Anti-inflammatory cytokine gene therapy decreases sensory and motor dysfunction in experimental Multiple Sclerosis: MOG-EAE behavioral and anatomical symptom treatment with cytokine gene therapy

Brain, Behavior, and Immunity

Volumn 23, Issue 1, 2009, Pages 92-100

  Sloane, Evan ^a   Ledeboer, A ^b   Seibert, W ^a   Coats, B ^a   van Strien, M ^c   Maier, S F ^a   Johnson, K W ^b   Chavez, R ^b   Watkins, L R ^a   Leinwand, L ^a   Milligan, E D ^d   Van Dam, A M ^c  

^a UNIVERSITY OF COLORADO   (United States)

^b Avigen Inc   (United States)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

Author keywords

EAE; IL 10; MOG; Neuropathic pain; Non viral gene therapy; Numbness

Indexed keywords

CYTOKINE; INTERLEUKIN 10; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; PLASMID DNA;

ALLERGIC ENCEPHALOMYELITIS; ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; GENE THERAPY; MALE; MOTOR DYSFUNCTION; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY DYSFUNCTION;

ANALYSIS OF VARIANCE; ANIMALS; BODY WEIGHT; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENE THERAPY; GLIAL FIBRILLARY ACIDIC PROTEIN; HINDLIMB; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERLEUKIN-10; MALE; MOTOR ACTIVITY; MULTIPLE SCLEROSIS; MYELIN-ASSOCIATED GLYCOPROTEIN; NEURALGIA; PARALYSIS; RATS; RATS, INBRED STRAINS; SPINAL CORD; TIME FACTORS;

EID: 56949102067     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2008.09.004     Document Type: Article

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