Synthesis and anticancer activity of N-bis(trifluoromethyl)alkyl-N′-thiazolyl and N-bis(trifluoromethyl)alkyl-N′-benzothiazolyl ureas

European Journal of Medicinal Chemistry

Volumn 44, Issue 12, 2009, Pages 4944-4953

  Luzina, Elena L ^a   Popov, Anatoliy V ^a,b  

^a INSTITUTE OF PHYSIOLOGICALLY ACTIVE COMPOUNDS   (Russian Federation)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Anticancer activity; Fluorinated ureas; Synthesis

Indexed keywords

1 (1,1 BIS TRIFLUOROMETHYL PROPYL) 3 THIAZOL 2 YL UREA; 1 BENZOTHIAZOL 2 YL 3 (1,1 BIS TRIFLUOROMETHYL PROPYL) UREA; 1 BENZOTHIAZOL 2 YL 3 (2,2,2 TRIFLUORO 1 METHYL 1 TRIFLUOROMETHYL ETHYL) UREA; 1 BENZOTHIAZOL 2 YL 3 (2,2,2 TRIFLUORO 1 TRIFLUOROMETHYL ETHYL) UREA; 1 THIAZOL 2 YL 3 (2,2,2 TRIFLUORO 1 METHYL 1 TRIFLUOROMETHYLETHYL) UREA; 1 THIAZOL 2 YL 3 (2,2,2 TRIFLUORO 1 TRIFLUOROMETHYLETHYL) UREA; ANTINEOPLASTIC AGENT; N BIS(TRIFLUOROMETHYL)ALKYL N' BENZOTHIAZOLYL UREA; N BIS(TRIFLUOROMETHYL)ALKYL N' THIAZOLYL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CENTRAL NERVOUS SYSTEM TUMOR; DRUG SENSITIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY CANCER; LEUKEMIA; NATIONAL HEALTH ORGANIZATION; PROSTATE CANCER; UNITED STATES;

ANTINEOPLASTIC AGENTS; BENZOTHIAZOLES; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; HYDROCARBONS, FLUORINATED; MOLECULAR STRUCTURE; UREA;

EID: 70449704101     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.08.007     Document Type: Article

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