메뉴 건너뛰기




Volumn 18, Issue 7, 2009, Pages 804-814

Reversal of dopaminergic degeneration in a parkinsonian rat following micrografting of human bone marrow-derived neural progenitors

Author keywords

6 OHDA; c Fos; Dopamine; Human mesenchymal stem cells; Neuroprotection; Nigrostriatal system; Notch1; Parkinson's disease

Indexed keywords

AMPHETAMINE; CYCLOSPORIN; DOPAMINE; NOTCH1 RECEPTOR; NUCLEAR MATRIX PROTEIN; OXIDOPAMINE; PROTEIN C FOS; SEROTONIN; TYROSINE 3 MONOOXYGENASE;

EID: 70350686405     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368909X470801     Document Type: Article
Times cited : (61)

References (75)
  • 1
    • 0036432028 scopus 로고    scopus 로고
    • Persephin-overexpressing neural stem cells regulate the function of nigral dopaminergic neurons and prevent their degeneration in a model of Parkinson's disease
    • Akerud, P.; Holm, P. C.; Castelo-Branco, G.; Sousa, K.; Rodriguez, F. J.; Arenas, E. Persephin-overexpressing neural stem cells regulate the function of nigral dopaminergic neurons and prevent their degeneration in a model of Parkinson's disease. Mol. Cell. Neurosci. 21(2):205-222; 2002.
    • (2002) Mol. Cell. Neurosci. , vol.21 , Issue.2 , pp. 205-222
    • Akerud, P.1    Holm, P.C.2    Castelo-Branco, G.3    Sousa, K.4    Rodriguez, F.J.5    Arenas, E.6
  • 2
    • 0036703491 scopus 로고    scopus 로고
    • Remyelination of the rat spinal cord by transplantation of identified bone marrow stromal cells
    • Akiyama, Y.; Radtke, C.; Kocsis, J. D. Remyelination of the rat spinal cord by transplantation of identified bone marrow stromal cells. J. Neurosci. 22(15):6623-6630; 2002.
    • (2002) J. Neurosci. , vol.22 , Issue.15 , pp. 6623-6630
    • Akiyama, Y.1    Radtke, C.2    Kocsis, J.D.3
  • 3
    • 57449101862 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of neurally modified mesenchymal stem cells induced by epigenetic modifiers and neural stem cell environment
    • Alexanian, A. R.; Maiman, D. J.; Kurpad, S. N.; Gennarelli, T. A. In vitro and in vivo characterization of neurally modified mesenchymal stem cells induced by epigenetic modifiers and neural stem cell environment. Stem Cells Dev. 17(6):1123-1130; 2008.
    • (2008) Stem Cells Dev. , vol.17 , Issue.6 , pp. 1123-1130
    • Alexanian, A.R.1    Maiman, D.J.2    Kurpad, S.N.3    Gennarelli, T.A.4
  • 4
    • 0037235343 scopus 로고    scopus 로고
    • Therapeutic angiogenesis using autologous bone marrow stromal cells: Improved blood flow in a chronic limb ischemia model
    • Al-Khaldi, A.; Al-Sabti, H.; Galipeau, J.; Lachapelle, K. Therapeutic angiogenesis using autologous bone marrow stromal cells: Improved blood flow in a chronic limb ischemia model. Ann. Thorac. Surg. 75(1):204-209; 2003.
    • (2003) Ann. Thorac. Surg. , vol.75 , Issue.1 , pp. 204-209
    • Al-Khaldi, A.1    Al-Sabti, H.2    Galipeau, J.3    Lachapelle, K.4
  • 5
    • 0037728761 scopus 로고    scopus 로고
    • Postnatal bone marrow stromal cells elicit a potent VEGF-dependent neoangiogenic response in vivo
    • DOI 10.1038/sj.gt.3301934
    • Al-Khaldi, A.; Eliopoulos, N.; Martineau, D.; Lejeune, L.; Lachapelle, K.; Galipeau, J. Postnatal bone marrow stromal cells elicit a potent VEGF-dependent neoangiogenic response in vivo. Gene Ther. 10(8):621-629; 2003. (Pubitemid 36553607)
    • (2003) Gene Therapy , vol.10 , Issue.8 , pp. 621-629
    • Al-Khaldi, A.1    Eliopoulos, N.2    Martineau, D.3    Lejeune, L.4    Lachapelle, K.5    Galipeau, J.6
  • 6
    • 0027753815 scopus 로고
    • Trophism, transplantation, and animal models of Parkinson's disease
    • Bankiewicz, K.; Mandel, R. J.; Sofroniew, M. V. Trophism, transplantation, and animal models of Parkinson's disease. Exp. Neurol. 124(1):140-149; 1993.
    • (1993) Exp. Neurol. , vol.124 , Issue.1 , pp. 140-149
    • Bankiewicz, K.1    Mandel, R.J.2    Sofroniew, M.V.3
  • 7
    • 0027937973 scopus 로고
    • Reversal of hemiparkinsonian syndrome in nonhuman primates by amnion implantation into caudate nucleus
    • Bankiewicz, K. S.; Palmatier, M.; Plunkett, R. J.; Cummins, A.; Oldfield, E. H. Reversal of hemiparkinsonian syndrome in nonhuman primates by amnion implantation into caudate nucleus. J. Neurosurg. 81(6):869-876; 1994.
    • (1994) J. Neurosurg. , vol.81 , Issue.6 , pp. 869-876
    • Bankiewicz, K.S.1    Palmatier, M.2    Plunkett, R.J.3    Cummins, A.4    Oldfield, E.H.5
  • 8
    • 0028795044 scopus 로고
    • Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain
    • Beck, K. D.; Valverde, J.; Alexi, T.; Poulsen, K.; Moffat, B.; Vandlen, R. A.; Rosenthal, A.; Hefti, F. Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain. Nature 373(6512):339-341; 1995.
    • (1995) Nature , vol.373 , Issue.6512 , pp. 339-341
    • Beck, K.D.1    Valverde, J.2    Alexi, T.3    Poulsen, K.4    Moffat, B.5    Vandlen, R.A.6    Rosenthal, A.7    Hefti, F.8
  • 10
    • 33947514846 scopus 로고    scopus 로고
    • Basic fibroblast growth factor modulates density of blood vessels and preserves tight junctions in organotypic cortical cultures of mice: A new in vitro model of the blood-brain barrier
    • DOI 10.1523/JNEUROSCI.4033-06.2007
    • Bendfeldt, K.; Radojevic, V.; Kapfhammer, J.; Nitsch, C. Basic fibroblast growth factor modulates density of blood vessels and preserves tight junctions in organotypic cortical cultures of mice: A new in vitro model of the blood-brain barrier. J. Neurosci. 27(12):3260-3267; 2007. (Pubitemid 46474137)
    • (2007) Journal of Neuroscience , vol.27 , Issue.12 , pp. 3260-3267
    • Bendfeldt, K.1    Radojevic, V.2    Kapfhammer, J.3    Nitsch, C.4
  • 11
    • 0023225802 scopus 로고
    • Adrenal medulla grafts enhance recovery of striatal dopaminergic fibers
    • Bohn, M. C.; Cupit, L.; Marciano, F.; Gash, D. M. Adrenal medulla grafts enhance recovery of striatal dopaminergic fibers. Science 237(4817):913-916; 1987.
    • (1987) Science , vol.237 , Issue.4817 , pp. 913-916
    • Bohn, M.C.1    Cupit, L.2    Marciano, F.3    Gash, D.M.4
  • 14
    • 33746424373 scopus 로고    scopus 로고
    • Mesenchymal stem cells as trophic mediators
    • Caplan, A. I.; Dennis, J. E. Mesenchymal stem cells as trophic mediators. J. Cell. Biochem. 98(5):1076-1084; 2006.
    • (2006) J. Cell. Biochem. , vol.98 , Issue.5 , pp. 1076-1084
    • Caplan, A.I.1    Dennis, J.E.2
  • 15
    • 0019982182 scopus 로고
    • Nerve fiber growth on defined hydrogel substrates
    • Carbonetto, S. T.; Gruver, M. M.; Turner, D. C. Nerve fiber growth on defined hydrogel substrates. Science 216(4548):897-899; 1982.
    • (1982) Science , vol.216 , Issue.4548 , pp. 897-899
    • Carbonetto, S.T.1    Gruver, M.M.2    Turner, D.C.3
  • 16
    • 1642319466 scopus 로고    scopus 로고
    • Combination therapy of stroke in rats with a nitric oxide donor and human bone marrow stromal cells enhances angiogenesis and neurogenesis
    • DOI 10.1016/j.brainres.2003.11.080, PII S0006899304001167
    • Chen, J.; Li, Y.; Zhang, R.; Katakowski, M.; Gautam, S. C.; Xu, Y.; Lu, M.; Zhang, Z.; Chopp, M. Combination therapy of stroke in rats with a nitric oxide donor and human bone marrow stromal cells enhances angiogenesis and neurogenesis. Brain Res. 1005(1-2):21-28; 2004. (Pubitemid 38388396)
    • (2004) Brain Research , vol.1005 , Issue.1-2 , pp. 21-28
    • Chen, J.1    Li, Y.2    Zhang, R.3    Katakowski, M.4    Gautam, S.C.5    Xu, Y.6    Lu, M.7    Zhang, Z.8    Chopp, M.9
  • 17
    • 0037418936 scopus 로고    scopus 로고
    • Intravenous administration of human bone marrow stromal cells induces angio-genesis in the ischemic boundary zone after stroke in rats
    • Chen, J.; Zhang, Z. G.; Li, Y.; Wang, L.; Xu, Y. X.; Gautam, S. C.; Lu, M.; Zhu, Z.; Chopp, M. Intravenous administration of human bone marrow stromal cells induces angio-genesis in the ischemic boundary zone after stroke in rats. Circ. Res. 92(6):692-699; 2003.
    • (2003) Circ. Res. , vol.92 , Issue.6 , pp. 692-699
    • Chen, J.1    Zhang, Z.G.2    Li, Y.3    Wang, L.4    Xu, Y.X.5    Gautam, S.C.6    Lu, M.7    Zhu, Z.8    Chopp, M.9
  • 20
    • 34047118680 scopus 로고    scopus 로고
    • Generating neuron-like cells from BM-derived mesenchymal stromal cells in vitro
    • Choong, P. F.; Mok, P. L.; Cheong, S. K.; Leong, C. F.; Then, K. Y. Generating neuron-like cells from BM-derived mesenchymal stromal cells in vitro. Cytotherapy 9(2): 170-183; 2007.
    • (2007) Cytotherapy , vol.9 , Issue.2 , pp. 170-183
    • Choong, P.F.1    Mok, P.L.2    Cheong, S.K.3    Leong, C.F.4    Then, K.Y.5
  • 21
    • 0013278301 scopus 로고    scopus 로고
    • Treatment of neural injury with marrow stromal cells
    • DOI 10.1016/S1474-4422(02)00040-6
    • Chopp, M.; Li, Y. Treatment of neural injury with marrow stromal cells. Lancet Neurol. 1(2):92-100; 2002. (Pubitemid 37163494)
    • (2002) Lancet Neurology , vol.1 , Issue.2 , pp. 92-100
    • Chopp, M.1    Li, Y.2
  • 22
    • 33845534557 scopus 로고    scopus 로고
    • Transplants of human mesenchymal stem cells improve functional recovery after spinal cord injury in the rat
    • Cizkova, D.; Rosocha, J.; Vanicky, I.; Jergova, S.; Cizek, M. Transplants of human mesenchymal stem cells improve functional recovery after spinal cord injury in the rat. Cell. Mol. Neurobiol. 26(7-8):1167-1180; 2006.
    • (2006) Cell. Mol. Neurobiol. , vol.26 , Issue.7-8 , pp. 1167-1180
    • Cizkova, D.1    Rosocha, J.2    Vanicky, I.3    Jergova, S.4    Cizek, M.5
  • 23
    • 0033374356 scopus 로고    scopus 로고
    • Differential effects of glial cell line-derived neurotrophic factor (GDNF) in the striatum and substantia nigra of the aged parkinsonian rat
    • Connor, B.; Kozlowski, D. A.; Schallert, T.; Tillerson, J. L.; Davidson, B. L.; Bohn, M. C. Differential effects of glial cell line-derived neurotrophic factor (GDNF) in the striatum and substantia nigra of the aged parkinsonian rat. Gene Ther. 6(12):1936-1951; 1999.
    • (1999) Gene Ther. , vol.6 , Issue.12 , pp. 1936-1951
    • Connor, B.1    Kozlowski, D.A.2    Schallert, T.3    Tillerson, J.L.4    Davidson, B.L.5    Bohn, M.C.6
  • 24
    • 32644434557 scopus 로고    scopus 로고
    • Human mesenchymal stem cell subpopulations express a variety of neuro-regulatory molecules and promote neuronal cell survival and neuritogenesis
    • Crigler, L.; Robey, R. C.; Asawachaicharn, A.; Gaupp, D.; Phinney, D. G. Human mesenchymal stem cell subpopulations express a variety of neuro-regulatory molecules and promote neuronal cell survival and neuritogenesis. Exp. Neurol. 198(1):54-64; 2006.
    • (2006) Exp. Neurol. , vol.198 , Issue.1 , pp. 54-64
    • Crigler, L.1    Robey, R.C.2    Asawachaicharn, A.3    Gaupp, D.4    Phinney, D.G.5
  • 25
    • 33845489970 scopus 로고    scopus 로고
    • Insights into autotransplantation: The unexpected discovery of specific induction systems in bone marrow stromal cells
    • Dezawa, M. Insights into autotransplantation: The unexpected discovery of specific induction systems in bone marrow stromal cells. Cell. Mol. Life Sci. 63(23):2764-2772; 2006.
    • (2006) Cell. Mol. Life Sci. , vol.63 , Issue.23 , pp. 2764-2772
    • Dezawa, M.1
  • 27
    • 0035783938 scopus 로고    scopus 로고
    • Sciatic nerve regeneration in rats induced by transplantation of in vitro differentiated bone-marrow stromal cells
    • Dezawa, M.; Takahashi, I.; Esaki, M.; Takano, M.; Sawada, H. Sciatic nerve regeneration in rats induced by transplantation of in vitro differentiated bone-marrow stromal cells. Eur. J. Neurosci. 14(11):1771-1776; 2001.
    • (2001) Eur. J. Neurosci. , vol.14 , Issue.11 , pp. 1771-1776
    • Dezawa, M.1    Takahashi, I.2    Esaki, M.3    Takano, M.4    Sawada, H.5
  • 28
    • 0023813332 scopus 로고
    • Graft-derived recovery from 6-OHDA lesions: Specificity of ventral mesencephalic graft tissues
    • Dunnett, S. B.; Hernandez, T. D.; Summerfield, A.; Jones, G. H.; Arbuthnott, G. Graft-derived recovery from 6-OHDA lesions: Specificity of ventral mesencephalic graft tissues. Exp. Brain Res. 71(2):411-424; 1988.
    • (1988) Exp. Brain Res. , vol.71 , Issue.2 , pp. 411-424
    • Dunnett, S.B.1    Hernandez, T.D.2    Summerfield, A.3    Jones, G.H.4    Arbuthnott, G.5
  • 29
    • 37549042851 scopus 로고    scopus 로고
    • Human neural progenitor cells over-expressing IGF-1 protect dopamine neurons and restore function in a rat model of Parkinson's disease
    • Ebert, A. D.; Beres, A. J.; Barber, A. E.; Svendsen, C. N. Human neural progenitor cells over-expressing IGF-1 protect dopamine neurons and restore function in a rat model of Parkinson's disease. Exp. Neurol. 209(1):213-223; 2008.
    • (2008) Exp. Neurol. , vol.209 , Issue.1 , pp. 213-223
    • Ebert, A.D.1    Beres, A.J.2    Barber, A.E.3    Svendsen, C.N.4
  • 30
    • 33846011117 scopus 로고    scopus 로고
    • Striatal delivery of neurturin by CERE-120, an AAV2 vector for the treatment of dopaminergic neuron degeneration in Parkinson's disease
    • Gasmi, M.; Herzog, C. D.; Brandon, E. P.; Cunningham, J. J.; Ramirez, G. A.; Ketchum, E. T.; Bartus, R. T. Striatal delivery of neurturin by CERE-120, an AAV2 vector for the treatment of dopaminergic neuron degeneration in Parkinson's disease. Mol. Ther. 15(1):62-68; 2007.
    • (2007) Mol. Ther. , vol.15 , Issue.1 , pp. 62-68
    • Gasmi, M.1    Herzog, C.D.2    Brandon, E.P.3    Cunningham, J.J.4    Ramirez, G.A.5    Ketchum, E.T.6    Bartus, R.T.7
  • 31
    • 0025155482 scopus 로고
    • Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum
    • Graybiel, A. M.; Moratalla, R.; Robertson, H. A. Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum. Proc. Natl. Acad. Sci. USA 87(17):6912-6916; 1990.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , Issue.17 , pp. 6912-6916
    • Graybiel, A.M.1    Moratalla, R.2    Robertson, H.A.3
  • 32
    • 0025099780 scopus 로고
    • Loss of brainstem serotoninand substance P-containing neurons in Parkinson's disease
    • Halliday, G. M.; Blumbergs, P. C.; Cotton, R. G.; Blessing, W. W.; Geffen, L. B. Loss of brainstem serotoninand substance P-containing neurons in Parkinson's disease. Brain Res. 510(1):104-107; 1990.
    • (1990) Brain Res. , vol.510 , Issue.1 , pp. 104-107
    • Halliday, G.M.1    Blumbergs, P.C.2    Cotton, R.G.3    Blessing, W.W.4    Geffen, L.B.5
  • 34
    • 33750587812 scopus 로고    scopus 로고
    • Intravenous administration of glial cell line-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in the adult rat
    • Horita, Y.; Honmou, O.; Harada, K.; Houkin, K.; Hamada, H.; Kocsis, J. D. Intravenous administration of glial cell line-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in the adult rat. J. Neurosci. Res. 84(7):1495-1504; 2006.
    • (2006) J. Neurosci. Res. , vol.84 , Issue.7 , pp. 1495-1504
    • Horita, Y.1    Honmou, O.2    Harada, K.3    Houkin, K.4    Hamada, H.5    Kocsis, J.D.6
  • 35
    • 0141919606 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine (ecstasy) inhibits dyskinesia expression and normalizes motor activity in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-treated primates
    • Iravani, M. M.; Jackson, M. J.; Kuoppamaki, M.; Smith, L. A.; Jenner, P. 3,4-Methylenedioxymethamphetamine (ecstasy) inhibits dyskinesia expression and normalizes motor activity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- treated primates. J. Neurosci. 23(27):9107-9115; 2003.
    • (2003) J. Neurosci. , vol.23 , Issue.27 , pp. 9107-9115
    • Iravani, M.M.1    Jackson, M.J.2    Kuoppamaki, M.3    Smith, L.A.4    Jenner, P.5
  • 36
    • 0032579828 scopus 로고    scopus 로고
    • Serotonergic activity in the rat striatum after intrastriatal transplantation of fetal nigra as measured by microdialysis
    • DOI 10.1016/S0006-8993(97)01541-2, PII S0006899397015412
    • Ishida, Y.; Hashiguchi, H.; Todaka, K.; Kuwahara, I.; Ishizuka, Y.; Nakane, H.; Uchimura, D.; Nishimori, T.; Mitsuyama, Y. Serotonergic activity in the rat striatum after intrastriatal transplantation of fetal nigra as measured by microdialysis. Brain Res. 788(1-2):207-214; 1998. (Pubitemid 28202163)
    • (1998) Brain Research , vol.788 , Issue.1-2 , pp. 207-214
    • Ishida, Y.1    Hashiguchi, H.2    Todaka, K.3    Kuwahara, I.4    Ishizuka, Y.5    Nakane, H.6    Uchimura, D.7    Nishimori, T.8    Mitsuyama, Y.9
  • 39
    • 0032874061 scopus 로고    scopus 로고
    • Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
    • Kopen, G. C.; Prockop, D. J.; Phinney, D. G. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc. Natl. Acad. Sci. USA 96(19):10711-10716; 1999.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , Issue.19 , pp. 10711-10716
    • Kopen, G.C.1    Prockop, D.J.2    Phinney, D.G.3
  • 40
    • 0035282712 scopus 로고    scopus 로고
    • Gene therapy to the rescue in Parkinson's disease. Response from Kordower and Aebischer
    • Kordower, J. H.; Aebischer, P. Gene therapy to the rescue in Parkinson's disease. Response from Kordower and Aebischer. Trends Pharmacol. Sci. 22(3):105-106; 2001.
    • (2001) Trends Pharmacol. Sci. , vol.22 , Issue.3 , pp. 105-106
    • Kordower, J.H.1    Aebischer, P.2
  • 43
    • 0033767704 scopus 로고    scopus 로고
    • Delivery of a GDNF gene into the substantia nigra after a progressive 6-OHDA lesion maintains functional nigrostriatal connections
    • Kozlowski, D. A.; Connor, B.; Tillerson, J. L.; Schallert, T.; Bohn, M. C. Delivery of a GDNF gene into the substantia nigra after a progressive 6-OHDA lesion maintains functional nigrostriatal connections. Exp. Neurol. 166(1): 1-15; 2000.
    • (2000) Exp. Neurol. , vol.166 , Issue.1 , pp. 1-15
    • Kozlowski, D.A.1    Connor, B.2    Tillerson, J.L.3    Schallert, T.4    Bohn, M.C.5
  • 44
    • 0028349042 scopus 로고
    • Interactions of developing neurons with the extracellular matrix
    • Letourneau, P. C.; Condic, M. L.; Snow, D. M. Interactions of developing neurons with the extracellular matrix. J. Neurosci. 14(3 Pt. 1):915-928; 1994.
    • (1994) J. Neurosci. , vol.14 , Issue.3 PART 1 , pp. 915-928
    • Letourneau, P.C.1    Condic, M.L.2    Snow, D.M.3
  • 46
    • 0035909960 scopus 로고    scopus 로고
    • Intracerebral transplantation of bone marrow stromal cells in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
    • Li, Y.; Chen, J.; Wang, L.; Zhang, L.; Lu, M.; Chopp, M. Intracerebral transplantation of bone marrow stromal cells in a 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine mouse model of Parkinson's disease. Neurosci. Lett. 316(2):67-70; 2001.
    • (2001) Neurosci. Lett. , vol.316 , Issue.2 , pp. 67-70
    • Li, Y.1    Chen, J.2    Wang, L.3    Zhang, L.4    Lu, M.5    Chopp, M.6
  • 48
    • 8744253481 scopus 로고    scopus 로고
    • Marrow stromal cell transplantation after traumatic brain injury promotes cellular proliferation within the brain
    • DOI 10.1227/01.NEU.0000141042.14476.3C
    • Mahmood, A.; Lu, D.; Chopp, M. Marrow stromal cell transplantation after traumatic brain injury promotes cellular proliferation within the brain. Neurosurgery 55(5): 1185-1193; 2004. (Pubitemid 39525223)
    • (2004) Neurosurgery , vol.55 , Issue.5 , pp. 1185-1192
    • Mahmood, A.1    Lu, D.2    Chopp, M.3
  • 49
    • 0036922542 scopus 로고    scopus 로고
    • Intracerebral transplantation of marrow stromal cells cultured with neurotrophic factors promotes functional recovery in adult rats subjected to traumatic brain injury
    • Mahmood, A.; Lu, D.; Wang, L.; Chopp, M. Intracerebral transplantation of marrow stromal cells cultured with neurotrophic factors promotes functional recovery in adult rats subjected to traumatic brain injury. J. Neurotrauma 19(12):1609-1617; 2002. (Pubitemid 36026216)
    • (2002) Journal of Neurotrauma , vol.19 , Issue.12 , pp. 1609-1617
    • Mahmood, A.1    Lu, D.2    Wang, L.3    Chopp, M.4
  • 50
    • 38149130378 scopus 로고    scopus 로고
    • Comparison of the therapeutic potential of adult and embryonic neural precursor cells in a rat model of Parkinson disease
    • Muraoka, K.; Shingo, T.; Yasuhara, T.; Kameda, M.; Yuen, W. J.; Uozumi, T.; Matsui, T.; Miyoshi, Y.; Date, I. Comparison of the therapeutic potential of adult and embryonic neural precursor cells in a rat model of Parkinson disease. J. Neurosurg. 108(1):149-159; 2008.
    • (2008) J. Neurosurg. , vol.108 , Issue.1 , pp. 149-159
    • Muraoka, K.1    Shingo, T.2    Yasuhara, T.3    Kameda, M.4    Yuen, W.J.5    Uozumi, T.6    Matsui, T.7    Miyoshi, Y.8    Date, I.9
  • 51
    • 0034597430 scopus 로고    scopus 로고
    • Vascular niche for adult hippocampal neurogenesis
    • Palmer, T. D.; Willhoite, A. R.; Gage, F. H. Vascular niche for adult hippocampal neurogenesis. J. Comp. Neurol. 425(4):479-494; 2000.
    • (2000) J. Comp. Neurol. , vol.425 , Issue.4 , pp. 479-494
    • Palmer, T.D.1    Willhoite, A.R.2    Gage, F.H.3
  • 52
    • 0025123704 scopus 로고
    • Brain-type glucose transporter (GLUT-1) is selectively localized to the blood-brain barrier. Studies with quantitative western blotting and in situ hybridization
    • Pardridge, W. M.; Boado, R. J.; Farrell, C. R. Brain-type glucose transporter (GLUT-1) is selectively localized to the blood-brain barrier. Studies with quantitative western blotting and in situ hybridization. J. Biol. Chem. 265(29): 18035-18040; 1990.
    • (1990) J. Biol. Chem. , vol.265 , Issue.29 , pp. 18035-18040
    • Pardridge, W.M.1    Boado, R.J.2    Farrell, C.R.3
  • 53
    • 51849088599 scopus 로고    scopus 로고
    • Mesenchymal stem cells therapy exerts neuroprotection in a progressive animal model of Parkinson's disease
    • Park, H. J.; Lee, P. H.; Bang, O. Y.; Lee, G.; Ahn, Y. H. Mesenchymal stem cells therapy exerts neuroprotection in a progressive animal model of Parkinson's disease. J. Neurochem. 107(1):141-151; 2008.
    • (2008) J. Neurochem. , vol.107 , Issue.1 , pp. 141-151
    • Park, H.J.1    Lee, P.H.2    Bang, O.Y.3    Lee, G.4    Ahn, Y.H.5
  • 56
    • 0037451169 scopus 로고    scopus 로고
    • Further proof of the plasticity of adult stem cells and their role in tissue repair
    • Prockop, D. J. Further proof of the plasticity of adult stem cells and their role in tissue repair. J. Cell Biol. 160(6): 807-809; 2003.
    • (2003) J. Cell Biol. , vol.160 , Issue.6 , pp. 807-809
    • Prockop, D.J.1
  • 57
    • 33750706917 scopus 로고    scopus 로고
    • Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes
    • Roy, N. S.; Cleren, C.; Singh, S. K.; Yang, L.; Beal, M. F.; Goldman, S. A. Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes. Nat. Med. 12(11):1259-1268; 2006.
    • (2006) Nat. Med. , vol.12 , Issue.11 , pp. 1259-1268
    • Roy, N.S.1    Cleren, C.2    Singh, S.K.3    Yang, L.4    Beal, M.F.5    Goldman, S.A.6
  • 58
    • 0032874648 scopus 로고    scopus 로고
    • Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain
    • Sakurada, K.; Ohshima-Sakurada, M.; Palmer, T. D.; Gage, F. H. Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain. Development 126(18):4017-4026; 1999.
    • (1999) Development , vol.126 , Issue.18 , pp. 4017-4026
    • Sakurada, K.1    Ohshima-Sakurada, M.2    Palmer, T.D.3    Gage, F.H.4
  • 59
    • 0037106213 scopus 로고    scopus 로고
    • Neural cells derived from adult bone marrow and umbilical cord blood
    • Sanchez-Ramos, J. R. Neural cells derived from adult bone marrow and umbilical cord blood. J. Neurosci. Res. 69(6):880-893; 2002.
    • (2002) J. Neurosci. Res. , vol.69 , Issue.6 , pp. 880-893
    • Sanchez-Ramos, J.R.1
  • 60
    • 0024100420 scopus 로고
    • Serotonin in involuntary movement disorders
    • Sandyk, R.; Fisher, H. Serotonin in involuntary movement disorders. Int. J. Neurosci. 42(3-4):185-208; 1988.
    • (1988) Int. J. Neurosci. , vol.42 , Issue.3-4 , pp. 185-208
    • Sandyk, R.1    Fisher, H.2
  • 61
    • 0028220834 scopus 로고
    • Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: A combined retrograde tracing and immunocytochemical study in the rat
    • Sauer, H.; Oertel, W. H. Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: A combined retrograde tracing and immunocytochemical study in the rat. Neuroscience 59(2):401-415; 1994.
    • (1994) Neuroscience , vol.59 , Issue.2 , pp. 401-415
    • Sauer, H.1    Oertel, W.H.2
  • 62
    • 57449096327 scopus 로고    scopus 로고
    • Derivation of neural stem cells from mesenchymal stem cells: Evidence for a bipotential stem cell population
    • Shih, C. C.; Fu, L.; Zhu, L.; Huang, Y.; Lee, T. D.; Forman, S. J. Derivation of neural stem cells from mesenchymal stem cells: Evidence for a bipotential stem cell population. Stem Cells Dev. 17(6):1109-1121; 2008.
    • (2008) Stem Cells Dev. , vol.17 , Issue.6 , pp. 1109-1121
    • Shih, C.C.1    Fu, L.2    Zhu, L.3    Huang, Y.4    Lee, T.D.5    Forman, S.J.6
  • 63
    • 37649019741 scopus 로고    scopus 로고
    • Protection of dopamine neurons by bone marrow stromal cells
    • Shintani, A.; Nakao, N.; Kakishita, K.; Itakura, T. Protection of dopamine neurons by bone marrow stromal cells. Brain Res. 1186:48-55; 2007.
    • (2007) Brain Res. , vol.1186 , pp. 48-55
    • Shintani, A.1    Nakao, N.2    Kakishita, K.3    Itakura, T.4
  • 64
    • 0026689954 scopus 로고
    • Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and Nmethyl-4-phenylpyridinium ion toxicity: Involvement of the glutathione system
    • Spina, M. B.; Squinto, S. P.; Miller, J.; Lindsay, R. M.; Hyman, C. Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and Nmethyl-4-phenylpyridinium ion toxicity: Involvement of the glutathione system. J. Neurochem. 59(1):99-106; 1992.
    • (1992) J. Neurochem. , vol.59 , Issue.1 , pp. 99-106
    • Spina, M.B.1    Squinto, S.P.2    Miller, J.3    Lindsay, R.M.4    Hyman, C.5
  • 65
    • 0026039075 scopus 로고
    • Effects of 6-hydroxydopamine lesions of the nigrostriatal pathway on striatal serotonin innervation in adult rats
    • Takeuchi, Y.; Sawada, T.; Blunt, S.; Jenner, P.; Marsden, C. D. Effects of 6-hydroxydopamine lesions of the nigrostriatal pathway on striatal serotonin innervation in adult rats. Brain Res. 562(2):301-305; 1991.
    • (1991) Brain Res. , vol.562 , Issue.2 , pp. 301-305
    • Takeuchi, Y.1    Sawada, T.2    Blunt, S.3    Jenner, P.4    Marsden, C.D.5
  • 66
    • 0025809028 scopus 로고
    • Serotonergic sprouting in the neostriatum after intrastriatal transplantation of fetal ventral mesencephalon
    • Takeuchi, Y.; Sawada, T.; Blunt, S.; Jenner, P.; Marsden, C. D. Serotonergic sprouting in the neostriatum after intrastriatal transplantation of fetal ventral mesencephalon. Brain Res. 551(1-2):171-177; 1991.
    • (1991) Brain Res. , vol.551 , Issue.1-2 , pp. 171-177
    • Takeuchi, Y.1    Sawada, T.2    Blunt, S.3    Jenner, P.4    Marsden, C.D.5
  • 69
    • 33846436077 scopus 로고    scopus 로고
    • Fibroblast growth factor (FGF)-2 and FGF receptor 3 are required for the development of the substantia nigra, and FGF-2 plays a crucial role for the rescue of dopaminergic neurons after 6-hydroxydopamine lesion
    • DOI 10.1523/JNEUROSCI.4493-06.2007
    • Timmer, M.; Cesnulevicius, K.; Winkler, C.; Kolb, J.; Lipokatic-Takacs, E.; Jungnickel, J.; Grothe, C. Fibroblast growth factor (FGF)-2 and FGF receptor 3 are required for the development of the substantia nigra, and FGF-2 plays a crucial role for the rescue of dopaminergic neurons after 6-hydroxydopamine lesion. J. Neurosci. 27(3):459-471; 2007. (Pubitemid 46143751)
    • (2007) Journal of Neuroscience , vol.27 , Issue.3 , pp. 459-471
    • Timmer, M.1    Cesnulevicius, K.2    Winkler, C.3    Kolb, J.4    Lipokatic-Takacs, E.5    Jungnickel, J.6    Grothe, C.7
  • 70
    • 0036850818 scopus 로고    scopus 로고
    • Adult stem cells: Assessing the case for pluripotency
    • Verfaillie, C. M. Adult stem cells: Assessing the case for pluripotency. Trends Cell Biol. 12(11):502-508; 2002.
    • (2002) Trends Cell Biol. , vol.12 , Issue.11 , pp. 502-508
    • Verfaillie, C.M.1
  • 71
    • 0034663515 scopus 로고    scopus 로고
    • Adult rat and human bone marrow stromal cells differentiate into neurons
    • Woodbury, D.; Schwarz, E. J.; Prockop, D. J.; Black, I. B. Adult rat and human bone marrow stromal cells differentiate into neurons. J. Neurosci. Res. 61(4):364-370; 2000.
    • (2000) J. Neurosci. Res. , vol.61 , Issue.4 , pp. 364-370
    • Woodbury, D.1    Schwarz, E.J.2    Prockop, D.J.3    Black, I.B.4
  • 72
    • 9344222239 scopus 로고    scopus 로고
    • Studies on the differentiation of dopaminergic traits in human neural progenitor cells in vitro and in vivo
    • Yang, M.; Donaldson, A. E.; Marshall, C. E.; Shen, J.; Iacovitti, L. Studies on the differentiation of dopaminergic traits in human neural progenitor cells in vitro and in vivo. Cell Transplant. 13(5):535-547; 2004. (Pubitemid 39557433)
    • (2004) Cell Transplantation , vol.13 , Issue.5 , pp. 535-547
    • Yang, M.1    Donaldson, A.E.2    Marshall, C.E.3    Shen, J.4    Iacovitti, L.5
  • 73
    • 33845258753 scopus 로고    scopus 로고
    • Transplantation of human neural stem cells exerts neuroprotection in a rat model of Parkinson's disease
    • Yasuhara, T.; Matsukawa, N.; Hara, K.; Yu, G.; Xu, L.; Maki, M.; Kim, S. U.; Borlongan, C. V. Transplantation of human neural stem cells exerts neuroprotection in a rat model of Parkinson's disease. J. Neurosci. 26(48):12497-12511; 2006.
    • (2006) J. Neurosci. , vol.26 , Issue.48 , pp. 12497-12511
    • Yasuhara, T.1    Matsukawa, N.2    Hara, K.3    Yu, G.4    Xu, L.5    Maki, M.6    Kim, S.U.7    Borlongan, C.V.8
  • 74
    • 0035808592 scopus 로고    scopus 로고
    • Peripheral nerve regeneration along collagen filaments
    • DOI 10.1016/S0006-8993(00)03025-0, PII S0006899300030250
    • Yoshii, S.; Oka, M. Peripheral nerve regeneration along collagen filaments. Brain Res. 888(1):158-162; 2001. (Pubitemid 32056272)
    • (2001) Brain Research , vol.888 , Issue.1 , pp. 158-162
    • Yoshii, S.1    Oka, M.2
  • 75
    • 0036118625 scopus 로고    scopus 로고
    • Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats
    • Zhao, L. R.; Duan, W. M.; Reyes, M.; Keene, C. D.; Verfaillie, C. M.; Low, W. C. Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats. Exp. Neurol. 174(1):11-20; 2002.
    • (2002) Exp. Neurol. , vol.174 , Issue.1 , pp. 11-20
    • Zhao, L.R.1    Duan, W.M.2    Reyes, M.3    Keene, C.D.4    Verfaillie, C.M.5    Low, W.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.