Mechanistic role of each metal ion in Streptomyces dinuclear aminopeptidase: Peptide hydrolysis and 7 × 1010-fold rate enhancement of phosphodiester hydrolysis

Journal of Inorganic Biochemistry

Volumn 104, Issue 1, 2010, Pages 19-29

  Ercan, Altan ^a   Tay, William M ^a   Grossman, Steven H ^a   Ming, Li June ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Aminopeptidase; Catalytic promiscuity; Dinuclear; Manganese; NMR; Streptomyces

Indexed keywords

AMINOPEPTIDASE; CADMIUM; COBALT; COBALT DERIVATIVE; MANGANESE; METAL DERIVATIVE; METAL ION; NICKEL; PEPTIDE; PHOSPHATE; PHOSPHONIC ACID ESTER; WATER; ZINC ION;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; HYDROGEN BOND; HYDROLYSIS; METAL BINDING; MOLECULAR DOCKING; PH; STREPTOMYCES GRISEUS; TEMPERATURE;

AMINOPEPTIDASES; BINDING SITES; COORDINATION COMPLEXES; FLUORIDES; HYDROLYSIS; IONS; KINETICS; METALS; NITROPHENOLS; PEPTIDES; STREPTOMYCES GRISEUS;

STREPTOMYCES; STREPTOMYCES GRISEUS;

EID: 70449637183     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2009.09.019     Document Type: Article

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