Gene therapy approaches to induce tolerance in autoimmunity by reshaping the immune system

Current Opinion in Investigational Drugs

Volumn 10, Issue 11, 2009, Pages 1143-1150

  Wasserfall, C H ^a   Herzog, R W ^b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Autoimmume disease gene therapy; Immunoregulation; Multiple sclerosis; Rheumatoid arthritis; Systemic lupus erythematosus

Indexed keywords

DNA VACCINE; GALECTIN 1; GLUTAMATE DECARBOXYLASE; IMMUNOGLOBULIN G; INTERLEUKIN 10; INTERLEUKIN 18; INTERLEUKIN 4; PARVOVIRUS VECTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BCL 2; PROTEIN KINASE B; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TRANSCRIPTION FACTOR PDX 1;

ALLERGIC ENCEPHALOMYELITIS; ARTHRITIS; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CLINICAL TRIAL; DOWN REGULATION; EX VIVO GENE TRANSFER; GENE SILENCING; GENE THERAPY; HUMAN; IMMUNE SYSTEM; IMMUNOLOGICAL TOLERANCE; IN VIVO GENE TRANSFER; INSULIN DEPENDENT DIABETES MELLITUS; MULTIPLE SCLEROSIS; NONHUMAN; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; REVIEW; SIGNAL TRANSDUCTION; TREATMENT RESPONSE;

ANIMALS; AUTOANTIGENS; AUTOIMMUNE DISEASES; CLINICAL TRIALS AS TOPIC; GENE THERAPY; GENE TRANSFER TECHNIQUES; HUMANS; IMMUNE TOLERANCE; SEVERITY OF ILLNESS INDEX;

EID: 70449334563     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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