N-methyl-D-aspartate-evoked adenosine and inosine release from neurons requires extracellular calcium

Canadian Journal of Physiology and Pharmacology

Volumn 87, Issue 10, 2009, Pages 850-858

  Zamzow, Christina R ^a   Bose, Ratna ^a   Parkinson, Fiona E ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Adenosine uptake; Calcium calmodulin kinase; Cultured neurons; Equilibrative nucleoside transporter; Ifenprodil; NVP AAM077

Indexed keywords

ADENOSINE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; DIZOCILPINE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; IFENPRODIL; INOSINE; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID; NUCLEOSIDE TRANSPORTER;

ANIMAL TISSUE; ARTICLE; BRAIN CELL; CALCIUM CELL LEVEL; CONTROLLED STUDY; EXCITOTOXICITY; EXTRACELLULAR CALCIUM; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENOSINE; ANIMALS; CALCIUM; CALCIUM SIGNALING; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CEREBRAL CORTEX; CHELATING AGENTS; DIZOCILPINE MALEATE; EGTAZIC ACID; EXCITATORY AMINO ACID ANTAGONISTS; INOSINE; N-METHYLASPARTATE; NEURONS; PIPERIDINES; PURINES; QUINOXALINES; RATS; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 70449097723     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/Y09-075     Document Type: Article

References (42)

1. Albensi, B.C. 2007. The NMDA receptor/ion channel complex: a drug target for modulating synaptic plasticity and excitotoxicity. Curr. Pharm. Des. 13(31): 3185-3194. doi:10.2174/138161207782341321. PMID:18045168.
2. Barria, A., and Malinow, R. 2005. NMDA receptor subunit composition controls synaptic plasticity by regulating binding to CaMKII. Neuron, 48(2): 289-301. doi:10.1016/j.neuron.2005.08.034. PMID:16242409. (Pubitemid 41476362)
3. 2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus. Neuropharmacology, 52(1): 60-70. doi:10.1016/j.neuropharm.2006.07.013. PMID:16904707.
4. 2+ overload and neuronal death in cultured rat cortical neurons. J. Neurovirol. 12(1): 17-24. doi:10.1080/ 13550280500516427. PMID:16595370.
5. Bresink, I., Benke, T.A., Collett, V.J., Seal, A.J., Parsons, C.G., Henley, J.M., and Collingridge, G.L. 1996. Effects of memantine on recombinant rat NMDA receptors expressed in HEK 293 cells. Br. J. Pharmacol. 119(2): 195-204. PMID:8886398.
6. Chen, Y., Graham, D.I., and Stone, T.W. 1992. Release of endogenous adenosine and its metabolites by the activation of NMDA receptors in the rat hippocampus in vivo. Br. J. Pharmacol. 106(3): 632-638. PMID:1354544.
7. Chen, P., Goldberg, D.E., Kolb, B., Lanser, M., and Benowitz, L.I. 2002. Inosine induces axonal rewiring and improves behavioral outcome after stroke. Proc. Natl. Acad. Sci. U.S.A. 99(13): 9031-9036. doi:10.1073/pnas.132076299. PMID:12084941.
8. Colbran, R.J. 2004. Targeting of calcium/calmodulin-dependent protein kinase II. Biochem. J. 378(Pt 1): 1-16. doi:10.1042/BJ20031547. PMID:14653781.
9. Craig, C.G., and White, T.D. 1993. N-mefhyl-D-aspartate- and non-N-methyl-D-aspartate-evoked adenosine release from rat cortical slices: distinct purinergic sources and mechanisms of release. J. Neurochem. 60(3): 1073-1080. doi:10.1111/j.1471-4159.1993.tb03256.x. PMID:7679722. (Pubitemid 23066729)
10. Dale, N., Pearson, T., and Frenguelli, B.G. 2000. Direct measurement of adenosine release during hypoxia in the CA1 region of the rat hippocampal slice. J. Physiol. 526(Pt 1): 143-155. doi:10.1111/j.1469-7793.2000.00143.x. PMID:10878107. (Pubitemid 30456097)
11. Frenguelli, B.G., Wigmore, G., Llaudet, E., and Dale, N. 2007. Temporal and mechanistic dissociation of ATP and adenosine release during ischaemia in the mammalian hippocampus. J. Neurochem. 101(5): 1400-1413. doi:10.1111/j.1471- 4159.2006.04425.x. PMID:17459147. (Pubitemid 46718811)
12. 2B N-methyl-D-aspartate receptors: Implications for studies of synaptic transmission. Mol. Pharmacol. 70(3): 1022-1032. doi:10.1124/mol.106.024042. PMID:16778008.
13. Hardingham, G.E., Fukunaga, Y., and Bading, H. 2002. Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways. Nat. Neurosci. 5(5): 405-414. PMID:11953750.
14. 2+/calmodulin-dependent protein kinase II revealed by electron microscopy. J. Cell Biol. 115(4): 1049-1060. doi:10.1083/jcb.115.4. 1049. PMID:1659571. (Pubitemid 21909952)
15. Kornhuber, J., Bormann, J., Hübers, M., Rusche, K., and Riederer, P. 1991. Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain study. Eur. J. Pharmacol. 206(4): 297-300. doi:10.1016/0922-4106(91)90113-V. PMID:1717296.
16. 2+/calmodulin-dependent kinases. J. Physiol. 584(Pt 3): 885-894. doi:10.1113/jphysiol.2007.137380. PMID:17884930. (Pubitemid 350031929)
17. Leonard, A.S., Lim, I.A., Hemsworth, D.E., Horne, M.C., and Hell, J.W. 1999. Calcium/calmodulin-dependent protein kinase II is associated with the N-methyl-D-aspartate receptor. Proc. Natl. Acad. Sci. U.S.A. 96(6): 3239-3244. doi:10.1073/pnas.96.6.3239. PMID:10077668.
18. Lindberg, B., Klenow, H., and Hansen, K. 1967. Some properties of partially purified mammalian adenosine kinase. J. Biol. Chem. 242(3): 350-356. PMID:4290214.
19. 1 receptor in a manner different from its classical agonists. Br. J. Pharmacol. 146(4): 604-611. doi:10.1038/sj.bjp.0706335. PMID:16086036.
20. Liu, Y., Wong, T.P., Aarts, M., Rooyakkers, A., Liu, L., Lai, T.W., et al. 2007. NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo. J. Neurosci. 27(11): 2846-2857. doi:10.1523/JNEUROSCI.0116-07.2007. PMID:17360906.
21. Lu, Y., Chung, H.J., Li, Y., and Rosenberg, P.A. 2003. NMDA receptor-mediated extracellular adenosine accumulation in rat forebrain neurons in culture is associated with inhibition of adenosine kinase. Eur. J. Neurosci. 17(6): 1213-1222. doi:10.1046/j.1460-9568.2003.02554.x. PMID:12670309.
22. 2+ signaling, cell death and stroke. Trends Neurosci. 29(2): 75-81. doi:10.1016/j.tins.2005.12.001. PMID:16376999.
23. 2B-containing NMDA receptors in cortical long-term potentiation and long-term depression. J. Neurosci. 24(36): 7821-7828. doi:10.1523/JNEUROSCI. 1697-04.2004. PMID:15356193. (Pubitemid 39215685)
24. Monaghan, D.T., and Larsen, H. 1997. NR1 and NR2 subunit contributions to N-methyl-D-aspartate receptor channel blocker pharmacology. J. Pharmacol. Exp. Ther. 280(2): 614-620. PMID:9023271.
25. Paes-de-Carvalho, R., Dias, B.V., Martins, R.A., Pereira, M.R., Portugal, C.C., and Lanfredi, C. 2005. Activation of glutamate receptors promotes a calcium-dependent and transporter-mediated release of purines in cultured avian retinal cells: possible involvement of calcium/calmodulin-dependent protein kinase II. Neurochem. INt. 46(6): 441-451. doi:10.1016/j.neuint.2004.12.005. PMID:15769546.
26. Palella, T.D., Andres, C.M., and Fox, I.H. 1980. Human placental adenosine kinase. Kinetic mechanism and inhibition. J. Biol. Chem. 255(11): 5264-5269. PMID:6246102.
27. Parkinson, F.E., and Geiger, J.D. 1996. Effects of iodotubercidin on adenosine kinase activity and nucleoside transport in DDT1 MF-2 smooth muscle cells. J. Pharmacol. Exp. Ther. 277(3): 1397-1401. PMID:8667202.
28. Parsons, C.G., Stöffler, A., and Danysz, W. 2007. Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system-too little activation is bad, too much is even worse. Neuropharmacology, 53(6): 699-723. doi:10.1016/j.neuropharm.2007.07.013. PMID:17904591. (Pubitemid 47532143)
29. Pedata, F., Pazzagli, M., and Pepeu, G. 1991. Endogenous adenosine release from hippocampal slices: excitatory amino acid agonists stimulate release, antagonists reduce the electrically-evoked release. Naunyn Schmiedebergs Arch. Pharmacol. 344(5): 538-543. doi:10.1007/BF00170649. PMID:1811170.
30. Sahin, B., Kansy, J.W., Nairn, A.C., Spychala, J., Ealick, S.E., Fienberg, A.A., et al. 2004. Molecular characterization of recombinant mouse adenosine kinase and evaluation as a target for protein phosphorylation. Eur. J. Biochem. 271(17): 3547-3555. doi:10.1111/j.1432-1033.2004.04291.x. PMID:15317590.
31. Shen, H., Chen, G.J., Harvey, B.K., Bickford, P.C., and Wang, Y. 2005. Inosine reduces ischemic brain injury in rats. Stroke, 36(3): 654-659. doi:10.1161/01.STR.0000155747.15679.04. PMID:15692110. (Pubitemid 40344173)
32. 1 adenosine receptor activation. Biochem. Pharmacol. 59(5): 477-483. doi:10.1016/S0006-2952(99)00350-0. PMID:10660114.
33. Sinor, J.D., Du, S., Venneti, S., Blitzblau, R.C., Leszkiewicz, D.N., Rosenberg, P.A., and Aizenman, E. 2000. NMDA and glutamate evoke excitotoxicity at distinct cellular locations in rat cortical neurons in vitro. J. Neurosci. 20(23): 8831-8837. PMID:11102491.
34. Stone, T.W. 2005. Adenosine, neurodegeneration and neuroprotection. Neurol. Res. 27(2): 161-168. doi:10.1179/016164105X21896. PMID:15829179.
35. 2B-containing NMDA receptors. Neuropharmacology, 53(1): 10-17. doi:10.1016/j.neuropharm.2007.04.015. PMID:17570444.
36. 2C subunit proteins. J. Neurochem. 68(2): 469-478. PMID:9003031. (Pubitemid 27044705)
37. Williams, K. 1993. Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors. Mol. Pharmacol. 44(4): 851-859. PMID:7901753.
38. Wong, E.H., Kemp, J.A., Priestley, T., Knight, A.R., Woodruff, G.N., and Iversen, L.L. 1986. The anticonvulsant MK-801 is a potent N-mefhyl-D-aspartate antagonist. Proc. Natl. Acad. Sci. U.S.A. 83(18): 7104-7108. doi:10.1073/pnas.83.18.7104. PMID:3529096.
39. Yamauchi, T., and Fujisawa, H. 1983. Purification and characterization of the brain calmodulin-dependent protein kinase (kinase II), which is involved in the activation of tryptophan 5-monooxygenase. Eur. J. Biochem. 132(1): 15-21. doi:10.1111/j.1432-1033.1983.tb07319.x. PMID:6840077.
40. Zamzow, C.R., Bose, R., and Parkinson, F.E. 2006. The effect of acidosis on adenosine release from cultured rat forebrain neurons. Brain Res. 1082(1): 23-31. doi:10.1016/j.brainres.2006.01.115. PMID:16516170.
41. Zamzow, C.R., Xiong, W., and Parkinson, F.E. 2008. Astrocytes affect the profile of purines released from cultured cortical neurons. J. Neurosci. Res. 86(12): 2641-2649. doi:10.1002/jnr.21718. PMID:18478552.
42. 2B subtype receptor in prefrontal long-term potentiation and contextual fear memory. Neuron, 47(6): 859-872. doi:10.1016/j.neuron.2005.08.014. PMID:16157280.