Variability in the ratio of mutant to wildtype myosin heavy chain present in the soleus muscle of patients with familial hypertrophic cardiomyopathy. A new approach for the quantification of mutant to wildtype protein

FEBS Letters

Volumn 461, Issue 3, 1999, Pages 246-252

  Nier, Volker ^a   Schultz, Imke ^a   Brenner, Bernhard ^a   Forssmann, Wolf Georg ^b   Raida, Manfred ^b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Niedersachsisches Inst F P   (Germany)

Author keywords

Myosin heavy chain; Familiar hypertrophic cardiomyopathy; Mass spectrometry; Missense mutation

Indexed keywords

MYOSIN HEAVY CHAIN;

ARTICLE; CAPILLARY ZONE ELECTROPHORESIS; CONTROLLED STUDY; GENETIC VARIABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; HYPERTROPHIC CARDIOMYOPATHY; MASS SPECTROMETRY; MUTANT; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SOLEUS MUSCLE;

AMINO ACID SUBSTITUTION; CARDIOMYOPATHY, HYPERTROPHIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROPHORESIS, CAPILLARY; HETEROZYGOTE; HUMANS; MASS SPECTROMETRY; MUSCLE, SKELETAL; MYOSIN HEAVY CHAINS; PEPTIDE FRAGMENTS; POINT MUTATION; PROTEIN ISOFORMS;

EID: 0032716168     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)01433-7     Document Type: Article

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