Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF

Journal of Molecular Biology

Volumn 311, Issue 1, 2001, Pages 101-110

  Cupp Vickery, Jill R ^a   Garcia, Carlos ^a   Hofacre, Andy ^a   McGee Estrada, Kathleen ^a  

^a CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

I helix cleft; Ketoconazole; P450; P450eryF; X ray structure

Indexed keywords

CYTOCHROME P450 ISOENZYME; ERGOSTEROL; KETOCONAZOLE;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DRUG EFFECT; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; LIGAND BINDING; LIVER INJURY; NONHUMAN; PRIORITY JOURNAL;

EID: 0035800617     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4803     Document Type: Article

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