Kinetics and thermodynamics of interaction of coagulation factor VIII with a pathogenic human antibody

Molecular Immunology

Volumn 47, Issue 2-3, 2009, Pages 290-297

  Dimitrov, Jordan D ^a,b,c   Roumenina, Lubka T ^a,b,c   Andre, Sebastien ^a,b,c   Repesse, Yohann ^a,b,c   Atanasov, Boris P ^d   Jacquemin, Marc ^e   Saint Remy, Jean Marie ^e   Bayry, Jagadeesh ^a,b,c   Kaveri, Srinivas V ^a,b,c   Lacroix Desmazes, Sebastien ^a,b,c  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c INSERM   (France)

^d INSTITUTE OF ORGANIC CHEMISTRY   (Bulgaria)

^e UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Antibodies; Antibody antigen interactions; Coagulation factor VIII; Inhibitory antibodies; Kinetics; Thermodynamics Hemophilia

Indexed keywords

BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 8 ANTIBODY; BLOOD CLOTTING INHIBITOR; EPITOPE; PHOSPHOLIPID;

ANTIGEN ANTIBODY REACTION; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ELECTRICITY; HYDROPHOBICITY; IONIC STRENGTH; KINETICS; MOLECULAR RECOGNITION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; SOLVATION; SURFACE PLASMON RESONANCE; THERMODYNAMICS;

ANTIBODIES; FACTOR VIII; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; OSMOLAR CONCENTRATION; SALTS; THERMODYNAMICS;

EID: 70450223699     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.09.021     Document Type: Article

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