Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy: Ca2+ regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein

Circulation Research

Volumn 86, Issue 11, 2000, Pages 1146-1152

  Redwood, Charles ^a   Lohmann, Karin ^b   Bing, Wu ^b   Esposito, Giovanna M ^a   Elliott, Kathryn ^a   Abdulrazzak, Hassan ^b   Knott, Adam ^b   Purcell, Ian ^b   Marston, Steven ^b   Watkins, Hugh ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

Cardiac muscle; Familial hypertrophic cardiomyopathy; In vitro motility; Troponin T

Indexed keywords

ACTIN; CALCIUM; CONTRACTILE PROTEIN; MYOSIN ADENOSINE TRIPHOSPHATASE; MYOSIN BINDING PROTEIN C; MYOSIN HEAVY CHAIN; TROPOMYOSIN; TROPONIN C; TROPONIN I; TROPONIN T;

ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; FAMILIAL DISEASE; HEART MUSCLE; HYPERTROPHIC CARDIOMYOPATHY; IN VITRO STUDY; MUSCLE ISOMETRIC CONTRACTION; PRIORITY JOURNAL; REGULATORY MECHANISM; THIN FILAMENT;

EID: 0034625768     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.86.11.1146     Document Type: Article

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