Three epigenetic drugs up-regulate homeobox gene Rhox5 in cancer cells through overlapping and distinct molecular mechanisms

Molecular Pharmacology

Volumn 76, Issue 5, 2009, Pages 1072-1081

  Li, Qiang ^a   Bartlett, David L ^a   Gorry, Michael C ^a   O'Malley, Mark E ^a   Guo, Z Sheng ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ARSENIC TRIOXIDE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B; HISTONE H3; HISTONE H4; LYSINE; MESSENGER RNA; N (2 AMINOPHENYL) 4 (3 PYRIDINYLMETHOXYCARBONYLAMINOMETHYL)BENZAMIDE;

ACETYLATION; ARTICLE; BREAST CANCER; CANCER CELL; COLON CANCER; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; DRUG MECHANISM; DRUG POTENCY; EPIGENETICS; GENE; GENE EXPRESSION REGULATION; GENE INDUCTION; HOMEOBOX; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RHOX5 GENE; RHOX6 GENE; RHOX9 GENE; RHOXF1 GENE; RHOXF2 GENE; UPREGULATION; X CHROMOSOME;

ANIMALS; ARSENICALS; AZACITIDINE; BENZAMIDES; CELL LINE, TUMOR; DNA MODIFICATION METHYLASES; EPIGENESIS, GENETIC; GENES, HOMEOBOX; GROWTH INHIBITORS; HISTONE DEACETYLASE INHIBITORS; HOMEODOMAIN PROTEINS; HUMANS; MALE; MICE; OXIDES; PYRIDINES; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 70350459845     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.109.056291     Document Type: Article

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