Specific targeted gene repair using single-stranded DNA oligonucleotides at an endogenous locus in mammalian cells uses homologous recombination

DNA Repair

Volumn 8, Issue 12, 2009, Pages 1424-1433

  McLachlan, Jennifer ^a   Fernandez, Serena ^a   Helleday, Thomas ^b,c   Bryant, Helen E ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b STOCKHOLM UNIVERSITY   (Sweden)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Gene repair; Homologous recombination; Single stranded DNA oligonucleotides

Indexed keywords

GENOMIC DNA; HYDROXYUREA; MESSENGER RNA; OLIGONUCLEOTIDE; RNA; SINGLE STRANDED DNA; THYMIDINE;

ANIMAL CELL; ARTICLE; CELL CYCLE; CONTROLLED STUDY; DNA REPAIR; EXCISION REPAIR; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE LOCUS; GENE MUTATION; GENE TARGETING; GENE THERAPY; HOMOLOGOUS RECOMBINATION; MAMMAL CELL; MISMATCH REPAIR; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ANIMALS; BASE SEQUENCE; CELL LINE; DNA REPAIR; DNA, SINGLE-STRANDED; GENETIC LOCI; MOLECULAR SEQUENCE DATA; MUTATION; OLIGONUCLEOTIDES; RECOMBINATION, GENETIC; S PHASE;

MAMMALIA;

EID: 70450223691     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2009.09.014     Document Type: Article

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