-
1
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
The Huntington's Disease Collaborative Research Group
-
The Huntington's Disease Collaborative Research Group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72, 971-983
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
2
-
-
28644433087
-
Normal Huntingtin function: An alternative approach to Huntington's disease
-
Cattaneo, E., Zuccato, C. and Tartari, M. (2005) Normal Huntingtin function: an alternative approach to Huntington's disease. Nat. Rev. Neurosci. 6, 919-930
-
(2005)
Nat. Rev. Neurosci
, vol.6
, pp. 919-930
-
-
Cattaneo, E.1
Zuccato, C.2
Tartari, M.3
-
3
-
-
0027176364
-
The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease
-
Andrew, S.E., Goldberg, Y.P., Kremer, B., Telenius, H., Theilmann, J., Adam, S., Starr, E., Squitieri, F., Lin, B., Kalchman, M.A. et al. (1993) The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease. Nat. Genet. 4, 398-403
-
(1993)
Nat. Genet
, vol.4
, pp. 398-403
-
-
Andrew, S.E.1
Goldberg, Y.P.2
Kremer, B.3
Telenius, H.4
Theilmann, J.5
Adam, S.6
Starr, E.7
Squitieri, F.8
Lin, B.9
Kalchman, M.A.10
-
4
-
-
0027261537
-
Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease
-
Snell, R.G., MacMillan, J.C., Cheadle, J.P., Fenton, I., Lazarou, L.P., Davies, P., MacDonald, M.E., Gusella, J.F., Harper, P.S. and Shaw, D.J. (1993) Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease. Nat. Genet. 4, 393-397
-
(1993)
Nat. Genet
, vol.4
, pp. 393-397
-
-
Snell, R.G.1
MacMillan, J.C.2
Cheadle, J.P.3
Fenton, I.4
Lazarou, L.P.5
Davies, P.6
MacDonald, M.E.7
Gusella, J.F.8
Harper, P.S.9
Shaw, D.J.10
-
5
-
-
0030612119
-
2 receptor gene expression in the striatum in Huntington's disease
-
2 receptor gene expression in the striatum in Huntington's disease. Ann. Neurol. 42, 215-221
-
(1997)
Ann. Neurol
, vol.42
, pp. 215-221
-
-
Augood, S.J.1
Faull, R.L.2
Emson, P.C.3
-
6
-
-
0034702030
-
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease
-
Luthi-Carter, R., Strand, A., Peters, N.L., Solano, S.M., Hollingsworth, Z.R., Menon, A.S., Frey, A.S., Spektor, B.S., Penney, E.B., Schilling, G. et al. (2000) Decreased expression of striatal signaling genes in a mouse model of Huntington's disease. Hum. Mol. Genet. 9, 1259-1271
-
(2000)
Hum. Mol. Genet
, vol.9
, pp. 1259-1271
-
-
Luthi-Carter, R.1
Strand, A.2
Peters, N.L.3
Solano, S.M.4
Hollingsworth, Z.R.5
Menon, A.S.6
Frey, A.S.7
Spektor, B.S.8
Penney, E.B.9
Schilling, G.10
-
7
-
-
0037101837
-
Polyglutamine and transcription: Gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects
-
Luthi-Carter, R., Strand, A.D., Hanson, S.A., Kooperberg, C., Schilling, G., La Spada, A.R., Merry, D.E., Young, A.B., Ross, C.A., Borchelt, D.R. and Olson, J.M. (2002) Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects. Hum. Mol. Genet. 11, 1927-1937
-
(2002)
Hum. Mol. Genet
, vol.11
, pp. 1927-1937
-
-
Luthi-Carter, R.1
Strand, A.D.2
Hanson, S.A.3
Kooperberg, C.4
Schilling, G.5
La Spada, A.R.6
Merry, D.E.7
Young, A.B.8
Ross, C.A.9
Borchelt, D.R.10
Olson, J.M.11
-
8
-
-
33644783812
-
Regional and cellular gene expression changes in human Huntington's disease brain
-
Hodges, A., Strand, A.D., Aragaki, A.K., Kuhn, A., Sengstag, T., Hughes, G., Elliston, L.A., Hartog, C., Goldstein, D.R., Thu, D. et al. (2006) Regional and cellular gene expression changes in human Huntington's disease brain. Hum. Mol. Genet. 15, 965-977
-
(2006)
Hum. Mol. Genet
, vol.15
, pp. 965-977
-
-
Hodges, A.1
Strand, A.D.2
Aragaki, A.K.3
Kuhn, A.4
Sengstag, T.5
Hughes, G.6
Elliston, L.A.7
Hartog, C.8
Goldstein, D.R.9
Thu, D.10
-
9
-
-
34547839797
-
Mutant Huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant Huntingtin length or wild-type Huntingtin dosage
-
Kuhn, A., Goldstein, D.R., Hodges, A., Strand, A.D., Sengstag, T., Kooperberg, C., Becanovic, K., Pouladi, M.A., Sathasivam, K., Cha, J.H. et al. (2007) Mutant Huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant Huntingtin length or wild-type Huntingtin dosage. Hum. Mol. Genet. 16, 1845-1861
-
(2007)
Hum. Mol. Genet
, vol.16
, pp. 1845-1861
-
-
Kuhn, A.1
Goldstein, D.R.2
Hodges, A.3
Strand, A.D.4
Sengstag, T.5
Kooperberg, C.6
Becanovic, K.7
Pouladi, M.A.8
Sathasivam, K.9
Cha, J.H.10
-
10
-
-
34347364706
-
Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease
-
Zuccato, C., Belyaev, N., Conforti, P., Ooi, L., Tartari, M., Papadimou, E., MacDonald, M., Fossale, E., Zeitlin, S., Buckley, N. and Cattaneo, E. (2007) Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease. J. Neurosci. 27, 6972-6983
-
(2007)
J. Neurosci
, vol.27
, pp. 6972-6983
-
-
Zuccato, C.1
Belyaev, N.2
Conforti, P.3
Ooi, L.4
Tartari, M.5
Papadimou, E.6
MacDonald, M.7
Fossale, E.8
Zeitlin, S.9
Buckley, N.10
Cattaneo, E.11
-
11
-
-
54849422301
-
Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner
-
Benn, C.L., Sun, T., Sadri-Vakili, G., McFarland, K.N., DiRocco, D.P., Yohrling, G.J., Clark, T.W., Bouzou, B. and Cha, J.H. (2008) Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner. J. Neurosci. 28, 10720-10733
-
(2008)
J. Neurosci
, vol.28
, pp. 10720-10733
-
-
Benn, C.L.1
Sun, T.2
Sadri-Vakili, G.3
McFarland, K.N.4
DiRocco, D.P.5
Yohrling, G.J.6
Clark, T.W.7
Bouzou, B.8
Cha, J.H.9
-
12
-
-
71549114589
-
Analysis of the repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy of non-neuronal genes in peripheral lymphocytes from patients with Huntington's disease
-
doi:10.1111/j.1750-3639.2008.00249.x
-
Marullo, M., Valenza, M., Mariotti, C., Di Donato, S., Cattaneo, E. and Zuccato, C. (2008) Analysis of the repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy of non-neuronal genes in peripheral lymphocytes from patients with Huntington's disease. Brain Pathol., doi:10.1111/j.1750-3639.2008.00249.x
-
(2008)
Brain Pathol
-
-
Marullo, M.1
Valenza, M.2
Mariotti, C.3
Di Donato, S.4
Cattaneo, E.5
Zuccato, C.6
-
13
-
-
0035919701
-
Loss of Huntingtin-mediated BDNF gene transcription in Huntington's disease
-
Zuccato, C., Ciammola, A., Rigamonti, D., Leavitt, B.R., Goffredo, D., Conti, L., MacDonald, M.E., Friedlander, R.M., Silani, V., Hayden, M.R. et al. (2001) Loss of Huntingtin-mediated BDNF gene transcription in Huntington's disease. Science 293, 493-498
-
(2001)
Science
, vol.293
, pp. 493-498
-
-
Zuccato, C.1
Ciammola, A.2
Rigamonti, D.3
Leavitt, B.R.4
Goffredo, D.5
Conti, L.6
MacDonald, M.E.7
Friedlander, R.M.8
Silani, V.9
Hayden, M.R.10
-
14
-
-
0041353535
-
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
-
Zuccato, C., Tartari, M., Crotti, A., Goffredo, D., Valenza, M., Conti, L., Cataudella, T., Leavitt, B.R., Hayden, M.R., Timmusk, T. et al. (2003) Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes. Nat. Genet. 35, 76-83
-
(2003)
Nat. Genet
, vol.35
, pp. 76-83
-
-
Zuccato, C.1
Tartari, M.2
Crotti, A.3
Goffredo, D.4
Valenza, M.5
Conti, L.6
Cataudella, T.7
Leavitt, B.R.8
Hayden, M.R.9
Timmusk, T.10
-
15
-
-
0037150687
-
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease
-
Dunah, A.W., Jeong, H., Griffin, A., Kim, Y.M., Standaert, D.G., Hersch, S.M., Mouradian, M.M., Young, A.B., Tanese, N. and Krainc, D. (2002) Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease. Science 296, 2238-2243
-
(2002)
Science
, vol.296
, pp. 2238-2243
-
-
Dunah, A.W.1
Jeong, H.2
Griffin, A.3
Kim, Y.M.4
Standaert, D.G.5
Hersch, S.M.6
Mouradian, M.M.7
Young, A.B.8
Tanese, N.9
Krainc, D.10
-
16
-
-
33745200299
-
Sp1 is up-regulated in cellular and transgenic models of Huntington disease, and its reduction is neuroprotective
-
Qiu, Z., Norflus, F., Singh, B., Swindell, M.K., Buzescu, R., Bejarano, M., Chopra, R., Zucker, B., Benn, C.L., DiRocco, D.P. et al. (2006) Sp1 is up-regulated in cellular and transgenic models of Huntington disease, and its reduction is neuroprotective. J. Biol. Chem. 281, 16672-16680
-
(2006)
J. Biol. Chem
, vol.281
, pp. 16672-16680
-
-
Qiu, Z.1
Norflus, F.2
Singh, B.3
Swindell, M.K.4
Buzescu, R.5
Bejarano, M.6
Chopra, R.7
Zucker, B.8
Benn, C.L.9
DiRocco, D.P.10
-
17
-
-
12944263711
-
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
-
Steffan, J.S., Kazantsev, A., Spasic-Boskovic, O., Greenwald, M., Zhu, Y.Z., Gohler, H., Wanker, E.E., Bates, G.P., Housman, D.E. and Thompson, L.M. (2000) The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription. Proc. Natl. Acad. Sci. U.S.A. 97, 6763-6768
-
(2000)
Proc. Natl. Acad. Sci. U.S.A
, vol.97
, pp. 6763-6768
-
-
Steffan, J.S.1
Kazantsev, A.2
Spasic-Boskovic, O.3
Greenwald, M.4
Zhu, Y.Z.5
Gohler, H.6
Wanker, E.E.7
Bates, G.P.8
Housman, D.E.9
Thompson, L.M.10
-
18
-
-
39649092720
-
A microRNA-based gene dysregulation pathway in Huntington's disease
-
Johnson, R., Zuccato, C., Belyaev, N.D., Guest, D.J., Cattaneo, E. and Buckley, N.J. (2008) A microRNA-based gene dysregulation pathway in Huntington's disease. Neurobiol. Dis. 29, 438-445
-
(2008)
Neurobiol. Dis
, vol.29
, pp. 438-445
-
-
Johnson, R.1
Zuccato, C.2
Belyaev, N.D.3
Guest, D.J.4
Cattaneo, E.5
Buckley, N.J.6
-
19
-
-
58149375393
-
The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease
-
Packer, A.N., Xing, Y., Harper, S.Q., Jones, L. and Davidson, B.L. (2008) The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease. J. Neurosci. 28, 14341-14346
-
(2008)
J. Neurosci
, vol.28
, pp. 14341-14346
-
-
Packer, A.N.1
Xing, Y.2
Harper, S.Q.3
Jones, L.4
Davidson, B.L.5
-
20
-
-
70350142444
-
Gene dysregulation in Huntington's disease: REST, microRNAs and beyond
-
Johnson, R. and Buckley, N.J. (2009) Gene dysregulation in Huntington's disease: REST, microRNAs and beyond. Neuromol. Med. 11, 183-199
-
(2009)
Neuromol. Med
, vol.11
, pp. 183-199
-
-
Johnson, R.1
Buckley, N.J.2
-
21
-
-
0032519868
-
Neuronal expression of zinc finger transcription factor REST/NRSF/XBR gene
-
Palm, K., Belluardo, N., Metsis, M. and Timmusk, T. (1998) Neuronal expression of zinc finger transcription factor REST/NRSF/XBR gene. J. Neurosci. 18, 1280-1296
-
(1998)
J. Neurosci
, vol.18
, pp. 1280-1296
-
-
Palm, K.1
Belluardo, N.2
Metsis, M.3
Timmusk, T.4
-
22
-
-
0344441724
-
Interaction of the repressor element 1-silencing transcription factor (REST) with target genes
-
Wood, I.C., Belyaev, N.D., Bruce, A.W., Jones, C., Mistry, M., Roopra, A. and Buckley, N.J. (2003) Interaction of the repressor element 1-silencing transcription factor (REST) with target genes. J. Mol. Biol. 334, 863-874
-
(2003)
J. Mol. Biol
, vol.334
, pp. 863-874
-
-
Wood, I.C.1
Belyaev, N.D.2
Bruce, A.W.3
Jones, C.4
Mistry, M.5
Roopra, A.6
Buckley, N.J.7
-
23
-
-
0347052876
-
Distinct RE-1 silencing transcription factor-containing complexes interact with different target genes
-
Belyaev, N.D., Wood, I.C., Bruce, A.W., Street, M., Trinh, J.B. and Buckley, N.J. (2004) Distinct RE-1 silencing transcription factor-containing complexes interact with different target genes. J. Biol. Chem. 279, 556-561
-
(2004)
J. Biol. Chem
, vol.279
, pp. 556-561
-
-
Belyaev, N.D.1
Wood, I.C.2
Bruce, A.W.3
Street, M.4
Trinh, J.B.5
Buckley, N.J.6
-
24
-
-
54949103985
-
REST regulates distinct transcriptional networks in embryonic and neural stem cells
-
Johnson, R., Teh, C.H., Kunarso, G., Wong, K.Y., Srinivasan, G., Cooper, M.L., Volta, M., Chan, S.S., Lipovich, L., Pollard, S.M. et al. (2008) REST regulates distinct transcriptional networks in embryonic and neural stem cells. PLoS Biol. 6, e256
-
(2008)
PLoS Biol
, vol.6
-
-
Johnson, R.1
Teh, C.H.2
Kunarso, G.3
Wong, K.Y.4
Srinivasan, G.5
Cooper, M.L.6
Volta, M.7
Chan, S.S.8
Lipovich, L.9
Pollard, S.M.10
-
25
-
-
54949091162
-
Stem cells have different needs for REST
-
Hermanson, O. (2008) Stem cells have different needs for REST. PLoS Biol. 6, e271
-
(2008)
PLoS Biol
, vol.6
-
-
Hermanson, O.1
-
26
-
-
34250767817
-
Chromatin crosstalk in development and disease: Lessons from REST
-
Ooi, L. and Wood, I.C. (2007) Chromatin crosstalk in development and disease: lessons from REST. Nat. Rev. Genet. 8, 544-554
-
(2007)
Nat. Rev. Genet
, vol.8
, pp. 544-554
-
-
Ooi, L.1
Wood, I.C.2
-
27
-
-
0028934541
-
REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons
-
Chong, J.A., Tapia-Ramirez, J., Kim, S., Toledo-Arai, J.J., Zheng, Y., Boutros, M.C., Altshuller, Y.M., Frohman, M.A., Kraner, S.D. and Mandel, G. (1995) REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons. Cell 80, 949-957
-
(1995)
Cell
, vol.80
, pp. 949-957
-
-
Chong, J.A.1
Tapia-Ramirez, J.2
Kim, S.3
Toledo-Arai, J.J.4
Zheng, Y.5
Boutros, M.C.6
Altshuller, Y.M.7
Frohman, M.A.8
Kraner, S.D.9
Mandel, G.10
-
28
-
-
0028968802
-
The neuron-restrictive silencer factor (NRSF): A coordinate repressor of multiple neuron-specific genes
-
Schoenherr, C.J. and Anderson, D.J. (1995) The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes. Science 267, 1360-1363
-
(1995)
Science
, vol.267
, pp. 1360-1363
-
-
Schoenherr, C.J.1
Anderson, D.J.2
-
29
-
-
33847032960
-
The mammalian epigenome
-
Bernstein, B.E., Meissner, A. and Lander, E.S. (2007) The mammalian epigenome. Cell 128, 669-681
-
(2007)
Cell
, vol.128
, pp. 669-681
-
-
Bernstein, B.E.1
Meissner, A.2
Lander, E.S.3
-
30
-
-
33644853802
-
Histone modifications: Signalling receptors and potential elements of a heritable epigenetic code
-
Nightingale, K.P., O'Neill, L.P. and Turner, B.M. (2006) Histone modifications: signalling receptors and potential elements of a heritable epigenetic code. Curr. Opin. Genet. Dev. 16, 125-136
-
(2006)
Curr. Opin. Genet. Dev
, vol.16
, pp. 125-136
-
-
Nightingale, K.P.1
O'Neill, L.P.2
Turner, B.M.3
-
31
-
-
60849088861
-
Profiling RE1/REST-mediated histone modifications in the human genome
-
Zheng, D., Zhao, K. and Mehler, M.F. (2009) Profiling RE1/REST-mediated histone modifications in the human genome. Genome Biol. 10, R9
-
(2009)
Genome Biol
, vol.10
-
-
Zheng, D.1
Zhao, K.2
Mehler, M.F.3
-
32
-
-
0029796093
-
Identification of potential target genes for the neuron-restrictive silencer factor
-
Schoenherr, C.J., Paquette, A.J. and Anderson, D.J. (1996) Identification of potential target genes for the neuron-restrictive silencer factor. Proc. Natl. Acad. Sci. U.S.A. 93, 9881-9886
-
(1996)
Proc. Natl. Acad. Sci. U.S.A
, vol.93
, pp. 9881-9886
-
-
Schoenherr, C.J.1
Paquette, A.J.2
Anderson, D.J.3
-
33
-
-
3142764484
-
Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes
-
Bruce, A.W., Donaldson, I.J., Wood, I.C., Yerbury, S.A., Sadowski, M.I., Chapman, M., Gottgens, B. and Buckley, N.J. (2004) Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes. Proc. Natl. Acad. Sci. U.S.A. 101, 10458-10463
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 10458-10463
-
-
Bruce, A.W.1
Donaldson, I.J.2
Wood, I.C.3
Yerbury, S.A.4
Sadowski, M.I.5
Chapman, M.6
Gottgens, B.7
Buckley, N.J.8
-
34
-
-
66449114042
-
Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level
-
Bruce, A.W., Lopez-Contreras, A.J., Flicek, P., Down, T.A., Dhami, P., Dillon, S.C., Koch, C.M., Langford, C.F., Dunham, I., Andrews, R.M. and Vetrie, D. (2009) Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level. Genome Res. 19, 994-1005
-
(2009)
Genome Res
, vol.19
, pp. 994-1005
-
-
Bruce, A.W.1
Lopez-Contreras, A.J.2
Flicek, P.3
Down, T.A.4
Dhami, P.5
Dillon, S.C.6
Koch, C.M.7
Langford, C.F.8
Dunham, I.9
Andrews, R.M.10
Vetrie, D.11
-
35
-
-
33749389932
-
Comparative genomics modeling of the NRSF/REST repressor network: From single conserved sites to genome-wide repertoire
-
Mortazavi, A., Leeper Thompson, E.C., Garcia, S.T., Myers, R.M. and Wold, B. (2006) Comparative genomics modeling of the NRSF/REST repressor network: from single conserved sites to genome-wide repertoire. Genome Res. 16, 1208-1221
-
(2006)
Genome Res
, vol.16
, pp. 1208-1221
-
-
Mortazavi, A.1
Leeper Thompson, E.C.2
Garcia, S.T.3
Myers, R.M.4
Wold, B.5
-
36
-
-
34250815056
-
A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions
-
Otto, S.J., McCorkle, S.R., Hover, J., Conaco, C., Han, J.J., Impey, S., Yochum, G.S., Dunn, J.J., Goodman, R.H. and Mandel, G. (2007) A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions. J. Neurosci. 27, 6729-6739
-
(2007)
J. Neurosci
, vol.27
, pp. 6729-6739
-
-
Otto, S.J.1
McCorkle, S.R.2
Hover, J.3
Conaco, C.4
Han, J.J.5
Impey, S.6
Yochum, G.S.7
Dunn, J.J.8
Goodman, R.H.9
Mandel, G.10
-
37
-
-
33748526495
-
Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication
-
Johnson, R., Gamblin, R.J., Ooi, L., Bruce, A.W., Donaldson, I.J., Westhead, D.R., Wood, I.C., Jackson, R.M. and Buckley, N.J. (2006) Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication. Nucleic Acids Res. 34, 3862-3877
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 3862-3877
-
-
Johnson, R.1
Gamblin, R.J.2
Ooi, L.3
Bruce, A.W.4
Donaldson, I.J.5
Westhead, D.R.6
Wood, I.C.7
Jackson, R.M.8
Buckley, N.J.9
-
38
-
-
1842334441
-
Anterograde transport of brain-derived neurotrophic factor and its role in the brain
-
Altar, C.A., Cai, N., Bliven, T., Juhasz, M., Conner, J.M., Acheson, A.L., Lindsay, R.M. and Wiegand, S.J. (1997) Anterograde transport of brain-derived neurotrophic factor and its role in the brain. Nature 389, 856-860
-
(1997)
Nature
, vol.389
, pp. 856-860
-
-
Altar, C.A.1
Cai, N.2
Bliven, T.3
Juhasz, M.4
Conner, J.M.5
Acheson, A.L.6
Lindsay, R.M.7
Wiegand, S.J.8
-
39
-
-
58049197863
-
Huntingtin regulates RE1-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) nuclear trafficking indirectly through a complex with REST/NRSF-interacting LIM domain protein (RILP) and dynactin p150 Glued
-
Shimojo, M. (2008) Huntingtin regulates RE1-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) nuclear trafficking indirectly through a complex with REST/NRSF-interacting LIM domain protein (RILP) and dynactin p150 Glued. J. Biol. Chem. 283, 34880-34886
-
(2008)
J. Biol. Chem
, vol.283
, pp. 34880-34886
-
-
Shimojo, M.1
-
40
-
-
0032872817
-
A molecular investigation of true dominance in Huntington's disease
-
Narain, Y., Wyttenbach, A., Rankin, J., Furlong, R.A. and Rubinsztein, D.C. (1999) A molecular investigation of true dominance in Huntington's disease. J. Med. Genet. 36, 739-746
-
(1999)
J. Med. Genet
, vol.36
, pp. 739-746
-
-
Narain, Y.1
Wyttenbach, A.2
Rankin, J.3
Furlong, R.A.4
Rubinsztein, D.C.5
-
41
-
-
0037075624
-
Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease
-
Zeron, M.M., Hansson, O., Chen, N., Wellington, C.L., Leavitt, B.R., Brundin, P., Hayden, M.R. and Raymond, L.A. (2002) Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease. Neuron 33, 849-860
-
(2002)
Neuron
, vol.33
, pp. 849-860
-
-
Zeron, M.M.1
Hansson, O.2
Chen, N.3
Wellington, C.L.4
Leavitt, B.R.5
Brundin, P.6
Hayden, M.R.7
Raymond, L.A.8
-
42
-
-
29144460321
-
Expression of mutant Huntingtin in glial cells contributes to neuronal excitotoxicity
-
Shin, J.Y., Fang, Z.H., Yu, Z.X., Wang, C.E., Li, S.H. and Li, X.J. (2005) Expression of mutant Huntingtin in glial cells contributes to neuronal excitotoxicity. J. Cell Biol. 171, 1001-1012
-
(2005)
J. Cell Biol
, vol.171
, pp. 1001-1012
-
-
Shin, J.Y.1
Fang, Z.H.2
Yu, Z.X.3
Wang, C.E.4
Li, S.H.5
Li, X.J.6
-
43
-
-
0033757718
-
Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice
-
Dragatsis, I., Levine, M.S. and Zeitlin, S. (2000) Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice. Nat. Genet. 26, 300-306
-
(2000)
Nat. Genet
, vol.26
, pp. 300-306
-
-
Dragatsis, I.1
Levine, M.S.2
Zeitlin, S.3
-
44
-
-
35348877164
-
Transcriptional signatures in Huntington's disease
-
Cha, J.H. (2007) Transcriptional signatures in Huntington's disease. Prog. Neurobiol. 83, 228-248
-
(2007)
Prog. Neurobiol
, vol.83
, pp. 228-248
-
-
Cha, J.H.1
-
45
-
-
68849083063
-
Brain-derived neurotrophic factor in neurodegenerative diseases
-
Zuccato, C. and Cattaneo, E. (2009) Brain-derived neurotrophic factor in neurodegenerative diseases. Nat. Rev. Neurol. 5, 311-322
-
(2009)
Nat. Rev. Neurol
, vol.5
, pp. 311-322
-
-
Zuccato, C.1
Cattaneo, E.2
-
46
-
-
33751254116
-
The neuronal microRNA system
-
Kosik, K.S. (2006) The neuronal microRNA system. Nat. Rev. Neurosci. 7, 911-920
-
(2006)
Nat. Rev. Neurosci
, vol.7
, pp. 911-920
-
-
Kosik, K.S.1
-
47
-
-
40449124713
-
MicroRNA expression in the adult mouse central nervous system
-
Bak, M., Silahtaroglu, A., Moller, M., Christensen, M., Rath, M.F., Skryabin, B., Tommerup, N. and Kauppinen, S. (2008) MicroRNA expression in the adult mouse central nervous system. RNA 14, 432-444
-
(2008)
RNA
, vol.14
, pp. 432-444
-
-
Bak, M.1
Silahtaroglu, A.2
Moller, M.3
Christensen, M.4
Rath, M.F.5
Skryabin, B.6
Tommerup, N.7
Kauppinen, S.8
-
48
-
-
0141631876
-
A microRNA array reveals extensive regulation of microRNAs during brain development
-
Krichevsky, A.M., King, K.S., Donahue, C.P., Khrapko, K. and Kosik, K.S. (2003) A microRNA array reveals extensive regulation of microRNAs during brain development. RNA 9, 1274-1281
-
(2003)
RNA
, vol.9
, pp. 1274-1281
-
-
Krichevsky, A.M.1
King, K.S.2
Donahue, C.P.3
Khrapko, K.4
Kosik, K.S.5
-
49
-
-
33745480963
-
Specific microRNAs modulate embryonic stem cell-derived neurogenesis
-
Krichevsky, A.M., Sonntag, K.C., Isacson, O. and Kosik, K.S. (2006) Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells 24, 857-864
-
(2006)
Stem Cells
, vol.24
, pp. 857-864
-
-
Krichevsky, A.M.1
Sonntag, K.C.2
Isacson, O.3
Kosik, K.S.4
-
50
-
-
33749078547
-
MicroRNA pathways modulate polyglutamine-induced neurodegeneration
-
Bilen, J., Liu, N., Burnett, B.G., Pittman, R.N. and Bonini, N.M. (2006) MicroRNA pathways modulate polyglutamine-induced neurodegeneration. Mol. Cell 24, 157-163
-
(2006)
Mol. Cell
, vol.24
, pp. 157-163
-
-
Bilen, J.1
Liu, N.2
Burnett, B.G.3
Pittman, R.N.4
Bonini, N.M.5
-
51
-
-
49449091708
-
Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies
-
Savas, J.N., Makusky, A., Ottosen, S., Baillat, D., Then, F., Krainc, D., Shiekhattar, R., Markey, S.P. and Tanese, N. (2008) Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies. Proc. Natl. Acad. Sci. U.S.A. 105, 10820-10825
-
(2008)
Proc. Natl. Acad. Sci. U.S.A
, vol.105
, pp. 10820-10825
-
-
Savas, J.N.1
Makusky, A.2
Ottosen, S.3
Baillat, D.4
Then, F.5
Krainc, D.6
Shiekhattar, R.7
Markey, S.P.8
Tanese, N.9
-
52
-
-
33144481470
-
Reciprocal actions of REST and a microRNA promote neuronal identity
-
Conaco, C., Otto, S., Han, J.J. and Mandel, G. (2006) Reciprocal actions of REST and a microRNA promote neuronal identity. Proc. Natl. Acad. Sci. U.S.A. 103, 2422-2427
-
(2006)
Proc. Natl. Acad. Sci. U.S.A
, vol.103
, pp. 2422-2427
-
-
Conaco, C.1
Otto, S.2
Han, J.J.3
Mandel, G.4
-
53
-
-
33750432857
-
Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression
-
Wu, J. and Xie, X. (2006) Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression. Genome Biol. 7, R85
-
(2006)
Genome Biol
, vol.7
-
-
Wu, J.1
Xie, X.2
-
54
-
-
0030866538
-
Transgenic models of Huntington's disease
-
Bates, G.P., Mangiarini, L., Mahal, A. and Davies, S.W. (1997) Transgenic models of Huntington's disease. Hum. Mol. Genet. 6, 1633-1637
-
(1997)
Hum. Mol. Genet
, vol.6
, pp. 1633-1637
-
-
Bates, G.P.1
Mangiarini, L.2
Mahal, A.3
Davies, S.W.4
-
55
-
-
13944282215
-
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
-
Lim, L.P., Lau, N.C., Garrett-Engele, P., Grimson, A., Schelter, J.M., Castle, J., Bartel, D.P., Linsley, P.S. and Johnson, J.M. (2005) Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433, 769-773
-
(2005)
Nature
, vol.433
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
Grimson, A.4
Schelter, J.M.5
Castle, J.6
Bartel, D.P.7
Linsley, P.S.8
Johnson, J.M.9
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