OTEX, an androgen-regulated human member of the paired-like class of homeobox genes

Biochemical Journal

Volumn 366, Issue 1, 2002, Pages 367-375

  Geserick, Christoph ^a   Weiss, Bertram ^a   Schleuning, Wolf Dieter ^a   Haendler, Bernard ^a  

^a BAYER PHARMA AG   (Germany)

Author keywords

Evolution; Homeodomain; Nuclear protein; Ovary; Testis

Indexed keywords

AMINO ACIDS; ASSAYS; MUTAGENESIS; PROTEINS;

CELL LINES;

GENES;

ANDROGEN; HOMEODOMAIN PROTEIN; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMOSOME MAP; CONTROLLED STUDY; EPIDIDYMIS; GENE ACTIVITY; HOMEOBOX; HORMONAL REGULATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INTRON; MOLECULAR EVOLUTION; NUCLEOTIDE SEQUENCE; OTEX GENE; OVARY; PHYLOGENY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REPRODUCTION; TESTIS; TRANSACTIVATION; TWO HYBRID SYSTEM; X CHROMOSOME;

AMINO ACID SEQUENCE; ANDROGENS; BASE SEQUENCE; CELLS, CULTURED; CHROMOSOME MAPPING; CLONING, MOLECULAR; EPIDIDYMIS; FEMALE; HOMEODOMAIN PROTEINS; HUMANS; MALE; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUTATION; OVARY; PHYLOGENY; SEQUENCE HOMOLOGY, AMINO ACID; TESTIS; TISSUE DISTRIBUTION; TRANS-ACTIVATION (GENETICS); TUMOR CELLS, CULTURED; TWO-HYBRID SYSTEM TECHNIQUES; X CHROMOSOME;

EID: 0037103745     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20020399     Document Type: Article

References (41)

1. The homeodomain: A new face for the helix-turn-helix?
2. Homeodomain proteins
3. Pax-2 controls multiple steps of urogenital development
4. The LIM homeobox gene Lhx9 is essential for mouse gonad formation
5. Sexually dimorphic sterility phenotypes in Hoxa10-deficient mice
6. Abnormal uterine stromal and glandular function associated with maternal reproductive defects in Hoxa11 null mice
7. 50 paired-like genes founded the paired class
8. Irradiation selectively inhibits expression from the androgen-dependent Pem homeobox gene promoter in Sertoli cells
9. The oncofetal gene Pem encodes a homeobox and is regulated in primordial and pre-muscle stem cells
10. The Pem homeobox gene. Androgen-dependent and -independent promoters and tissue-specific alternative RNA splicing
11. Esx1, a novel X chromosome-linked homeobox gene expressed in mouse extraembryonic tissues and male germ cells
12. Spx1, a novel X-linked homeobox gene expressed during spermatogenesis
13. ESX1L, a novel X chromosome-linked human homeobox gene expressed in the placenta and testis
14. Psx, a novel murine homeobox gene expressed in placenta
15. Identification and characterization of Psx-2, a novel member of the Psx (placenta-specific homeobox) family
16. Gpbox (Psx2), a homeobox gene preferentially expressed in female germ cells at the onset of sexual dimorphism in mice
17. Normal reproductive and macrophage function in Pem homeobox-deficient mice
18. Normal gonadal development in mice lacking GPBOX, a homeobox protein expressed in germ cells at the onset of sexual dimorphism
19. Esx1 is an X-chromosome-imprinted regulator of placental development and fetal growth
20. Pax gene diversity in the basal cnidarian Acropora rnillepora (Cnidaria, Anthozoa): Implications for the evolution of the Pax gene family
21. Organization and expression of eukaryotic split genes coding for proteins
22. Generality of a functional initiator consensus sequence
23. New androgen response elements in the murine Pem promoter mediate selective transactivation
24. Nuclear targeting signal recognition: A key control point in nuclear transport?
25. Putative nuclear localization signals (NLS) in protein transcription factors
26. A homeodomain protein selectively expressed in noradrenergic tissue regulates transcription of neurotransmitter biosynthetic genes
27. Combined restriction landmark genomic scanning and virtual genome scans identify a novel human homeobox gene, ALX3, that is hypermethylated in neuroblastoma
28. The ALX4 homeobox gene is mutated in patients with ossification defects of the skull (foramina parietalia permagna, OMIM 168500)
29. Pseudoautosomal deletions encompassing a novel homeobox gene cause growth failure in idiopathic short stature and Turner syndrome
30. The Peru homeobox gene: Rapid evolution of the homeodomain, X chromosomal localization, and expression in reproductive tissues
31. Evolutionary EST analysis identifies rapidly evolving male reproductive proteins in Drosophila
32. A novel PF/PN motif inhibits nuclear localization and DNA binding activity of the ESX1 homeoprotein
33. Identification of a nuclear localization signal, RRMKWKK, in the homeodomain transcription factor PBX-1
34. Nuclear trafficking of photoreceptor protein crx: The targeting sequence and pathologic implications
35. Identification of domains mediating transcription activation, repression, and inhibition in the paired-related homeobox protein, Prx2 (S8)
36. Temporal regulation of a paired-like homeodomain repressor/TLE co-repressor complex and a related activator is required for pituitary organogenesis
37. Androgen-selective gene regulation in the prostate
38. Familial premature ovarian failure due to an interstitial deletion of the long arm of the X chromosome
39. Severe nasal clefting and abnormal embryonic apoptosis in Alx3/Alx4 double mutant mice
40. Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning
41. Nkx2.5 and Nkx2.6, homologs of Drosophila tinrnan, are required for development of the pharynx