Purification and characterization of Pranlukast hydrolase from rat liver microsomes: The hydrolase is identical to carboxylesterase pI 6.2

Biological and Pharmaceutical Bulletin

Volumn 20, Issue 1, 1997, Pages 71-75

  Luan, Libiao ^a,b   Sugiyama, Tadashi ^c   Takai, Satomi ^b   Usami, Yoshiko ^b   Adachi, Tetsuo ^b   Katagiri, Yoshihiro ^c   Hirano, Kazuyuki ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^c GIFU UNIVERSITY HOSPITAL   (Japan)

Author keywords

carboxylesterase; pranlukast hydrolyzing enzyme; rat microsome

Indexed keywords

1 NAPHTHYL ACETATE; 4 NITROPHENYL PHOSPHATE; BENZYLSULFONYL FLUORIDE; CARBOXYLESTERASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROLASE; PRANLUKAST; PRODRUG;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG HYDROLYSIS; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME PURIFICATION; ENZYME SPECIFICITY; LIVER MICROSOME; MALE; NONHUMAN; RAT; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE;

EID: 0031013066     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.20.71     Document Type: Article

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