Insights into autotransplantation: The unexpected discovery of specific induction systems in bone marrow stromal cells

Cellular and Molecular Life Sciences

Volumn 63, Issue 23, 2006, Pages 2764-2772

  Dezawa, M ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Cell therapy; Mesenchymal cell; Myogenic differentiation; Neuronal differentiation; Regenerative medicine; Schwann cell; Transdifferentiation; Transplantation

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CARDIOTOXIN; OXIDOPAMINE; PLATELET DERIVED GROWTH FACTOR; TACROLIMUS;

ADOPTIVE IMMUNOTHERAPY; AUTOTRANSPLANTATION; CELL DIFFERENTIATION; CELL ISOLATION; CELL TRANSPLANTATION; DEGENERATIVE DISEASE; EMBRYONIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; MESENCHYME CELL; MUSCLE ATROPHY; MUSCULAR DYSTROPHY; NONHUMAN; PARKINSON DISEASE; REVIEW; SCHWANN CELL; STROKE;

ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; CEREBROVASCULAR ACCIDENT; DISEASE MODELS, ANIMAL; HUMANS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, DUCHENNE; NEURONS; PARKINSON DISEASE; STROMAL CELLS; TRANSPLANTATION, AUTOLOGOUS;

ANIMALIA;

EID: 33845489970     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-006-6191-7     Document Type: Review

References (64)

1. Bischoff, R. (1994) The Satellite Cell and Muscle Regeneration. McGraw-Hill, New York.
2. Montarras, D., Morgan, J., Collins, C., Relaix, F., Zaffran, S., Cumano, A., Partridge, T. and Buckingham, M. (2005) Direct isolation of satellite cells for skeletal muscle regeneration. Science 309, 2064-2067.
3. Kawasaki, H., Mizuseki, K., Nishikawa, S., Kaneko, S., Kuwana, Y., Nakanishi, S., Nishikawa, S. I. and Sasai, Y. (2000) Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron 28, 31-40.
4. Reubinoff, B. E., Itsykson, P., Turetsky, T., Pera, M. F., Reinhartz, E., Itzik, A. and Ben-Hur, T. (2001) Neural progenitors from human embryonic stem cells. Nat. Biotechnol. 19, 1134-1140.
5. Watanabe, K., Kamiya, D., Nishiyama, A., Katayama, T., Nozaki, S., Kawasaki, H., Watanabe, Y., Mizuseki, K. and Sasai, Y. (2005) Directed differentiation of telencephalic precursors from embryonic stem cells. Nat. Neurosci. 8, 288-296.
6. Brustle, O., Spiro, A. C., Karram, K., Choudhary, K., Okabe, S. and McKay, R. D. (1997) In vitro-generated neural precursors participate in mammalian brain development. Proc. Natl. Acad. Sci. USA 94, 14809-14814.
7. Martinez-Serrano, A. and Bjorklund, A. (1997) Immortalized neural progenitor cells for CNS gene transfer and repair. Trends Neurosci. 20, 530-538.
8. Reynolds, B. A. and Weiss, S. (1996) Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell. Dev. Biol. 175, 1-13.
9. Snyder, E. Y. (1994) Grafting immortalized neurons to the CNS. Curr. Opin. Neurobiol. 4, 742-751.
10. Whittemore, S. R. and Snyder, E. Y. (1996) Physiological relevance and functional potential of central nervous system-derived cell lines. Mol. Neurobiol. 12, 13-38.
11. Goldman, S. A. (2004) Directed mobilization of endogenous neural progenitor cells: the intersection of stem cell biology and gene therapy. Curr. Opin. Mol. Ther. 6, 466-472.
12. Haas, S., Weidner, N. and Winkler, J. (2005) Adult stem cell therapy in stroke. Curr. Opin. Neurol. 18, 59-64.
13. Lindvall, O., Kokaia, Z. and Martinez-Serrano, A. (2004) Stem cell therapy for human neurodegenerative disorders - how to make it work. Nat. Med. 10 (Suppl.), S42-S50.
14. McBride, J. L., Behrstock, S. P., Chen, E. Y., Jakel, R. J., Siegel, I., Svendsen, C. N. and Kordower, J. H. (2004) Human neural stem cell transplants improve motor function in a rat model of Huntington's disease. J. Comp. Neurol. 475, 211-219.
15. Storch, A., Sabolek, M., Milosevic, J., Schwarz, S. C. and Schwarz, J. (2004) Midbrain-derived neural stem cells: from basic science to therapeutic approaches. Cell Tissue. Res. 318, 15-22.
16. Asakura, A., Seale, P., Girgis-Gabardo, A. and Rudnicki, M. A. (2002) Myogenic specification of side population cells in skeletal muscle. J. Cell Biol. 159, 123-134.
17. Dreyfus, P. A. Chretien, F., Chazaud, B., Kirova, Y., Caramelle, P., Garcia, L., Butler-Browne, G. and Gherardi, R. K. (2004) Adult bone marrow-derived stem cells in muscle connective tissue and satellite cell niches. Am. J. Pathol. 164, 773-779.
18. Polesskaya, A., Seale, P. and Rudnicki, M. A. (2003) Wnt signaling induces the myogenic specification of resident CD45+ adult stem cells during muscle regeneration. Cell 113, 841-852.
19. Torrente, Y., Camirand, G., Pisati, F., Belicchi, M., Rossi, B., Colombo, F., El Fahime, M., Caron, N. J., Issekutz, A. C., Constantin, G., Tremblay, J. P. and Bresolin, N. (2003) Identification of a putative pathway for the muscle homing of stem cells in a muscular dystrophy model. J. Cell Biol. 162, 511-520.
20. Ferrari, G., Cusella-De Angelis, G., Coletta, M., Paolucci, E., Stornaiuolo, A., Cossu, G. and Mavilio, F. (1998) Muscle regeneration by bone marrow-derived myogenic progenitors. Science 279, 1528-1530.
21. Suva, D., Garavaglia, G., Menetrey, J., Chapuis, B., Hoffmeyer, P., Bernheim, L. and Kindler, V. (2004) Non-hematopoietic human bone marrow contains long-lasting, pluripotential mesenchymal stem cells. J. Cell. Physiol. 198, 110-118.
22. Prockop, D. J. (1997) Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 276, 71-74.
23. Pittenger, M. F., Mackay, A. M., Beck, S. C., Jaiswal, R. K., Douglas, R., Mosca, J. D., Moorman, M. A., Simonetti, D. W., Craig, S. and Marshak, D. R. (1999) Multilineage potential of adult human mesenchymal stem cells. Science 284, 143-147.
24. Pittenger, M. F., Mosca, J. D. and McIntosh, K. R. (2000) Human mesenchymal stem cells: progenitor cells for cartilage, bone, fat and stroma. Curr. Top. Microbiol. Immunol. 251, 3-11.
25. Chopp, M., Zhang, X. H., Li, Y., Wang, L., Chen, J., Lu, D., Lu, M. and Rosenblum M (2000) Spinal cord injury in rat: treatment with bone marrow stromal cell transplantation. Neuroreport 11, 3001-3005.
26. Chopp, M. and Li, Y. (2002) Treatment of neural injury with marrow stromal cells. Lancet. Neurol. 1, 92-100.
27. Hofstetter, C. P., Schwarz, E. J., Hess, D., Widenfalk, J., El Manira, A., Prockop, D. J. and Olson, L. (2002) Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery. Proc. Natl. Acad. Sci. USA 99, 2199-2204.
28. Borlongan, C. V., Lind, J. G., Dillon-Carter, O., Yu, G., Hadman, M., Cheng, C., Carroll, J. and Hess, D. C. (2004) Bone marrow grafts restore cerebral blood flow and blood brain barrier in stroke rats. Brain Res. 1010, 108-116.
29. Munoz, J. R., Stoutenger, B. R., Robinson, A. P., Specs, J. L. and Prockop, D. J. (2005) Human stem/progenitor cells from bone marrow promote neurogenesis of endogenous neural stem cells in the hippocampus of mice. Proc. Natl. Acad. Sci. USA 102, 18171-18176.
30. Prockop, D. J. (2003) Further proof of the plasticity of adult stem cells and their role in tissue repair. J. Cell Biol. 160, 807-809.
31. McBeath, R., Pirone, D. M., Nelson, C. M., Bhadriraju, K. and Chen, C. S. (2004) Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev. Cell. 6, 483-495.
32. Mezey, E., Chandross, K. J., Harta, G., Maki, R. A. and McKercher, S. R. (2000) Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow. Science 290, 1779-1782.
33. Alvarez-Dolado, M., Pardal, R., Garcia-Verdugo, J. M., Fike, J. R. Lee, H. O., Pfeffer, K., Lois, C., Morrison, S. J. and Alvarez-Buylla, A. (2003) Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature 425, 968-973.
34. Terada, N., Hamazaki, T., Oka, M., Hoki, M., Mastalerz, D. M., Nakano, Y., Meyer, E. M., Morel, L., Petersen, B. E. and Scott, E. W. (2002) Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature 416, 542-545.
35. Makino, S., Fukuda, K., Miyoshi, S., Konishi, F., Kodama, H., Pan, J., Sano, M., Takahashi, T., Hori, S., Abe, H., Hata, J., Umezawa, A. and Ogawa, S. (1999) Cardiomyocytes can be generated from marrow stromal cells in vitro. J. Clin. Invest. 103, 697-705.
36. Choi, K. S., Shin, J. S., Lee, J. J., Kim, Y. S., Kim, S. B. and Kim, C. W. (2005) In vitro trans-differentiation of rat mesenchymal cells into insulin-producing cells by rat pancreatic extract. Biochem. Biophys. Res. Commun. 330, 1299-1305.
37. Wang, G., Bunnell, B. A., Painter, R. G., Quiniones, B. C., Tom, S., Lanson, N. A. Jr, Specs, J. L., Bertucci, D., Peister, A., Weiss, D. J., Valentine, V. G., Prockop, D. J. and Kolls, J. K. (2005) Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis. Proc. Natl. Acad. Sci. USA 102, 186-191.
38. Wang, P. P., Wang, J. H., Yan, Z. P., Hu, M. Y., Lau, G. K., Fan, S. T. and Luk, J. M. (2004) Expression of hepatocyte-like phenotypes in bone marrow stromal cells after HGF induction. Biochem. Biophys. Res. Commun. 320, 712-716.
39. Dezawa, M., Takahashi, I., Esaki, M., Takano, M. and Sawada, H. (2001) Sciatic nerve regeneration in rats induced by transplantation of in vitro differentiated bone-marrow stromal cells. Eur. J. Neurosci. 14, 1771-1776.
40. Dezawa, M., Kanno, H., Hoshino, M., Cho, H., Matsumoto, N., Itokazu, Y., Tajima, N., Yamada, H., Sawada, H., Ishikawa, H., Mimura, T., Kitada, M., Suzuki, Y. and Ide, C. (2004) Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation. J. Clin. Invest. 113, 1701-1710.
41. Dezawa, M., Ishikawa, H., Itokazu, Y., Yoshihara, T., Hoshino, M., Takeda, S., Ide, C. and Nabeshima, Y. (2005) Bone marrow stromal cells generate muscle cells and repair muscle degeneration. Science 309, 314-317.
42. Mimura, T., Dezawa, M., Kanno, H., Sawada, H. and Yamamoto, I. (2004) Peripheral nerve regeneration by transplantation of bone marrow stromal cell-derived Schwann cells in adult rats. J. Neurosurg. 101, 806-812.
43. Kamada, T., Koda, M., Dezawa, M., Yoshinaga, K., Hashimoto, M., Koshizuka, S., Nishio, Y., Moriya, H. and Yamazaki, M. (2005) Transplantation of bone marrow stromal cell-derived Schwann cells promotes axonal regeneration and functional recovery after complete transection of adult rat spinal cord. J. Neuropathol. Exp. Neurol. 64, 37-45.
44. Dezawa, M., Hoshino, M., Nabeshima, Y. and Ide, C. (2005) Marrow stromal cells: implications in health and disease in the nervous system. Curr. Mol. Med. 5, 723-732.
45. Dezawa, M., Hoshino, M. and Ide, C. (2005) Treatment of neurodegenerative diseases using adult bone marrow stromal cell-derived neurons. Expert Opin. Biol. Ther. 5, 427-435.
46. Pearse, D. D., Pereira, F. C., Marcillo, A. E., Bates, M. L., Berrocal, Y. A., Filbin, M. T. and Bunge, M. B. (2004) cAMP and Schwann cells promote axonal growth and functional recovery after spinal cord injury. Nat. Med. 10, 610-616.
47. Lundkvist, J. and Lendahl, U. (2001) Notch and the birth of glial cells. Trends Neurosci. 24, 492-494.
48. Gaiano, N., Nye, J. S. and Fishell, G. (2000) Radial glial identity is promoted by Notch1 signaling in the murine forebrain. Neuron 26, 395-404.
49. Morrison, S. J., Perez, S. E., Qiao, Z., Verdi, J. M., Hicks, C., Weinmaster, G. and Anderson, D. J. (2000) Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells. Cell 101, 499-510.
50. Jessen, K. R. and Mirsky, R. (2005) The origin and development of glial cells in peripheral nerves. Nat. Rev. Neurosci. 6, 671-682.
51. Shibata, T., Yamada, K., Watanabe, M., Ikenaka, K., Wada, K., Tanaka, K. and Inoue, Y. (1997) Glutamate transporter GLAST is expressed in the radial glia-astrocyte lineage of developing mouse spinal cord. J. Neurosci. 17, 9212-9219.
52. Yamasaki, M., Yamada, K., Furuya, S., Mitoma, J., Hirabayashi, Y. and Watanabe, M. (2001) 3-Phosphoglycerate dehydrogenase, a key enzyme for 1-serine biosynthesis, is preferentially expressed in the radial glia/astrocyte lineage and olfactory ensheathing glia in the mouse brain. J. Neurosci. 21, 7691-7704.
53. Kageyama, R., Ohtsuka, T., Hatakeyama, J. and Ohsawa, R. (2005) Roles of bHLH genes in neural stem cell differentiation. Exp. Cell. Res. 306, 343-348.
54. Yoon, K. and Gaiano, N. (2005) Notch signaling in the mammalian central nervous system: insights from mouse mutants. Nat Neurosci 8 709-715.
55. Taga, T. and Fukuda, S. (2005) Role of IL-6 in the neural stem cell differentiation. Clin. Rev. Allergy. Immunol. 28, 249-256.
56. Mimura, T., Dezawa, M., Kanno, H. and Yamamoto, I. (2005) Behavioral and histological evaluation of a focal cerebral infarction rat model transplanted with neurons induced from bone marrow stromal cells. J. Neuropathol. Exp. Neurol. 64, 1108-1117.
57. Chen, J., Sanberg, P. R., Li, Y., Wang, L., Lu, M., Willing, A. E., Sanchez-Ramos, J. and Chopp, M. (2001) Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats. Stroke 32, 2682-2688.
58. Toda, H., Takahashi, J., Iwakami, N., Kimura, T., Hoki, S., Mozumi-Kitamura, K., Ono, S. and Hashimoto, N. (2001) Grafting neural stem cells improved the impaired spatial recognition in ischemic rats. Neurosci. Lett. 316, 9-12.
59. Akerud, P., Alberch, J., Eketjall, S., Wagner, J. and Arenas, E. (1999) Differential effects of glial cell line-derived neurotrophic factor and neurturin on developing and adult substantia nigra dopaminergic neurons. J. Neurochem. 73, 70-78.
60. Yamada, H., Dezawa, M., Shimazu, S., Baba, M., Sawada, H., Kuroiwa, Y., Yamamoto, I. and Kanno, H. (2003) Transfer of the von Hippel-Lindau gene to neuronal progenitor cells in treatment for Parkinson's disease. Ann. Neurol. 54, 352-359.
61. Seale, P., Sabourin, L. A., Girgis-Gabardo, A., Mansouri, A., Gruss, P. and Rudnicki, M. A. (2000) Pax7 is required for the specification of myogenic satellite cells. Cell 102, 777-786.
62. Bhagavati, S. and Xu, W. (2005) Generation of skeletal muscle from transplanted embryonic stem cells in dystrophic mice. Biochem. Biophys. Res. Commun. 333, 644-649.
63. Rubio, D., Garcia-Castro, J., Martin, M. C., de la Fuente, R., Cigudosa, J. C., Lloyd, A. C. and Bernad, A. (2005) Spontaneous human adult stem cell transformation. Cancer Res. 65, 3035-3039.
64. Serakinci, N., Guldberg, P., Burns, J. S., Abdallah, B., Schrodder, H., Jensen, T. and Kassem, M. (2004) Adult human mesenchymal stem cell as a target for neoplastic transformation. Oncogene 23, 5095-5098.