-
1
-
-
0027423419
-
Role of insulin-like growth factors in embryonic and postnatal growth
-
Baker J., Liu J.P., Robertson E.J., and Efstratiadis A. Role of insulin-like growth factors in embryonic and postnatal growth. Cell 75 (1993) 73-82
-
(1993)
Cell
, vol.75
, pp. 73-82
-
-
Baker, J.1
Liu, J.P.2
Robertson, E.J.3
Efstratiadis, A.4
-
2
-
-
1242295315
-
Wnt1-cre mediated deletion of AP-2a causes multiple neural crest-related defects
-
Brewer S., Feng W., Huang J., Sullivan S., and Williams T. Wnt1-cre mediated deletion of AP-2a causes multiple neural crest-related defects. Dev. Biol. 267 (2004) 135-152
-
(2004)
Dev. Biol.
, vol.267
, pp. 135-152
-
-
Brewer, S.1
Feng, W.2
Huang, J.3
Sullivan, S.4
Williams, T.5
-
3
-
-
0035692012
-
Molecular effects of novel mutations in Hesx1/HESX1 associated with human pituitary disorders
-
Brickman J.M., Clements M., Tyrell R., McNay D., Woods K., Warner J., Stewart A., Beddington R.S., and Dattani M. Molecular effects of novel mutations in Hesx1/HESX1 associated with human pituitary disorders. Development 128 (2001) 5189-5199
-
(2001)
Development
, vol.128
, pp. 5189-5199
-
-
Brickman, J.M.1
Clements, M.2
Tyrell, R.3
McNay, D.4
Woods, K.5
Warner, J.6
Stewart, A.7
Beddington, R.S.8
Dattani, M.9
-
4
-
-
0034057170
-
Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis
-
Chai Y., Jiang X., Ito Y., Bringas Jr. P., Han J., Rowitch D.H., Soriano P., McMahon A.P., and Sucov H.M. Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. Development 127 (2000) 1671-1679
-
(2000)
Development
, vol.127
, pp. 1671-1679
-
-
Chai, Y.1
Jiang, X.2
Ito, Y.3
Bringas Jr., P.4
Han, J.5
Rowitch, D.H.6
Soriano, P.7
McMahon, A.P.8
Sucov, H.M.9
-
5
-
-
0023687125
-
The fate map of the cephalic neural primordium at the presomitic to the 3-somite stage in the avian embryo
-
Couly G., and Le Douarin N.M. The fate map of the cephalic neural primordium at the presomitic to the 3-somite stage in the avian embryo. Development 103 Suppl. (1988) 101-113
-
(1988)
Development
, vol.103
, Issue.SUPPL
, pp. 101-113
-
-
Couly, G.1
Le Douarin, N.M.2
-
6
-
-
21444457762
-
Growth hormone receptor is a target for presenilin-dependent gamma-secretase cleavage
-
Cowan J.W., Wang X., Guan R., He K., Jiang J., Baumann G., Black R.A., Wolfe M.S., and Frank S.J. Growth hormone receptor is a target for presenilin-dependent gamma-secretase cleavage. J. Biol. Chem. 280 (2005) 19331-19342
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 19331-19342
-
-
Cowan, J.W.1
Wang, X.2
Guan, R.3
He, K.4
Jiang, J.5
Baumann, G.6
Black, R.A.7
Wolfe, M.S.8
Frank, S.J.9
-
7
-
-
0032408458
-
Molecular genetics of Alzheimer's disease
-
Cruts M., and Van Broeckhoven C. Molecular genetics of Alzheimer's disease. Ann. Med. 30 (1998) 560-565
-
(1998)
Ann. Med.
, vol.30
, pp. 560-565
-
-
Cruts, M.1
Van Broeckhoven, C.2
-
8
-
-
0031938304
-
Presenilin mutations in Alzheimer's disease
-
Cruts M., and Van Broeckhoven C. Presenilin mutations in Alzheimer's disease. Hum. Mutat. 11 (1998) 183-190
-
(1998)
Hum. Mutat.
, vol.11
, pp. 183-190
-
-
Cruts, M.1
Van Broeckhoven, C.2
-
9
-
-
0032481124
-
Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase
-
Danielian P.S., Muccino D., Rowitch D.H., Michael S.K., and McMahon A.P. Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Curr. Biol. 8 (1998) 1323-1326
-
(1998)
Curr. Biol.
, vol.8
, pp. 1323-1326
-
-
Danielian, P.S.1
Muccino, D.2
Rowitch, D.H.3
Michael, S.K.4
McMahon, A.P.5
-
10
-
-
23244433749
-
Growth hormone deficiency and combined pituitary hormone deficiency: does the genotype matter?
-
Dattani M.T. Growth hormone deficiency and combined pituitary hormone deficiency: does the genotype matter?. Clin. Endocrinol. (Oxf.) 63 (2005) 121-130
-
(2005)
Clin. Endocrinol. (Oxf.)
, vol.63
, pp. 121-130
-
-
Dattani, M.T.1
-
11
-
-
0024355048
-
Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations
-
Daughaday W.H., and Rotwein P. Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocr. Rev. 10 (1989) 68-91
-
(1989)
Endocr. Rev.
, vol.10
, pp. 68-91
-
-
Daughaday, W.H.1
Rotwein, P.2
-
12
-
-
0033535504
-
A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain
-
De Strooper B., Annaert W., Cupers P., Saftig P., Craessaerts K., Mumm J.S., Schroeter E.H., Schrijvers V., Wolfe M.S., Ray W.J., Goate A., and Kopan R. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature 398 (1999) 518-522
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
Annaert, W.2
Cupers, P.3
Saftig, P.4
Craessaerts, K.5
Mumm, J.S.6
Schroeter, E.H.7
Schrijvers, V.8
Wolfe, M.S.9
Ray, W.J.10
Goate, A.11
Kopan, R.12
-
13
-
-
0027455584
-
Growth hormone deficiency in 'little' mice results in aberrant body composition, reduced insulin-like growth factor-I and insulin-like growth factor-binding protein-3 (IGFBP-3), but does not affect IGFBP-2, -1 or -4
-
Donahue L.R., and Beamer W.G. Growth hormone deficiency in 'little' mice results in aberrant body composition, reduced insulin-like growth factor-I and insulin-like growth factor-binding protein-3 (IGFBP-3), but does not affect IGFBP-2, -1 or -4. J. Endocrinol. 136 (1993) 91-104
-
(1993)
J. Endocrinol.
, vol.136
, pp. 91-104
-
-
Donahue, L.R.1
Beamer, W.G.2
-
14
-
-
0032728957
-
Mice lacking both presenilin genes exhibit early embryonic patterning defects
-
Donoviel D.B., Hadjantonakis A.K., Ikeda M., Zheng H., Hyslop P.S., and Bernstein A. Mice lacking both presenilin genes exhibit early embryonic patterning defects. Genes Dev. 13 (1999) 2801-2810
-
(1999)
Genes Dev.
, vol.13
, pp. 2801-2810
-
-
Donoviel, D.B.1
Hadjantonakis, A.K.2
Ikeda, M.3
Zheng, H.4
Hyslop, P.S.5
Bernstein, A.6
-
15
-
-
0025234605
-
Mapping of the presumptive brain regions in the neural plate of Xenopus laevis
-
Eagleson G.W., and Harris W.A. Mapping of the presumptive brain regions in the neural plate of Xenopus laevis. J. Neurobiol. 21 (1990) 427-440
-
(1990)
J. Neurobiol.
, vol.21
, pp. 427-440
-
-
Eagleson, G.W.1
Harris, W.A.2
-
16
-
-
7244229604
-
Distinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes
-
Gottardi C.J., and Gumbiner B.M. Distinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes. J. Cell Biol. 167 (2004) 339-349
-
(2004)
J. Cell Biol.
, vol.167
, pp. 339-349
-
-
Gottardi, C.J.1
Gumbiner, B.M.2
-
17
-
-
0033945494
-
Presenilin-1 regulates neuronal differentiation during neurogenesis
-
Handler M., Yang X., and Shen J. Presenilin-1 regulates neuronal differentiation during neurogenesis. Development 127 (2000) 2593-2606
-
(2000)
Development
, vol.127
, pp. 2593-2606
-
-
Handler, M.1
Yang, X.2
Shen, J.3
-
18
-
-
0034010326
-
Fate of the mammalian cardiac neural crest
-
Jiang X., Rowitch D.H., Soriano P., McMahon A.P., and Sucov H.M. Fate of the mammalian cardiac neural crest. Development 127 (2000) 1607-1616
-
(2000)
Development
, vol.127
, pp. 1607-1616
-
-
Jiang, X.1
Rowitch, D.H.2
Soriano, P.3
McMahon, A.P.4
Sucov, H.M.5
-
19
-
-
0037145062
-
Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis
-
Kang D.E., Soriano S., Xia X., Eberhart C.G., De Strooper B., Zheng H., and Koo E.H. Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis. Cell 110 (2002) 751-762
-
(2002)
Cell
, vol.110
, pp. 751-762
-
-
Kang, D.E.1
Soriano, S.2
Xia, X.3
Eberhart, C.G.4
De Strooper, B.5
Zheng, H.6
Koo, E.H.7
-
20
-
-
0025941823
-
Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid
-
Kessel M., and Gruss P. Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid. Cell 67 (1991) 89-104
-
(1991)
Cell
, vol.67
, pp. 89-104
-
-
Kessel, M.1
Gruss, P.2
-
21
-
-
0035042946
-
The role of presenilin 1 during somite segmentation
-
Koizumi K., Nakajima M., Yuasa S., Saga Y., Sakai T., Kuriyama T., Shirasawa T., and Koseki H. The role of presenilin 1 during somite segmentation. Development 128 (2001) 1391-1402
-
(2001)
Development
, vol.128
, pp. 1391-1402
-
-
Koizumi, K.1
Nakajima, M.2
Yuasa, S.3
Saga, Y.4
Sakai, T.5
Kuriyama, T.6
Shirasawa, T.7
Koseki, H.8
-
22
-
-
3142512452
-
Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration
-
Koo E.H., and Kopan R. Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration. Nat. Med. 10 (2004) S26-33
-
(2004)
Nat. Med.
, vol.10
-
-
Koo, E.H.1
Kopan, R.2
-
23
-
-
0033608980
-
Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice
-
Mao X., Fujiwara Y., and Orkin S.H. Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 5037-5042
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 5037-5042
-
-
Mao, X.1
Fujiwara, Y.2
Orkin, S.H.3
-
24
-
-
18344380083
-
A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions
-
Marambaud P., Shioi J., Serban G., Georgakopoulos A., Sarner S., Nagy V., Baki L., Wen P., Efthimiopoulos S., Shao Z., Wisniewski T., and Robakis N.K. A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions. EMBO J. 21 (2002) 1948-1956
-
(2002)
EMBO J.
, vol.21
, pp. 1948-1956
-
-
Marambaud, P.1
Shioi, J.2
Serban, G.3
Georgakopoulos, A.4
Sarner, S.5
Nagy, V.6
Baki, L.7
Wen, P.8
Efthimiopoulos, S.9
Shao, Z.10
Wisniewski, T.11
Robakis, N.K.12
-
25
-
-
0141429160
-
A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations
-
Marambaud P., Wen P.H., Dutt A., Shioi J., Takashima A., Siman R., and Robakis N.K. A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations. Cell 114 (2003) 635-645
-
(2003)
Cell
, vol.114
, pp. 635-645
-
-
Marambaud, P.1
Wen, P.H.2
Dutt, A.3
Shioi, J.4
Takashima, A.5
Siman, R.6
Robakis, N.K.7
-
26
-
-
0037371936
-
Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms
-
Mohan S., Richman C., Guo R., Amaar Y., Donahue L.R., Wergedal J., and Baylink D.J. Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms. Endocrinology 144 (2003) 929-936
-
(2003)
Endocrinology
, vol.144
, pp. 929-936
-
-
Mohan, S.1
Richman, C.2
Guo, R.3
Amaar, Y.4
Donahue, L.R.5
Wergedal, J.6
Baylink, D.J.7
-
28
-
-
0038354566
-
Abnormal blood vessel development in mice lacking presenilin-1
-
Nakajima M., Yuasa S., Ueno M., Takakura N., Koseki H., and Shirasawa T. Abnormal blood vessel development in mice lacking presenilin-1. Mech. Dev. 120 (2003) 657-667
-
(2003)
Mech. Dev.
, vol.120
, pp. 657-667
-
-
Nakajima, M.1
Yuasa, S.2
Ueno, M.3
Takakura, N.4
Koseki, H.5
Shirasawa, T.6
-
29
-
-
11144354609
-
Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration
-
Saura C.A., Choi S.Y., Beglopoulos V., Malkani S., Zhang D., Shankaranarayana Rao B.S., Chattarji S., Kelleher III R.J., Kandel E.R., Duff K., Kirkwood A., and Shen J. Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration. Neuron 42 (2004) 23-36
-
(2004)
Neuron
, vol.42
, pp. 23-36
-
-
Saura, C.A.1
Choi, S.Y.2
Beglopoulos, V.3
Malkani, S.4
Zhang, D.5
Shankaranarayana Rao, B.S.6
Chattarji, S.7
Kelleher III, R.J.8
Kandel, E.R.9
Duff, K.10
Kirkwood, A.11
Shen, J.12
-
30
-
-
0030779784
-
Skeletal and CNS defects in presenilin-1-deficient mice
-
Shen J., Bronson R.T., Chen D.F., Xia W., Selkoe D.J., and Tonegawa S. Skeletal and CNS defects in presenilin-1-deficient mice. Cell 89 (1997) 629-639
-
(1997)
Cell
, vol.89
, pp. 629-639
-
-
Shen, J.1
Bronson, R.T.2
Chen, D.F.3
Xia, W.4
Selkoe, D.J.5
Tonegawa, S.6
-
31
-
-
0034676035
-
Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous system
-
Tomita K., Moriyoshi K., Nakanishi S., Guillemot F., and Kageyama R. Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous system. EMBO J. 19 (2000) 5460-5472
-
(2000)
EMBO J.
, vol.19
, pp. 5460-5472
-
-
Tomita, K.1
Moriyoshi, K.2
Nakanishi, S.3
Guillemot, F.4
Kageyama, R.5
-
32
-
-
2642653223
-
Multistep signaling requirements for pituitary organogenesis in vivo
-
Treier M., Gleiberman A.S., O'Connell S.M., Szeto D.P., McMahon J.A., McMahon A.P., and Rosenfeld M.G. Multistep signaling requirements for pituitary organogenesis in vivo. Genes Dev. 12 (1998) 1691-1704
-
(1998)
Genes Dev.
, vol.12
, pp. 1691-1704
-
-
Treier, M.1
Gleiberman, A.S.2
O'Connell, S.M.3
Szeto, D.P.4
McMahon, J.A.5
McMahon, A.P.6
Rosenfeld, M.G.7
-
33
-
-
17744401440
-
Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm
-
Wong P.C., Zheng H., Chen H., Becher M.W., Sirinathsinghji D.J., Trumbauer M.E., Chen H.Y., Price D.L., Van der Ploeg L.H., and Sisodia S.S. Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm. Nature 387 (1997) 288-292
-
(1997)
Nature
, vol.387
, pp. 288-292
-
-
Wong, P.C.1
Zheng, H.2
Chen, H.3
Becher, M.W.4
Sirinathsinghji, D.J.5
Trumbauer, M.E.6
Chen, H.Y.7
Price, D.L.8
Van der Ploeg, L.H.9
Sisodia, S.S.10
-
34
-
-
17944376442
-
APP processing and synaptic plasticity in presenilin-1 conditional knockout mice
-
Yu H., Saura C.A., Choi S.Y., Sun L.D., Yang X., Handler M., Kawarabayashi T., Younkin L., Fedeles B., Wilson M.A., Younkin S., Kandel E.R., Kirkwood A., and Shen J. APP processing and synaptic plasticity in presenilin-1 conditional knockout mice. Neuron 31 (2001) 713-726
-
(2001)
Neuron
, vol.31
, pp. 713-726
-
-
Yu, H.1
Saura, C.A.2
Choi, S.Y.3
Sun, L.D.4
Yang, X.5
Handler, M.6
Kawarabayashi, T.7
Younkin, L.8
Fedeles, B.9
Wilson, M.A.10
Younkin, S.11
Kandel, E.R.12
Kirkwood, A.13
Shen, J.14
-
35
-
-
0037010306
-
Impaired cell cycle control of neuronal precursor cells in the neocortical primordium of presenilin-1-deficient mice
-
Yuasa S., Nakajima M., Aizawa H., Sahara N., Koizumi K., Sakai T., Usami M., Kobayashi S., Kuroyanagi H., Mori H., Koseki H., and Shirasawa T. Impaired cell cycle control of neuronal precursor cells in the neocortical primordium of presenilin-1-deficient mice. J. Neurosci. Res. 70 (2002) 501-513
-
(2002)
J. Neurosci. Res.
, vol.70
, pp. 501-513
-
-
Yuasa, S.1
Nakajima, M.2
Aizawa, H.3
Sahara, N.4
Koizumi, K.5
Sakai, T.6
Usami, M.7
Kobayashi, S.8
Kuroyanagi, H.9
Mori, H.10
Koseki, H.11
Shirasawa, T.12
-
36
-
-
33749316349
-
Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis
-
Zhu X., Zhang J., Tollkuhn J., Ohsawa R., Bresnick E.H., Guillemot F., Kageyama R., and Rosenfeld M.G. Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. Genes Dev. 20 (2006) 2739-2753
-
(2006)
Genes Dev.
, vol.20
, pp. 2739-2753
-
-
Zhu, X.1
Zhang, J.2
Tollkuhn, J.3
Ohsawa, R.4
Bresnick, E.H.5
Guillemot, F.6
Kageyama, R.7
Rosenfeld, M.G.8
|