Expression of LINE-1 retroposons is essential for murine preimplantation development

Molecular Reproduction and Development

Volumn 73, Issue 3, 2006, Pages 279-287

  Beraldi, Rosanna ^a,b   Pittoggi, Carmine ^b   Sciamanna, Ilaria ^b   Mattei, Elisabetta ^c   Spadafora, Corrado ^b  

^a UNIVERSITY OF SIENA   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c CNR   (Italy)

Author keywords

Developmental biology; Early embryogenesis; Gene regulation; LINE 1 L1 retrotransposon; Reverse transcriptase

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; NEVIRAPINE; RNA DIRECTED DNA POLYMERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; ENZYME INHIBITION; EUKARYOTE; FEMALE; GENE CONTROL; GENE EXPRESSION; LINE 1 RETROTRANSPOSON; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; PROTEIN FUNCTION; RETROPOSON; RETROVIRUS; ZYGOTE;

ANIMALS; ANIMALS, NEWBORN; BLASTOCYST; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MALE; MICE; MICE, INBRED STRAINS; MICROINJECTIONS; OLIGONUCLEOTIDES, ANTISENSE; OOCYTES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; TRANSCRIPTION, GENETIC;

ANIMALIA; EUKARYOTA; MURINAE;

EID: 32944476464     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrd.20423     Document Type: Article

References (34)

1. Brouha B, Schustak J, Badge RM, Lutz-Prigge S, Parley AH, Moran JV, Kazazian HH, Jr. 2003. Hot Lis account for the bulk of retrotransposition in the human population. Proc Natl Acad Sci USA 100:5280-5285.
2. Deininger PL, Moran JV, Batzer MA, Kazazian HH. 2003. Mobile elements and mammalian genome evolution. Curr Op Gen Dev 13:651-658.
3. Di Marzo Veronese F, Copeland TD, De Vico AL, Rahman R, Oroszlan S, Gallo RC, Sarngadharan MG. 1986. Characterization of highly immunogenic p66/p51 as the reverse transcriptase of HTLV-III/LAV. Science 231:1289-1291.
4. Druker R, Whitelaw E. 2004. Retrotransposon-derived elements in the mammalian genome: A potential source of disease. J Inherit Metab Dis 27:319-330.
5. Evsikov AV, deVries WN, Peaston AE, Radford EE, Fancher KS, Chen FH, Blake JA, Bult CJ, Latham KE, Solter D, Knowles BB. 2004. Systems biology of the 2-cell mouse embryo. Cytogenet Genome Res 105:240-250.
6. Giordano R, Magnano AR, Zaccagnini G, Pittoggi C, Moscufo N, Lorenzini R, Spadafora C. 2000. Reverse transcriptase activity in mature spermatozoa of mouse. J Cell Biol 148:1107-1113.
7. Han JS, Szak ST, Boeke JD. 2004. Transcriptional disruption by the L1 retrotransposon and implications for mammalian transcriptomes. Nature 429:268-274.
8. International Human Genome Consortium. 2001. Initial sequencing and analysis of the human genome. Nature 409:860-921.
9. Kashkush K, Feldman M, Levy AA. 2003. Transcriptional activation of retrotransposons alters the expression of adjacent genes in wheat. Nature Gen 33:102-106.
10. Kigami D, Minami N, Takayama H, Imai H. 2003. MuERV-L, one of the earliest transcribed genes in mouse one-cell embryos. Biol Reprod 68:651-654.
11. Lander Es, Linton LM, Birren B, Nussbaum C, et al. 2001. Initial sequencing and analysis of the human genome. Nature 409:860-921.
12. Lane N, Dean W, Erhardt S, Hajkova P, Surani A, Walter J, Reik W. 2003. Resistance of IAPs to methylation reprogrammingmay provide a mechanism for epigenetic inheritance in the mouse. Genesis 35:88-93.
13. Mangiacasale R, Pittoggi C, Sciamanna I, Careddu A, Mattei E, Lorenzini R, Travaglini L, Landriscina M, Barone C, Nervi C, Lavia P, Spadafora C. 2003. Exposure of normal and transformed cells to nevirapine, a Reverse Transcriptase inhibitor, reduces cell growth and promotes differentiation. Oncogene 22:2750-2761.
14. Muotri AR, Chu VT, Marchetto MCN, Deng W, Moran JV, Gage FH. 2005. Somatic mosaicism in neural precursor cells mediated by L1 retrotransposition. Nature 435:903-910.
15. Naas TP, DeBerardinis RJ, Moran JV, Ostertag EM, Kingsmore SF, Seldin MF, Hayashizaki Y, Martin SL, Kazazian HH. 1998. An actively retrotransposing, novel subfamily of mouse L1 elements. EMBO J 17:590-597.
16. Nekrutenko A, Li WH. 2001. Transposable elements are found in a large number of human protein-coding genes. Trends Genet 17:619-621.
17. Orgel LE, Crick FH. 1980. Selfish DNA: The ultimate parasite. Nature 284:604-607.
18. Ostertag EM, Kazazian HH, Jr. 2001. Biology of mammalian L1 retrotransposons. Annu Rev Genet 35:501-538.
19. Ostertag EM, DeBerardinis RJ, Goodier JL, Zhang Y, Yang N, Gerton GL, Kazazian HH, Jr. 2002. A mouse model of human L1 retrotransposition. Nat Genet 32:655-660.
20. Packer AI, Manova K, Bacharova RF. 1993. A discrete LINE-1 transcript in mouse blastocysts. Dev Biol 157:281-283.
21. Peaston AE, Evsikov AV, Graber JH, de Vries WN, Holbrook AE, Solter D, Knowles BB. 2004. Retrotransposons regulate host genes in mouse oocytes and preimplantation embryos. Dev Cell 7:597-606.
22. Pittoggi C, Renzi L, Zaccagnini G, Cimini D, Degrassi F, Giordano R, Magnano AR, Lorenzini R, Lavia P, Spadafora C. 1999. A fraction of mouse sperm chromatin is organized in nucleosomal hypersensitive domains enriched in retroposon DNA. J Cell Sci 112:3537-3548.
23. Pittoggi C, Sciamanna I, Mattei E, Beraldi R, Lobascio AM, Mai A, Quaglia MG, Lorenzini R, Spadafora C. 2003. A role of endogenous reverse transcriptase in murine early embryo development. Mol Reprod Dev 66:225-236.
24. Poznanski AA, Calarco PG. 1991. The expression of intracisternal A particle genes in the pre-implantation mouse embryo. Dev Biol 143:271-281.
25. Prak ET, Dodson AW, Farkash EA, Kazazian HH, Jr. 2003. Tracking an embryonic L1 retrotransposition event. Proc Natl Acad Sci USA 100:1832-1837.
26. Pyra H, Boni J, Schupbach J. 1994. Ultrasensitive retrovirus detection by a reverse transcriptase assay based onproduct enhancement. Proc Natl Acad Sci USA 91:1544-1548.
27. Reik W, Dean W, Walter J. 2001. Epigenetic reprogramming in mammalian development. Science 293:1089-1093.
28. Schramke V, Allshire R. 2003. Hairpin RNAs and retrotransposon LTRs effect RNAi and chromatin-based gene silencing. Science 301:1069-1074.
29. Sciamanna I, Barberi L, Martire A, Pittoggi C, Beraldi R, Giordano R, Magnano AR, Hogdson C, Spadafora C. 2003. Sperm endogenous Reverse Transcriptase as mediator of new genetic information. Biochem Bioph Res Comm 312:1039-1046.
30. Sciamanna I, Landriscina M, Pittoggi C, Quirino M, Mearelli C, Beraldi R, Mattei E, Serafino A, Cassano A, Sinibaldi-Vallebona P, Garaci E, Barone C, Spadafora C. 2005. Inhibition of endogenous Reverse Transcriptase antagonizes human tumor growth. Oncogene 24:3923-3931.
31. Shapiro JA, von Sternberg R. 2005. Why repetitive DNA is essential to genome function. Biol Rev 80:1-24.
32. Spadafora C. 2004. Endogenous Reverse Transcriptase: A mediator of cell proliferation and differentiation. Cytogen Genome Res 105:346-350.
33. Svoboda P, Stein P, Anger M, Bernstein E, Hannon GJ, Schultz RM. 2004. RNAi and expression of retroposons MuERV-L and IAP in preimplantation mouse embryos. Dev Biol 269:276-285.
34. Whitelew E, Martin DIK. 2001. Retrotransposons as epigenetic mediators of phenotypic variation in mammals. Nature Gen 27:361-365.