Apoptosis of guinea pig cochlear hair cells following chronic aminoglycoside treatment

European Archives of Oto-Rhino-Laryngology

Volumn 255, Issue 3, 1998, Pages 127-131

  Nakagawa, T ^a   Yamane, H ^b   Takayama, M ^b   Sunami, K ^b   Nakai, Y ^b  

^a YODOGAWA CHRISTIAN HOSPITAL   (Japan)

^b School of Medicine   (Japan)

Author keywords

Aminoglycoside toxicity; Cochlea; Hair cell apoptosis; Nick end labeling

Indexed keywords

AMINOGLYCOSIDE; DNA FRAGMENT; KANAMYCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; COCHLEA; CONTROLLED STUDY; DNA STRAND BREAKAGE; GUINEA PIG; HAIR CELL; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL;

ANIMALS; ANTI-BACTERIAL AGENTS; APOPTOSIS; GUINEA PIGS; HAIR CELLS; KANAMYCIN;

EID: 0031952889     PISSN: 09374477     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004050050027     Document Type: Article

References (20)

1. Bright J, Khar J, Khar A (1994) Apoptosis: programmed cell death in health and disease. Biosci Rep 14:67-81
2. Corwin JT, Cotanche DA (1988) Regeneration of sensory hair cells after acoustic trauma. Science 240: 1772-1774
3. Cotanche DA (1987) Regeneration of hair cell stereociliary bundles in the chick cochleae following severe acoustic trauma. Hear Res 30: 181-196
4. Forge A (1985) Outer hair cell loss and supporting cell expansion following chronic gentamicin treatment. Hear Res 19 : 171-182
5. Forge A, Li L, Corwin JT, Nevill G (1993) Ultrastructural evidence for hair cell regeneration in the mammalian inner ear. Science 259 : 1616-1619
6. Gavrieli Y, Sherman Y, BenSasson WA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119 : 493-501
7. Hawkins JE, Johnson LG (1981) Histopathology of cochlear and vestibular ototoxicity in laboratory animals. In: Lerner SA, Matz GJ, Hawkins JE (eds) Aminoglycoside ototoxicity. Little, Brown, Boston, pp 175-195
8. Lenoir M, Vago P (1996) Morphological indications of hair cell neodifferentiation in the organ of Corti of amikacin treated rat pups. C R Acad Sci III 319 : 269-276
9. Li L, Forge A (1995) Two modes of hair cell loss from the vestibular sensory epithelia of the guinea pig inner ear. J Comp Neurol 355 : 405-417
10. Li L, Forge A (1997) Apoptotic death of hair cells. Br J Audiol 31 : 120
11. Marean GC, Burt JM, Beecher MD, Rubel EW (1993) Hair cell regeneration in the European starling (Stumus vulgaris): recovery of pure-tone detection thresholds. Hear Res 71 : 125-136
12. Nakagawa T, Yamane H, Shibata S, Nakai Y (1997) Gentamicin ototoxicity induced apoptosis of the vestibular hair cells of guinea pigs. Eur Arch Otorhinolaryngol 254 : 9-14
13. Nakagawa T, Yamane H. Shibata S, Sunami K, Nakai Y (1997) Cell death caused by the acute effects of aminoglycoside and zinc in the ampullary cristae of guinea pigs. Eur Arch Otorhinolaryngol 254 : 153-157
14. Nakagawa T, Yamane H, Shibata S, Takayama M, Sunami K, Nakai Y (1997) Two modes of auditory hair cell loss following acoustic overstimulation in the avian inner ear. ORL (in press)
15. Raphael Y, Altschuler RA (1991) Scar formation after drug-induced cochlear insult. Hear Res 51 : 173-184
16. Rayais BM, Rubel EW (1988) Hair cell regeneration after acoustic trauma in adult Coturnix quail. Science 240: 1774-1776
17. Romand R, Chardin S, Calvez SL (1996) The spontaneous appearance of hair cell-like cells in the mammalian cochlea following aminoglycoside ototoxicity. Neuroreport 8 : 133-137
18. Seale J, Lawson TA, Abbott PJ, Harmon B, Kerr JF (1975) An electronmicroscopic study of the model cell death induced by cancer chemotherapeutic agents in population of proliferating normal and neoplastic cells. J Pathol 116 : 129-138
19. Warchol ME, Lambert PR, Goldstein BJ, Forge A, Corwin JT (1993) Regenerative proliferation in inner ear sensory epithelia from adult guinea pigs and humans. Science 259 : 1619-1622
20. Wersall J (1981) Structural damage to the organ of Corti and the vestibular epithelia caused by aminoglycoside antibiotics in the guinea pig. In: Lerner SA, Matz GJ, Hawkins JE (eds) Aminoglycoside ototoxicity. Little, Brown, Boston, pp 197-214