Uniform encapsulation of stable protein nanoparticles produced by spray freezing for the reduction of burst release

Journal of Pharmaceutical Sciences

Volumn 94, Issue 1, 2005, Pages 56-69

  Leach, W Thomas ^a,b   Simpson, Dale T ^b   Val, Tibisay N ^b   Anuta, Efemona C ^b   Yu, Zhongshui ^a   Williams III, Robert O ^a   Johnston, Keith P ^b  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b The University of Texas at Austin   (United States)

Author keywords

Bovine serum albumin; Initial burst; Protein stability; Solid in oil in oil processing; Spray freezing into liquid process

Indexed keywords

BOVINE SERUM ALBUMIN; LIQUID NITROGEN; MICROSPHERE; MONOMER; NANOPARTICLE; POLYGLACTIN; POLYLACTIC ACID; PROTEIN;

ALPHA HELIX; ARTICLE; CONFOCAL MICROSCOPY; ENCAPSULATION; FREEZING; GEL PERMEATION CHROMATOGRAPHY; INFRARED SPECTROSCOPY; PARTICLE SIZE; POROSITY; PROTEIN AGGREGATION; PROTEIN DENATURATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; SCANNING ELECTRON MICROSCOPY; SOLID IN OIL IN OIL ENCAPSULATION; SPRAY FREEZING; SURFACE PROPERTY; ULTRASOUND;

EID: 12244253744     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.20209     Document Type: Article

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