The 1.5-Å structure of XplA-heme, an unusual cytochrome P450 heme domain that catalyzes reductive biotransformation of royal demolition explosive

Journal of Biological Chemistry

Volumn 284, Issue 41, 2009, Pages 28467-28475

  Sabbadin, Federico ^a   Jackson, Rosamond ^a   Haider, Kamran ^a   Tampi, Girish ^a   Turkenburg, Johan P ^a   Hart, Sam ^a   Bruce, Neil C ^a   Grogan, Gideon ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CLOSE PROXIMITY; CRYSTAL FORMS; CYTOCHROME P450; CYTOCHROMES P450; DIOXYGENS; ELECTRON DONORS; FLAVODOXIN; HEME DOMAIN; HEME IRON; NITRAMINES; REDOX PARTNERS; SIDE CHAINS; SIDE-CHAIN; SPACE GROUPS; STRUCTURAL ORGANIZATION; WATER MOLECULE; WILD TYPES;

CRYSTAL STRUCTURE; DEMOLITION; ENZYME ACTIVITY; EXPLOSIVES; HYDROGEN; NITROGEN REMOVAL; OXYGENATION; PORPHYRINS; WATER TREATMENT;

HEMOGLOBIN;

ALANINE; ASPARTIC ACID; CYTOCHROME P450; GLUTAMIC ACID; GLUTAMINE; HEME IRON PROTEIN; HEMOPROTEIN; IMIDAZOLE; METHIONINE; PROTEIN XPIA; SERINE; THREONINE; UNCLASSIFIED DRUG; CYCLONITE; EXPLOSIVE; HEME; ISOENZYME; TRIAZINE DERIVATIVE;

ARTICLE; BIOTRANSFORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HYDROPHOBICITY; LIGAND BINDING; MICROENVIRONMENT; NONHUMAN; OXIDATION; OXYGENATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE; RHODOCOCCUS; RHODOCOCCUS RHODOCHROUS; WILD TYPE; AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; OXIDATION REDUCTION REACTION; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BINDING SITES; BIOTRANSFORMATION; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 ENZYME SYSTEM; EXPLOSIVE AGENTS; HEME; HUMANS; ISOENZYMES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; TRIAZINES;

EID: 70350509061     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.031559     Document Type: Article

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