Single-strand DNA-mediated targeted mutagenesis of genomic DNA in early mouse embryos is stimulated by Rad51/54 and by Ku70/86 inhibition

Gene Therapy

Volumn 15, Issue 6, 2008, Pages 468-472

  Morozov, V ^a   Wawrousek, E F ^a  

^a NATIONAL EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CRYSTALLIN; GENOMIC DNA; KU ANTIGEN; RAD51 PROTEIN; RAD54 PROTEIN; SINGLE STRANDED DNA;

ARTICLE; CONTROLLED STUDY; DNA MODIFICATION; DNA REPAIR; EMBRYO; EMBRYO DEVELOPMENT; ENZYME INHIBITION; GENE TARGETING; HOMOLOGOUS RECOMBINATION; MOUSE; MUTATION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; SURVIVAL; WILD TYPE;

ANIMALS; ANTIBODIES; ANTIGENS, NUCLEAR; BETA-CRYSTALLINS; CLEAVAGE STAGE, OVUM; DNA, SINGLE-STRANDED; DNA-BINDING PROTEINS; FEMALE; GENE TARGETING; GENE THERAPY; GENOME; HUMANS; MICE; MICROINJECTIONS; MUTAGENESIS; POINT MUTATION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RAD51 RECOMBINASE;

ANIMALIA;

EID: 40249103200     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/sj.gt.3303088     Document Type: Article

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