Hsp70 inhibits aminoglycoside-induced hearing loss and cochlear hair cell death

Cell Stress and Chaperones

Volumn 14, Issue 4, 2009, Pages 427-437

  Taleb, Mona ^a   Brandon, Carlene S ^a   Lee, Fu Shing ^a   Harris, Kelly C ^a   Dillmann, Wolfgang H ^b   Cunningham, Lisa L ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aminoglycoside; Cochlea; Hair cell; Hearing loss; Kanamycin; Ototoxicity

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; CASPASE; CISPLATIN; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; KANAMYCIN; STRESS ACTIVATED PROTEIN KINASE; AMINOGLYCOSIDE; ANTIINFECTIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; EAR PROTECTION; ENZYME INHIBITION; EVOKED BRAIN STEM AUDITORY RESPONSE; FEMALE; GENE OVEREXPRESSION; HAIR CELL; HEARING LOSS; HEAT SHOCK; IN VITRO STUDY; INHIBITION KINETICS; MALE; MOUSE; NEWBORN; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL; PROTEIN INDUCTION; UPREGULATION; WILD TYPE; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; METABOLISM; TRANSGENIC MOUSE;

MUS;

AMINOGLYCOSIDES; ANIMALS; ANTI-BACTERIAL AGENTS; CASPASES; CELL DEATH; HAIR CELLS, AUDITORY; HEARING LOSS; HSP70 HEAT-SHOCK PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; MICE, TRANSGENIC;

EID: 70350514868     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1007/s12192-008-0097-2     Document Type: Article

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