MKK4/SEK1 is negatively regulated through a feedback loop involving the E3 ubiquitin ligase itch

Journal of Biological Chemistry

Volumn 284, Issue 43, 2009, Pages 29399-29404

  Ahn, Young Ho ^a   Kurie, Jonathan M ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEPHOSPHORYLATIONS; ENVIRONMENTAL STRESS; FEED-BACK LOOP; KINASE ACTIVITY; LIGASES; NEGATIVE FEEDBACK; PROTEASOMES; PROTEIN LEVEL; UBIQUITIN LIGASES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

AMINO ACIDS; DEGRADATION; FEEDBACK; PROTEINS;

ENZYMES;

MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEASOME; SORBITOL; UBIQUITIN PROTEIN LIGASE E3;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME DEGRADATION; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; UBIQUITINATION;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; PROTEASOME ENDOPEPTIDASE COMPLEX; SORBITOL; SWEETENING AGENTS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 70350353084     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.044958     Document Type: Article

References (35)

1. Chang, L., and Karin, M. (2001) Nature 410, 37-40
2. Raman, M., Chen, W., and Cobb, M. H. (2007) Oncogene 26, 3100-3112
3. Johnson, G. L., Dohlman, H. G., and Graves, L. M. (2005) Curr. Opin. Chem. Biol. 9, 325-331
4. Chen, W., White, M. A., and Cobb, M. H. (2002) J. Biol. Chem. 277, 49105-49110
5. Deacon, K., and Blank, J. L. (1997) J. Biol. Chem. 272, 14489-14496
6. Morrison, D. K., and Davis, R. J. (2003) Annu. Rev. Cell Dev. Biol. 19, 91-118
7. Owens, D. M., and Keyse, S. M. (2007) Oncogene 26, 3203-3213
8. Hunter, T. (2007) Mol. Cell 28, 730-738
9. Lu, Z., and Hunter, T. (2009) Annu. Rev. Biochem. 78, 435-475
10. Laine, A., and Ronai, Z. (2005) Sci. STKE. 2005, re5
11. Bernassola, F., Karin, M., Ciechanover, A., and Melino, G. (2008) Cancer Cell 14, 10-21
12. Nakayama, K. I., and Nakayama, K. (2006) Nat. Rev. Cancer 6, 369-381
13. Liu, W. H., and Lai, M. Z. (2005) Mol. Cell. Biol. 25, 1367-1378
14. Yamashita, M., Ying, S. X., Zhang, G. M., Li, C., Cheng, S. Y., Deng, C. X., and Zhang, Y. E. (2005) Cell 121, 101-113
15. Lu, Z., Xu, S., Joazeiro, C., Cobb, M. H., and Hunter, T. (2002) Mol. Cell 9, 945-956
16. Kuo, W. L., Duke, C. J., Abe, M. K., Kaplan, E. L., Gomes, S., and Rosner, M. R. (2004) J. Biol. Chem. 279, 23073-23081
17. Wang, Y., Ge, Q., Houston, D., Thorner, J., Errede, B., and Dohlman, H. G. (2003) J. Biol. Chem. 278, 22284-22289
18. Sobko, A., Ma, H., and Firtel, R. A. (2002) Dev. Cell 2, 745-756
19. Melino, G., Gallagher, E., Aqeilan, R. I., Knight, R., Peschiaroli, A., Rossi, M., Scialpi, F., Malatesta, M., Zocchi, L., Browne, G., Ciechanover, A., and Bernassola, F. (2008) Cell Death Differ. 15, 1103-1112
20. Perry, W. L., Hustad, C. M., Swing, D. A., O'Sullivan, T. N., Jenkins, N. A., and Copeland, N. G. (1998) Nat. Genet. 18, 143-146
21. Meza, R., Nuñez-Valdez, M. E., Sanchez, J., and Bravo, A. (1996) FEMS Microbiol. Lett. 145, 333-339
22. Yujiri, T., Ware, M., Widmann, C., Oyer, R., Russell, D., Chan, E., Zaitsu, Y., Clarke, P., Tyler, K., Oka, Y., Fanger, G. R., Henson, P., and Johnson, G. L. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 7272-7277
23. Xia, Y., Wu, Z., Su, B., Murray, B., and Karin, M. (1998) Genes Dev. 12, 3369-3381
24. Zheng, C., Xiang, J., Hunter, T., and Lin, A. (1999) J. Biol. Chem. 274, 28966-28971
25. Matsuzawa, A., Tseng, P. H., Vallabhapurapu, S., Luo, J. L., Zhang, W., Wang, H., Vignali, D. A., Gallagher, E., and Karin, M. (2008) Science 321, 663-668
26. Xia, Y., Wang, J., Xu, S., Johnson, G. L., Hunter, T., and Lu, Z. (2007) Mol. Cell. Biol. 27, 510-517
27. Xu, Z., Kukekov, N. V., and Greene, L. A. (2003) EMBO J. 22, 252-261
28. Gao, M., Labuda, T., Xia, Y., Gallagher, E., Fang, D., Liu, Y. C., and Karin, M. (2004) Science 306, 271-275
29. Gallagher, E., Gao, M., Liu, Y. C., and Karin, M. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 1717-1722
30. Rossi, M., Aqeilan, R. I., Neale, M., Candi, E., Salomoni, P., Knight, R. A., Croce, C. M., and Melino, G. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 12753-12758
31. Rossi, M., De Laurenzi, V., Munarriz, E., Green, D. R., Liu, Y. C., Vousden, K. H., Cesareni, G., and Melino, G. (2005) EMBO J. 24, 836-848
32. Heissmeyer, V., Macián, F., Im, S. H., Varma, R., Feske, S., Venuprasad, K., Gu, H., Liu, Y. C., Dustin, M. L., and Rao, A. (2004) Nat. Immunol. 5, 255-265
33. Qiu, L., Joazeiro, C., Fang, N., Wang, H. Y., Elly, C., Altman, Y., Fang, D., Hunter, T., and Liu, Y. C. (2000) J. Biol. Chem. 275, 35734-35737
34. Sundvall, M., Korhonen, A., Paatero, I., Gaudio, E., Melino, G., Croce, C. M., Aqeilan, R. I., and Elenius, K. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 4162-4167
35. Marchese, A., Raiborg, C., Santini, F., Keen, J. H., Stenmark, H., and Benovic, J. L. (2003) Dev. Cell 5, 709-722