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Volumn 94, Issue 6, 2009, Pages 397-406

Isolation of cancer-specific chimeric transcripts induced by hypomethylation of the LINE-1 antisense promoter

Author keywords

Breast cancer; Chimeric transcripts; Colon cancer; Hypomethylation; LINE 1; Retrotransposon

Indexed keywords

AZACITIDINE; CHIMERIC PROTEIN; PROTEIN LCT1; PROTEIN LCT10; PROTEIN LCT11; PROTEIN LCT12; PROTEIN LCT13; PROTEIN LCT14; PROTEIN LCT15; PROTEIN LCT16; PROTEIN LCT17; PROTEIN LCT18; PROTEIN LCT2; PROTEIN LCT3; PROTEIN LCT4; PROTEIN LCT5; PROTEIN LCT6; PROTEIN LCT7; PROTEIN LCT8; PROTEIN LCT9; UNCLASSIFIED DRUG;

EID: 70449107061     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1016/j.ygeno.2009.08.013     Document Type: Article
Times cited : (85)

References (43)
  • 1
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander E.S., et al. Initial sequencing and analysis of the human genome. Nature 409 (2001) 860-921
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1
  • 2
    • 0034999474 scopus 로고    scopus 로고
    • Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes
    • Speek M. Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes. Mol. Cell. Biol. 21 (2001) 1973-1985
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1973-1985
    • Speek, M.1
  • 4
    • 33645466204 scopus 로고    scopus 로고
    • LINE-1 RNA splicing and influences on mammalian gene expression
    • Belancio V.P., Hedges D.J., and Deininger P. LINE-1 RNA splicing and influences on mammalian gene expression. Nucleic Acids Res. 34 (2006) 1512-1521
    • (2006) Nucleic Acids Res. , vol.34 , pp. 1512-1521
    • Belancio, V.P.1    Hedges, D.J.2    Deininger, P.3
  • 5
    • 23744454779 scopus 로고    scopus 로고
    • Gene-breaking: a new paradigm for human retrotransposon-mediated gene evolution
    • Wheelan S.J., Aizawa Y., Han J.S., and Boeke J.D. Gene-breaking: a new paradigm for human retrotransposon-mediated gene evolution. Genome Res. 15 (2005) 1073-1078
    • (2005) Genome Res. , vol.15 , pp. 1073-1078
    • Wheelan, S.J.1    Aizawa, Y.2    Han, J.S.3    Boeke, J.D.4
  • 6
    • 2442667886 scopus 로고    scopus 로고
    • Transcriptional disruption by the L1 retrotransposon and implications for mammalian transcriptomes
    • Han J.S., Szak S.T., and Boeke J.D. Transcriptional disruption by the L1 retrotransposon and implications for mammalian transcriptomes. Nature 429 (2004) 268-274
    • (2004) Nature , vol.429 , pp. 268-274
    • Han, J.S.1    Szak, S.T.2    Boeke, J.D.3
  • 7
    • 33749627376 scopus 로고    scopus 로고
    • Long L1 insertions in human gene introns specifically reduce the content of corresponding primary transcripts
    • Ustyugova S.V., Lebedev Y.B., and Sverdlov E.D. Long L1 insertions in human gene introns specifically reduce the content of corresponding primary transcripts. Genetica 128 (2006) 261-272
    • (2006) Genetica , vol.128 , pp. 261-272
    • Ustyugova, S.V.1    Lebedev, Y.B.2    Sverdlov, E.D.3
  • 8
    • 0036251775 scopus 로고    scopus 로고
    • Many human genes are transcribed from the antisense promoter of L1 retrotransposon
    • Nigumann P., Redik K., Matlik K., and Speek M. Many human genes are transcribed from the antisense promoter of L1 retrotransposon. Genomics 79 (2002) 628-634
    • (2002) Genomics , vol.79 , pp. 628-634
    • Nigumann, P.1    Redik, K.2    Matlik, K.3    Speek, M.4
  • 9
    • 33746658129 scopus 로고    scopus 로고
    • L1 antisense promoter drives tissue-specific transcription of human genes
    • Matlik K., Redik K., and Speek M. L1 antisense promoter drives tissue-specific transcription of human genes. J. Biomed. Biotechnol. 2006 (2006) 71753
    • (2006) J. Biomed. Biotechnol. , vol.2006 , pp. 71753
    • Matlik, K.1    Redik, K.2    Speek, M.3
  • 10
    • 38549133553 scopus 로고    scopus 로고
    • Human cis natural antisense transcripts initiated by transposable elements
    • Conley A.B., Miller W.J., and Jordan I.K. Human cis natural antisense transcripts initiated by transposable elements. Trends Genet. 24 (2008) 53-56
    • (2008) Trends Genet. , vol.24 , pp. 53-56
    • Conley, A.B.1    Miller, W.J.2    Jordan, I.K.3
  • 11
    • 0030826364 scopus 로고    scopus 로고
    • Intergenic transcription and transinduction of the human beta-globin locus
    • Ashe H.L., Monks J., Wijgerde M., Fraser P., and Proudfoot N.J. Intergenic transcription and transinduction of the human beta-globin locus. Genes Dev. 11 (1997) 2494-2509
    • (1997) Genes Dev. , vol.11 , pp. 2494-2509
    • Ashe, H.L.1    Monks, J.2    Wijgerde, M.3    Fraser, P.4    Proudfoot, N.J.5
  • 12
    • 2942691957 scopus 로고    scopus 로고
    • Antisense intergenic transcription in V(D)J recombination
    • Bolland D.J., et al. Antisense intergenic transcription in V(D)J recombination. Nat. Immunol. 5 (2004) 630-637
    • (2004) Nat. Immunol. , vol.5 , pp. 630-637
    • Bolland, D.J.1
  • 13
    • 0033853988 scopus 로고    scopus 로고
    • Intergenic transcription and developmental remodeling of chromatin subdomains in the human beta-globin locus
    • Gribnau J., Diderich K., Pruzina S., Calzolari R., and Fraser P. Intergenic transcription and developmental remodeling of chromatin subdomains in the human beta-globin locus. Mol. Cell 5 (2000) 377-386
    • (2000) Mol. Cell , vol.5 , pp. 377-386
    • Gribnau, J.1    Diderich, K.2    Pruzina, S.3    Calzolari, R.4    Fraser, P.5
  • 14
    • 0022533498 scopus 로고
    • Transcriptional interference and termination between duplicated alpha-globin gene constructs suggests a novel mechanism for gene regulation
    • Proudfoot N.J. Transcriptional interference and termination between duplicated alpha-globin gene constructs suggests a novel mechanism for gene regulation. Nature 322 (1986) 562-565
    • (1986) Nature , vol.322 , pp. 562-565
    • Proudfoot, N.J.1
  • 15
    • 0038581890 scopus 로고    scopus 로고
    • Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease
    • Tufarelli C., et al. Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease. Nat. Genet. 34 (2003) 157-165
    • (2003) Nat. Genet. , vol.34 , pp. 157-165
    • Tufarelli, C.1
  • 16
    • 38049155825 scopus 로고    scopus 로고
    • Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA
    • Yu W., et al. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature 451 (2008) 202-206
    • (2008) Nature , vol.451 , pp. 202-206
    • Yu, W.1
  • 17
    • 33644755464 scopus 로고    scopus 로고
    • Multiple forms of genetic instability within a 2-Mb chromosomal segment of 3q26.3-q27 are associated with development of esophageal adenocarcinoma
    • Lin L., et al. Multiple forms of genetic instability within a 2-Mb chromosomal segment of 3q26.3-q27 are associated with development of esophageal adenocarcinoma. Genes, Chromosomes Cancer 45 (2006) 319-331
    • (2006) Genes, Chromosomes Cancer , vol.45 , pp. 319-331
    • Lin, L.1
  • 18
    • 27944504788 scopus 로고    scopus 로고
    • Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia
    • Roman-Gomez J., et al. Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia. Oncogene 24 (2005) 7213-7223
    • (2005) Oncogene , vol.24 , pp. 7213-7223
    • Roman-Gomez, J.1
  • 19
    • 0020699979 scopus 로고
    • Hypomethylation distinguishes genes of some human cancers from their normal counterparts
    • Feinberg A.P., and Vogelstein B. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 301 (1983) 89-92
    • (1983) Nature , vol.301 , pp. 89-92
    • Feinberg, A.P.1    Vogelstein, B.2
  • 21
    • 0242584449 scopus 로고    scopus 로고
    • Induction of tumors in mice by genomic hypomethylation
    • F. Gaudet, et al., Induction of tumors in mice by genomic hypomethylation. Science 300 (2003) 489-492.
    • (2003) Science , vol.300 , pp. 489-492
    • Gaudet, F.1
  • 22
    • 0242584454 scopus 로고    scopus 로고
    • Chromosomal instability and tumors promoted by DNA hypomethylation
    • Eden A., Gaudet F., Waghmare A., and Jaenisch R. Chromosomal instability and tumors promoted by DNA hypomethylation. Science 300 (2003) 455
    • (2003) Science , vol.300 , pp. 455
    • Eden, A.1    Gaudet, F.2    Waghmare, A.3    Jaenisch, R.4
  • 23
    • 0033135573 scopus 로고    scopus 로고
    • High frequency of alterations in DNA methylation in adenocarcinoma of the prostate
    • Santourlidis S., Florl A., Ackermann R., Wirtz H.C., and Schulz W.A. High frequency of alterations in DNA methylation in adenocarcinoma of the prostate. Prostate 39 (1999) 166-174
    • (1999) Prostate , vol.39 , pp. 166-174
    • Santourlidis, S.1    Florl, A.2    Ackermann, R.3    Wirtz, H.C.4    Schulz, W.A.5
  • 24
    • 39749193874 scopus 로고    scopus 로고
    • Repetitive DNA hypomethylation in the advanced phase of chronic myeloid leukemia
    • Roman-Gomez J., et al. Repetitive DNA hypomethylation in the advanced phase of chronic myeloid leukemia. Leuk. Res. 32 (2008) 487-490
    • (2008) Leuk. Res. , vol.32 , pp. 487-490
    • Roman-Gomez, J.1
  • 25
    • 0037047355 scopus 로고    scopus 로고
    • Genomic deletions created upon LINE-1 retrotransposition
    • Gilbert N., Lutz-Prigge S., and Moran J.V. Genomic deletions created upon LINE-1 retrotransposition. Cell 110 (2002) 315-325
    • (2002) Cell , vol.110 , pp. 315-325
    • Gilbert, N.1    Lutz-Prigge, S.2    Moran, J.V.3
  • 26
    • 38049164130 scopus 로고    scopus 로고
    • Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice
    • Howard G., Eiges R., Gaudet F., Jaenisch R., and Eden A. Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice. Oncogene 27 (2008) 404-408
    • (2008) Oncogene , vol.27 , pp. 404-408
    • Howard, G.1    Eiges, R.2    Gaudet, F.3    Jaenisch, R.4    Eden, A.5
  • 27
    • 0037047396 scopus 로고    scopus 로고
    • Human l1 retrotransposition is associated with genetic instability in vivo
    • Symer D.E., et al. Human l1 retrotransposition is associated with genetic instability in vivo. Cell 110 (2002) 327-338
    • (2002) Cell , vol.110 , pp. 327-338
    • Symer, D.E.1
  • 28
    • 0042346386 scopus 로고    scopus 로고
    • Enrichment for histone H3 lysine 9 methylation at Alu repeats in human cells
    • Kondo Y., and Issa J.P. Enrichment for histone H3 lysine 9 methylation at Alu repeats in human cells. J. Biol. Chem. 278 (2003) 27658-27662
    • (2003) J. Biol. Chem. , vol.278 , pp. 27658-27662
    • Kondo, Y.1    Issa, J.P.2
  • 29
    • 0030840954 scopus 로고    scopus 로고
    • Cytosine methylation and the ecology of intragenomic parasites
    • Yoder J.A., Walsh C.P., and Bestor T.H. Cytosine methylation and the ecology of intragenomic parasites. Trends Genet. 13 (1997) 335-340
    • (1997) Trends Genet. , vol.13 , pp. 335-340
    • Yoder, J.A.1    Walsh, C.P.2    Bestor, T.H.3
  • 30
    • 0035678749 scopus 로고    scopus 로고
    • Selective differential display of RNAs containing interspersed repeats: analysis of changes in the transcription of HERV-K LTRs in germ cell tumors
    • Vinogradova T., et al. Selective differential display of RNAs containing interspersed repeats: analysis of changes in the transcription of HERV-K LTRs in germ cell tumors. Mol. Genet. Genomics 266 (2002) 796-805
    • (2002) Mol. Genet. Genomics , vol.266 , pp. 796-805
    • Vinogradova, T.1
  • 32
    • 33748363713 scopus 로고    scopus 로고
    • L1 retrotransposition is suppressed by endogenously encoded small interfering RNAs in human cultured cells
    • Yang N., and Kazazian Jr. H.H. L1 retrotransposition is suppressed by endogenously encoded small interfering RNAs in human cultured cells. Nat. Struct. Mol. Biol. 13 (2006) 763-771
    • (2006) Nat. Struct. Mol. Biol. , vol.13 , pp. 763-771
    • Yang, N.1    Kazazian Jr., H.H.2
  • 33
    • 36849059066 scopus 로고    scopus 로고
    • LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability
    • Estecio M.R., et al. LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability. PLoS ONE 2 (2007) e399
    • (2007) PLoS ONE , vol.2
    • Estecio, M.R.1
  • 35
    • 0032901199 scopus 로고    scopus 로고
    • Cytosine methylation and mammalian development
    • Walsh C.P., and Bestor T.H. Cytosine methylation and mammalian development. Genes Dev. 13 (1999) 26-34
    • (1999) Genes Dev. , vol.13 , pp. 26-34
    • Walsh, C.P.1    Bestor, T.H.2
  • 36
    • 0025129726 scopus 로고
    • Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10
    • Soule H.D., et al. Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res. 50 (1990) 6075-6086
    • (1990) Cancer Res. , vol.50 , pp. 6075-6086
    • Soule, H.D.1
  • 37
    • 33646256347 scopus 로고    scopus 로고
    • Extensive individual variation in L1 retrotransposition capability contributes to human genetic diversity
    • Seleme M.C., et al. Extensive individual variation in L1 retrotransposition capability contributes to human genetic diversity. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 6611-6616
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 6611-6616
    • Seleme, M.C.1
  • 38
    • 0033664012 scopus 로고    scopus 로고
    • Validation of a model of colon cancer progression
    • Hewitt R.E., et al. Validation of a model of colon cancer progression. J. Pathol. 192 (2000) 446-454
    • (2000) J. Pathol. , vol.192 , pp. 446-454
    • Hewitt, R.E.1
  • 39
    • 34548816772 scopus 로고    scopus 로고
    • Protein and mRNA characterization in human colorectal carcinoma cell lines with different metastatic potentials
    • Liang L., Qu L., and Ding Y. Protein and mRNA characterization in human colorectal carcinoma cell lines with different metastatic potentials. Cancer Invest. 25 (2007) 427-434
    • (2007) Cancer Invest. , vol.25 , pp. 427-434
    • Liang, L.1    Qu, L.2    Ding, Y.3
  • 40
    • 0033811848 scopus 로고    scopus 로고
    • Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cell lines
    • Parle-McDermott A., McWilliam P., Tighe O., Dunican D., and Croke D.T. Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cell lines. Br. J. Cancer 83 (2000) 725-728
    • (2000) Br. J. Cancer , vol.83 , pp. 725-728
    • Parle-McDermott, A.1    McWilliam, P.2    Tighe, O.3    Dunican, D.4    Croke, D.T.5
  • 41
    • 32944476464 scopus 로고    scopus 로고
    • Expression of LINE-1 retroposons is essential for murine preimplantation development
    • Beraldi R., Pittoggi C., Sciamanna I., Mattei E., and Spadafora C. Expression of LINE-1 retroposons is essential for murine preimplantation development. Mol. Reprod. Dev. 73 (2006) 279-287
    • (2006) Mol. Reprod. Dev. , vol.73 , pp. 279-287
    • Beraldi, R.1    Pittoggi, C.2    Sciamanna, I.3    Mattei, E.4    Spadafora, C.5
  • 42
    • 0030471926 scopus 로고    scopus 로고
    • A modified and improved method for bisulphite based cytosine methylation analysis
    • Olek A., Oswald J., and Walter J. A modified and improved method for bisulphite based cytosine methylation analysis. Nucleic Acids Res. 24 (1996) 5064-5066
    • (1996) Nucleic Acids Res. , vol.24 , pp. 5064-5066
    • Olek, A.1    Oswald, J.2    Walter, J.3
  • 43
    • 0037383453 scopus 로고    scopus 로고
    • ATLAS: a system to selectively identify human-specific L1 insertions
    • Badge R.M., Alisch R.S., and Moran J.V. ATLAS: a system to selectively identify human-specific L1 insertions. Am. J. Hum. Genet. 72 (2003) 823-838
    • (2003) Am. J. Hum. Genet. , vol.72 , pp. 823-838
    • Badge, R.M.1    Alisch, R.S.2    Moran, J.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.