Functional analysis of a unique troponin c mutation, gly159asp, that causes Familial dilated cardiomyopathy, studied in explanted heart muscle

Circulation: Heart Failure

Volumn 2, Issue 5, 2009, Pages 456-464

  Dyer, Emma C ^a   Jacques, Adam M ^a   Hoskins, Anita C ^b   Ward, Douglas G ^a   Gallon, Clare E ^a   Messer, Andrew E ^a   Kaski, Juan Pablo ^c   Burch, Michael ^a   Kentish, Jonathan C ^b   Marston, Steven B ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cardiomyopathy; Contractility; Heart failure

Indexed keywords

ASPARTIC ACID; CALCIUM; GLYCINE; TROPONIN C; TROPONIN I; TROPONIN T; ACTIN; RECOMBINANT PROTEIN; TROPOMYOSIN;

ARTICLE; CHILD; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; EXPLANT; HEART MUSCLE; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MUTATIONAL ANALYSIS; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; SKINNED MUSCLE FIBER; THIN FILAMENT; CYTOSKELETON; GENETICS; GENOTYPE; HEART CONTRACTION; METABOLISM; MUTATION; PATHOPHYSIOLOGY; PHENOTYPE; PHOSPHORYLATION; PROTEIN PROCESSING;

ACTINS; ASPARTIC ACID; CALCIUM; CARDIOMYOPATHY, DILATED; CHILD, PRESCHOOL; CYTOSKELETON; GENOTYPE; GLYCINE; HUMANS; MUTATION; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PHENOTYPE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; TROPOMYOSIN; TROPONIN C; TROPONIN I; TROPONIN T;

EID: 70350448975     PISSN: 19413289     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCHEARTFAILURE.108.818237     Document Type: Article

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