Synthesis, estrogen receptor binding, and tissue distribution of a new iodovinylestradiol derivative (17α,20E)-21-[123I]iodo-11β-nitrato-19- norpregna-1,3,5(10),20-tetraene-3,17-diol (E-[123I]NIVE)

Nuclear Medicine and Biology

Volumn 25, Issue 4, 1998, Pages 411-421

  Rijks, Leonie J M ^a   Van Den Bos, Jan C ^b   Van Doremalen, Peter A P M ^b   Boer, Gerard J ^a   De Bruin, Kora ^a   Doornbos, Tamme ^b   Vekemans, Jozef A J M ^b   Posthumus, Maarten A ^c   Janssen, Anton G M ^b   Van Royen, Eric A ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^c WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

11 Nitrato 17 123I iodovinylestradiol; Breast tumor imaging; Estrogen receptor radioligand; Mature tumor bearing rat; Single photon emission computed tomography

Indexed keywords

11BETA METHOXY 17ALPHA IODOVINYLESTRADIOL; 11BETA NITRATO 17ALPHA IODOVINYLESTRADIOL; 21 IODO 11BETA NITRATO 19 NORPREGNA 1,3,5(10),20 TETRAENE 3,17 DIOL I 123; ESTRADIOL DERIVATIVE; ESTROGEN RECEPTOR; IODINE 123; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOMA; CONTROLLED STUDY; DRUG SYNTHESIS; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOISOTOPE DISTRIBUTION; RAT; RECEPTOR AFFINITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STEREOCHEMISTRY;

ANIMALS; BINDING, COMPETITIVE; BREAST NEOPLASMS; ESTRADIOL; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; IODINE RADIOISOTOPES; MAMMARY NEOPLASMS, EXPERIMENTAL; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTROGEN; SEX HORMONE-BINDING GLOBULIN; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TUMOR CELLS, CULTURED;

EID: 0031961153     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(97)00223-0     Document Type: Article

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