메뉴 건너뛰기




Volumn 19, Issue 6, 2009, Pages 994-1005

Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level

Author keywords

[No Author keywords available]

Indexed keywords

DNA; REST PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 66449114042     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.089086.108     Document Type: Article
Times cited : (72)

References (53)
  • 1
    • 0031019331 scopus 로고    scopus 로고
    • Expression of neuronal traits in pancreatic beta cells. Implication of neuron-restrictive silencing factor/repressor element silencing transcription factor, a neuron-restrictive silencer
    • Atouf, F., Czernichow, P., and Scharfmann, R. 1997. Expression of neuronal traits in pancreatic beta cells. Implication of neuron-restrictive silencing factor/repressor element silencing transcription factor, a neuron-restrictive silencer. J. Biol. Chem. 272: 1929-1934.
    • (1997) J. Biol. Chem. , vol.272 , pp. 1929-1934
    • Atouf, F.1    Czernichow, P.2    Scharfmann, R.3
  • 3
    • 19344378337 scopus 로고    scopus 로고
    • REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis
    • DOI 10.1016/j.cell.2005.03.013, PII S0092867405002850
    • Ballas, N., Grunseich, C., Lu, D.D., Speh, J.C., and Mandel, G. 2005. REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell 121: 645-657. (Pubitemid 40720016)
    • (2005) Cell , vol.121 , Issue.4 , pp. 645-657
    • Ballas, N.1    Grunseich, C.2    Lu, D.D.3    Speh, J.C.4    Mandel, G.5
  • 5
    • 3142764484 scopus 로고    scopus 로고
    • Genome-wide analysis of repressor element 1 silencing transcription factor/neuronrestrictive silencing factor (REST/NRSF) target genes
    • Bruce, A.W., Donaldson, I.J., Wood, I.C., Yerbury, S.A., Sadowski, M.I., Chapman, M., Gottgens, B., and Buckley, N.J. 2004. Genome-wide analysis of repressor element 1 silencing transcription factor/neuronrestrictive silencing factor (REST/NRSF) target genes. Proc. Natl. Acad. Sci. 101: 10458-10463.
    • (2004) Proc. Natl. Acad. Sci. , vol.101 , pp. 10458-10463
    • Bruce, A.W.1    Donaldson, I.J.2    Wood, I.C.3    Yerbury, S.A.4    Sadowski, M.I.5    Chapman, M.6    Gottgens, B.7    Buckley, N.J.8
  • 6
    • 33748051735 scopus 로고    scopus 로고
    • The transcriptional repressor REST is a critical regulator of the neurosecretory phenotype
    • DOI 10.1111/j.1471-4159.2006.04010.x
    • Bruce, A.W., Krejci, A., Ooi, L., Deuchars, J., Wood, I.C., Dolezal, V., and Buckley, N.J. 2006. The transcriptional repressor REST is a critical regulator of the neurosecretory phenotype. J. Neurochem. 98: 1828-1840. (Pubitemid 44298248)
    • (2006) Journal of Neurochemistry , vol.98 , Issue.6 , pp. 1828-1840
    • Bruce, A.W.1    Krejci, A.2    Ooi, L.3    Deuchars, J.4    Wood, I.C.5    Dolezal, V.6    Buckley, N.J.7
  • 9
    • 0031694917 scopus 로고    scopus 로고
    • NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis
    • Chen, Z.F., Paquette, A.J., and Anderson, D.J. 1998. NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis. Nat. Genet. 20: 136-142.
    • (1998) Nat. Genet. , vol.20 , pp. 136-142
    • Chen, Z.F.1    Paquette, A.J.2    Anderson, D.J.3
  • 10
    • 25844523898 scopus 로고    scopus 로고
    • Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation
    • DOI 10.1016/j.molcel.2005.08.030, PII S1097276505015947
    • Cheong, A., Bingham, A.J., Li, J., Kumar, B., Sukumar, P., Munsch, C., Buckley, N.J., Neylon, C.B., Porter, K.E., Beech, D.J., et al. 2005. Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation. Mol. Cell 20: 45-52. (Pubitemid 41396561)
    • (2005) Molecular Cell , vol.20 , Issue.1 , pp. 45-52
    • Cheong, A.1    Bingham, A.J.2    Li, J.3    Kumar, B.4    Sukumar, P.5    Munsch, C.6    Buckley, N.J.7    Neylon, C.B.8    Porter, K.E.9    Beech, D.J.10    Wood, I.C.11
  • 12
    • 24044505984 scopus 로고    scopus 로고
    • Transcriptional regulation: Cancer, neurons and the REST
    • Coulson, J.M. 2005. Transcriptional regulation: Cancer, neurons and the REST. Curr. Biol. 15: R665-R668.
    • (2005) Curr. Biol. , vol.15
    • Coulson, J.M.1
  • 13
    • 9244257298 scopus 로고    scopus 로고
    • Interacting models of cooperative gene regulation
    • Das, D., Banerjee, N., and Zhang, M.Q. 2004. Interacting models of cooperative gene regulation. Proc. Natl. Acad. Sci. 101: 16234-16239.
    • (2004) Proc. Natl. Acad. Sci. , vol.101 , pp. 16234-16239
    • Das, D.1    Banerjee, N.2    Zhang, M.Q.3
  • 15
    • 14944363825 scopus 로고    scopus 로고
    • NestedMICA: Sensitive inference of over-represented motifs in nucleic acid sequence
    • DOI 10.1093/nar/gki282
    • Down, T.A. and Hubbard, T.J. 2005. NestedMICA: Sensitive inference of over-represented motifs in nucleic acid sequence. Nucleic Acids Res. 33: 1445-1453. (Pubitemid 41418374)
    • (2005) Nucleic Acids Research , vol.33 , Issue.5 , pp. 1445-1453
    • Down, T.A.1    Hubbard, T.J.P.2
  • 16
    • 7444260846 scopus 로고    scopus 로고
    • The ENCODE (ENCyclopedia of DNA Elements) Project
    • The ENCODE Project Consortium
    • The ENCODE Project Consortium. 2004. The ENCODE (ENCyclopedia Of DNA Elements) Project. Science 306: 636-640.
    • (2004) Science , vol.306 , pp. 636-640
  • 17
    • 34250305146 scopus 로고    scopus 로고
    • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
    • The ENCODE Project Consortium
    • The ENCODE Project Consortium. 2007. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 447: 799-816.
    • (2007) Nature , vol.447 , pp. 799-816
  • 19
    • 15944374306 scopus 로고    scopus 로고
    • Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16
    • Fuller, G.N., Su, X., Price, R.E., Cohen, Z.R., Lang, F.F., Sawaya, R., and Majumder, S. 2005.Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16. Mol. Cancer Ther. 4: 343-349.
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 343-349
    • Fuller, G.N.1    Su, X.2    Price, R.E.3    Cohen, Z.R.4    Lang, F.F.5    Sawaya, R.6    Majumder, S.7
  • 21
    • 0036468361 scopus 로고    scopus 로고
    • Regulation of organogenesis by the Caenorhabditis elegans FoxA protein PHA-4
    • DOI 10.1126/science.1065175
    • Gaudet, J. and Mango, S.E. 2002. Regulation of organogenesis by the Caenorhabditis elegans FoxA protein PHA-4. Science 295: 821-825. (Pubitemid 34118356)
    • (2002) Science , vol.295 , Issue.5556 , pp. 821-825
    • Gaudet, J.1    Mango, S.E.2
  • 22
    • 34250369627 scopus 로고    scopus 로고
    • FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin
    • DOI 10.1101/gr.5533506
    • Giresi, P.G., Kim, J., McDaniell, R.M., Iyer, V.R., and Lieb, J.D. 2007. FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin. Genome Res. 17: 877-885. (Pubitemid 46919722)
    • (2007) Genome Research , vol.17 , Issue.6 , pp. 877-885
    • Giresi, P.G.1    Kim, J.2    McDaniell, R.M.3    Iyer, V.R.4    Lieb, J.D.5
  • 24
    • 0026736434 scopus 로고
    • The weak, fine-tuned binding of ubiquitous transcription factors to the Il-2 enhancer contributes to its T cell-restricted activity
    • Hentsch, B., Mouzaki, A., Pfeuffer, I., Rungger, D., and Serfling, E. 1992. The weak, fine-tuned binding of ubiquitous transcription factors to the Il-2 enhancer contributes to its T cell-restricted activity. Nucleic Acids Res. 20: 2657-2665.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 2657-2665
    • Hentsch, B.1    Mouzaki, A.2    Pfeuffer, I.3    Rungger, D.4    Serfling, E.5
  • 26
    • 19944367254 scopus 로고    scopus 로고
    • Defining the CREB regulon: A genome-wide analysis of transcription factor regulatory regions
    • DOI 10.1016/j.cell.2004.10.032, PII S0092867404011596
    • Impey, S., McCorkle, S.R., Cha-Molstad, H., Dwyer, J.M., Yochum, G.S., Boss, J.M., McWeeney, S., Dunn, J.J., Mandel, G., and Goodman, R.H. 2004. Defining the CREB regulon: A genome-wide analysis of transcription factor regulatory regions. Cell 119: 1041-1054. (Pubitemid 40037616)
    • (2004) Cell , vol.119 , Issue.7 , pp. 1041-1054
    • Impey, S.1    McCorkle, S.R.2    Cha-Molstad, H.3    Dwyer, J.M.4    Yochum, G.S.5    Boss, J.M.6    McWeeney, S.7    Dunn, J.J.8    Mandel, G.9    Goodman, R.H.10
  • 28
    • 34250159524 scopus 로고    scopus 로고
    • Genome-wide mapping of in vivo protein-DNA interactions
    • DOI 10.1126/science.1141319
    • Johnson, D.S., Mortazavi, A., Myers, R.M., and Wold, B. 2007. Genomewide mapping of in vivo protein-DNA interactions. Science 316: 1497-1502. (Pubitemid 46906620)
    • (2007) Science , vol.316 , Issue.5830 , pp. 1497-1502
    • Johnson, D.S.1    Mortazavi, A.2    Myers, R.M.3    Wold, B.4
  • 34
    • 0347362782 scopus 로고    scopus 로고
    • Critical role of the transcriptional repressor neuron-restrictive silencer factor in the specific control of connexin36 in insulin-producing cell lines
    • Martin, D., Tawadros, T., Meylan, L., Abderrahmani, A., Condorelli, D.F., Waeber, G., and Haefliger, J.A. 2003. Critical role of the transcriptional repressor neuron-restrictive silencer factor in the specific control of connexin36 in insulin-producing cell lines. J. Biol. Chem. 278: 53082-53089.
    • (2003) J. Biol. Chem. , vol.278 , pp. 53082-53089
    • Martin, D.1    Tawadros, T.2    Meylan, L.3    Abderrahmani, A.4    Condorelli, D.F.5    Waeber, G.6    Haefliger, J.A.7
  • 37
    • 33749389932 scopus 로고    scopus 로고
    • Comparative genomics modeling of the NRSF/REST repressor network: From single conserved sites to genome-wide repertoire
    • DOI 10.1101/gr.4997306
    • Mortazavi, A., Leeper Thompson, E.C., Garcia, S.T., Myers, R.M., and Wold, B. 2006. Comparative genomics modeling of the NRSF/REST repressor network: From single conserved sites to genome-wide repertoire. Genome Res. 16: 1208-1221. (Pubitemid 44506954)
    • (2006) Genome Research , vol.16 , Issue.10 , pp. 1208-1221
    • Mortazavi, A.1    Thompson, E.C.L.2    Garcia, S.T.3    Myers, R.M.4    Wold, B.5
  • 39
    • 0037154982 scopus 로고    scopus 로고
    • A unified theory of gene expression
    • DOI 10.1016/S0092-8674(02)00655-4
    • Orphanides, G. and Reinberg, D. 2002. A unified theory of gene expression. Cell 108: 439-451. (Pubitemid 34260870)
    • (2002) Cell , vol.108 , Issue.4 , pp. 439-451
    • Orphanides, G.1    Reinberg, D.2
  • 40
    • 34250815056 scopus 로고    scopus 로고
    • A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions
    • DOI 10.1523/JNEUROSCI.0091-07.2007
    • Otto, S.J., McCorkle, S.R., Hover, J., Conaco, C., Han, J.J., Impey, S., Yochum, G.S., Dunn, J.J., Goodman, R.H., and Mandel, G. 2007. A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions. J. Neurosci. 27: 6729-6739. (Pubitemid 46983428)
    • (2007) Journal of Neuroscience , vol.27 , Issue.25 , pp. 6729-6739
    • Otto, S.J.1    McCorkle, S.R.2    Hover, J.3    Conaco, C.4    Han, J.-J.5    Impey, S.6    Yochum, G.S.7    Dunn, J.J.8    Goodman, R.H.9    Mandel, G.10
  • 41
    • 0032519868 scopus 로고    scopus 로고
    • Neuronal expression of zinc finger transcription factor REST/NRSF/XBR gene
    • Palm, K., Belluardo, N., Metsis, M., and Timmusk, T.O 1998. Neuronal expression of zinc finger transcription factor REST/NRSF/XBR gene. J. Neurosci. 18: 1280-1296. (Pubitemid 28082414)
    • (1998) Journal of Neuroscience , vol.18 , Issue.4 , pp. 1280-1296
    • Palm, K.1    Belluardo, N.2    Metsis, M.3    Timmusk, T.4
  • 44
    • 33750488431 scopus 로고    scopus 로고
    • The genomic landscape of histone modifications in human T cells
    • Roh, T.Y., Cuddapah, S., Cui, K., and Zhao, K. 2006. The genomic landscape of histone modifications in human T cells. Proc. Natl. Acad. Sci. 103: 15782-15787.
    • (2006) Proc. Natl. Acad. Sci. , vol.103 , pp. 15782-15787
    • Roh, T.Y.1    Cuddapah, S.2    Cui, K.3    Zhao, K.4
  • 45
    • 2942631126 scopus 로고    scopus 로고
    • Localized domains of G9a-mediated histone methylation are required for silencing of neuronal genes
    • DOI 10.1016/j.molcel.2004.05.026, PII S109727650400303X
    • Roopra, A., Qazi, R., Schoenike, B., Daley, T.J., and Morrison, J.F. 2004. Localized domains of G9a-mediated histone methylation are required for silencing of neuronal genes. Mol. Cell 14: 727-738. (Pubitemid 38780847)
    • (2004) Molecular Cell , vol.14 , Issue.6 , pp. 727-738
    • Roopra, A.1    Qazi, R.2    Schoenike, B.3    Daley, T.J.4    Morrison, J.F.5
  • 46
    • 0028968802 scopus 로고
    • The neuron-restrictive silencer factor (NRSF): A coordinate repressor of multiple neuron-specific genes
    • Schoenherr, C.J. and Anderson, D.J. 1995. The neuron-restrictive silencer factor (NRSF): A coordinate repressor of multiple neuron-specific genes. Science 267: 1360-1363.
    • (1995) Science , vol.267 , pp. 1360-1363
    • Schoenherr, C.J.1    Anderson, D.J.2
  • 47
    • 0029796093 scopus 로고    scopus 로고
    • Identification of potential target genes for the neuron-restrictive silencer factor
    • Schoenherr, C.J., Paquette, A.J., and Anderson, D.J. 1996. Identification of potential target genes for the neuron-restrictive silencer factor. Proc. Natl. Acad. Sci. 93: 9881-9886.
    • (1996) Proc. Natl. Acad. Sci. , vol.93 , pp. 9881-9886
    • Schoenherr, C.J.1    Paquette, A.J.2    Anderson, D.J.3
  • 48
    • 0030020259 scopus 로고    scopus 로고
    • A zinc finger protein that represses transcription of the human MHC class II gene, DPA
    • Scholl, T., Stevens, M.B., Mahanta, S., and Strominger, J.L. 1996. A zinc finger protein that represses transcription of the human MHC class II gene, DPA. J. Immunol. 156: 1448-1457. (Pubitemid 26065855)
    • (1996) Journal of Immunology , vol.156 , Issue.4 , pp. 1448-1457
    • Scholl, T.1    Stevens, M.B.2    Mahanta, S.3    Strominger, J.L.4
  • 49
    • 0034072450 scopus 로고    scopus 로고
    • DNA binding sites: Representation and discovery
    • Stormo, G.D. 2000. DNA binding sites: Representation and discovery. Bioinformatics 16: 16-23. (Pubitemid 30204197)
    • (2000) Bioinformatics , vol.16 , Issue.1 , pp. 16-23
    • Stormo, G.D.1
  • 52
    • 33646844116 scopus 로고    scopus 로고
    • A clustering property of highly-degenerate transcription factor binding sites in the mammalian genome
    • DOI 10.1093/nar/gkl248
    • Zhang, C., Xuan, Z., Otto, S., Hover, J.R., McCorkle, S.R., Mandel, G., and Zhang, M.Q. 2006. A clustering property of highly-degenerate transcription factor binding sites in the mammalian genome. Nucleic Acids Res. 34: 2238-2246. (Pubitemid 43985662)
    • (2006) Nucleic Acids Research , vol.34 , Issue.8 , pp. 2238-2246
    • Zhang, C.1    Xuan, Z.2    Otto, S.3    Hover, J.R.4    McCorkle, S.R.5    Mandel, G.6    Zhang, M.Q.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.