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Volumn 916, Issue 1-3, 2009, Pages 76-85

Molecular structure, lipophilicity, solubility, absorption, and polar surface area of novel anticoagulant agents

Author keywords

Direct inhibitors of thrombin; Factor Xa inhibitors; Lipophilicity; Molecular structure; Solubility; Solvent effect

Indexed keywords


EID: 70350733478     PISSN: 01661280     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.theochem.2009.09.011     Document Type: Article
Times cited : (40)

References (74)
  • 18
    • 70350717380 scopus 로고    scopus 로고
    • M.J. Frisch, G.W. Trucks, H.B. Schlegel, G.E. Scuseria, M.A. Robb, J.R. Cheeseman, Jr. J.A. Montgomery, T. Vreven, T.K.N. Kudin, J.C. Burant, J.M. Millam, S.S. Iyengar, J. Tomasi, V. Barone, B. Mennucci, M. Cossi, G. Scalmani, N. Rega, G.A. Petersson, H. Nakatsuji, M. Hada, M. Ehara, K. Toyota, R. Fukuda, J. Hasegawa, M. Ishida, T. Nakajima, Y. Honda, O. Kitao, H. Nakai, M. Klene, X. Li, J.E. Knox, H.P. Hratchian, J.B. Cross, C. Adamo, C. Jaramillo, R. Gomperts, R.E. Stratmann, O. Yazyev, A.J. Austin, R. Cammi, C. Pomelli, J.W. Ochterski, P.Y. Ayala, K. Morokuma, G.A. Voth, P. Salvador, J.J. Dannenberg, V.G. Zakrzewski, S. Dapprich, A.D. Daniels, M.C. Strain, O. Farkas, D.K. Malick, A.D. Rabuck, K. Raghavachari, J.B. Foresman, J.V. Ortiz, Q. Cui, A.G. Baboul, S. Clifford, J. Cioslowski, B.B. Stefanov, G. Liu, A. Liashenko, P. Piskorz, I. Komaromi, R.L. Martin, D.J. Fox, T. Keith, M.A. Al-Laham, C.Y. Peng, A. Nanayakkara, M. Challacombe, P.M.W. Gill, B. Johnson, W. Chen, M.W. Wong, C. G
    • M.J. Frisch, G.W. Trucks, H.B. Schlegel, G.E. Scuseria, M.A. Robb, J.R. Cheeseman, Jr. J.A. Montgomery, T. Vreven, T.K.N. Kudin, J.C. Burant, J.M. Millam, S.S. Iyengar, J. Tomasi, V. Barone, B. Mennucci, M. Cossi, G. Scalmani, N. Rega, G.A. Petersson, H. Nakatsuji, M. Hada, M. Ehara, K. Toyota, R. Fukuda, J. Hasegawa, M. Ishida, T. Nakajima, Y. Honda, O. Kitao, H. Nakai, M. Klene, X. Li, J.E. Knox, H.P. Hratchian, J.B. Cross, C. Adamo, C. Jaramillo, R. Gomperts, R.E. Stratmann, O. Yazyev, A.J. Austin, R. Cammi, C. Pomelli, J.W. Ochterski, P.Y. Ayala, K. Morokuma, G.A. Voth, P. Salvador, J.J. Dannenberg, V.G. Zakrzewski, S. Dapprich, A.D. Daniels, M.C. Strain, O. Farkas, D.K. Malick, A.D. Rabuck, K. Raghavachari, J.B. Foresman, J.V. Ortiz, Q. Cui, A.G. Baboul, S. Clifford, J. Cioslowski, B.B. Stefanov, G. Liu, A. Liashenko, P. Piskorz, I. Komaromi, R.L. Martin, D.J. Fox, T. Keith, M.A. Al-Laham, C.Y. Peng, A. Nanayakkara, M. Challacombe, P.M.W. Gill, B. Johnson, W. Chen, M.W. Wong, C. Gonzalez, J.A. Pople, Gaussian 03, Revision D.01, Gaussian, Inc., Wallingford CT, 2004.
  • 21
    • 0034387584 scopus 로고    scopus 로고
    • For a recent perspective, see
    • For a recent perspective, see: E.J. Baerends, Theor. Chem. Acc. 103 (2000) 265.
    • (2000) Theor. Chem. Acc , vol.103 , pp. 265
    • Baerends, E.J.1
  • 28
    • 70350713248 scopus 로고    scopus 로고
    • http://www.vcclab.org.
  • 33
    • 70350732078 scopus 로고    scopus 로고
    • http://www.molinspiration.com.
  • 35
    • 85052942579 scopus 로고    scopus 로고
    • Carloni P., and Alber F. (Eds), Wiley-VCH GmbH & Co. KGaA, Weinheim
    • In: Carloni P., and Alber F. (Eds). Quantum Medicinal Chemistry (2003), Wiley-VCH GmbH & Co. KGaA, Weinheim
    • (2003) Quantum Medicinal Chemistry
  • 37
    • 84870649266 scopus 로고    scopus 로고
    • Available from:, accessed May 2009
    • Protein Data Bank. Available from: http://www.rscb.org/pdb/ (accessed May 2009).
    • Protein Data Bank
  • 62
    • 70350720308 scopus 로고    scopus 로고
    • http://www.syrres.com/.
  • 65
    • 70350732077 scopus 로고    scopus 로고
    • Available from
    • EMEA File Xarelto. Available from: www.emea.europa.eu.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.