 2325-2330 (Pubitemid 44329990)
-
(2006)
Journal of Nutrition
, vol.136
, Issue.9
, pp. 2325-2330
-
-
Soriguer, F.1
Morcillo, S.2
Cardona, F.3
Rojo-Martinez, G.4
Almaraz, M.D.L.C.5
Ruiz De Adana, M.D.L.S.6
Olveira, G.7
Tinahones, F.8
Esteva, I.9
-
27
-
-
33845472305
-
Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor γ with pre-diabetic phenotypes: Meta-analysis of 57 studies on nondiabetic individuals
-
DOI 10.2337/dc06-0513
-
Tonjes A, Scholz M, Loeffler M et al. Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with prediabetic phenotypes: meta-analysis of 57 studies on nondiabetic individuals. Diabetes Care 2006; 29: 2489-2497 (Pubitemid 44912258)
-
(2006)
Diabetes Care
, vol.29
, Issue.11
, pp. 2489-2497
-
-
Tonjes, A.1
Scholz, M.2
Loeffler, M.3
Stumvoll, M.4
-
28
-
-
0033304551
-
Two polymorphisms in the peroxisome proliferator-activated receptor-γ gene are associated with severe overweight among obese women
-
Valve R, Sivenius K, Miettinen R et al. Two polymorphisms in the peroxisome proliferator-activated receptor y gene are associated with severe overweight among obese women. J Clin Endocrinol Metab 1999; 84: 3708-3712 (Pubitemid 30645229)
-
(1999)
Journal of Clinical Endocrinology and Metabolism
, vol.84
, Issue.10
, pp. 3708-3712
-
-
Valve, R.1
Sivenius, K.2
Miettinen, R.3
Pihlajamaki, J.4
Rissanen, A.5
Deeb, S.S.6
Auwerx, J.7
Uusitupa, M.8
Laakso, M.9
-
29
-
-
0030977450
-
Peroxisome proliferator-activated receptor gene expression in human tissues: Effects of obesity, weight loss, and regulation by insulin and glucocorticoids
-
Vidal-Puig A, Considine R, Jimenez-Linan M et al. Peroxisome proliferator-activated receptor gene expression in human tissues: effects of obesity, weight loss, and regulation by insulin and glucocorticoids. J Clin Invest 1997; 99: 2416-2422 (Pubitemid 27227719)
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.10
, pp. 2416-2422
-
-
Vidal-Puig, A.J.1
Considine, R.V.2
Jimenez-Linan, M.3
Werman, A.4
Pories, W.J.5
Caro, J.F.6
Flier, J.S.7
-
30
-
-
0034504237
-
Subcutaneous and visceral adipose tissue: Their relation to the metabolic syndrome
-
Wajchenberg BL. Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. End Rev 2000; 21: 637-738
-
(2000)
End Rev
, vol.21
, pp. 637-738
-
-
Wajchenberg, B.L.1
-
31
-
-
0345164399
-
Molecular scanning of the human peroxisome proliferator activated receptor γ (hPPARγ) gene in diabetic Caucasians: Identification of a Pro12Ala PPARγ2 missense mutation
-
DOI 10.1006/bbrc.1997.7798
-
Yen CJ, Beamer BA, Negri C et al. Molecular scanning of the human peroxisome proliferator activated receptor gamma gene in diabetic Caucasians: identification of a Pro12Ala PPARy2 missense mutation. Biochem Biophys Res Commun 1997; 241: 270-274 (Pubitemid 28020091)
-
(1997)
Biochemical and Biophysical Research Communications
, vol.241
, Issue.2
, pp. 270-274
-
-
Chung-Jen, Y.1
Beamer, B.A.2
Negri, C.3
Silver, K.4
Brown, K.A.5
Yarnall, D.P.6
Burns, D.K.7
Roth, J.8
Shuldiner, A.R.9
-
32
-
-
33644830049
-
A new IDF worldwide definition of the metabolic syndrome: The rationale and the results
-
Zimmet P, Alberti G, Shaw J. A new IDF worldwide definition of the metabolic syndrome: the rationale and the results. Diabetes Voice 2005; 50: 31-33
-
(2005)
Diabetes Voice
, vol.50
, pp. 31-33
-
-
Zimmet, P.1
Alberti, G.2
Shaw, J.3
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