메뉴 건너뛰기




Volumn 41, Issue 12, 2009, Pages 2599-2609

Organic cation/carnitine transporter OCTN3 is present in astrocytes and is up-regulated by peroxisome proliferators-activator receptor agonist

Author keywords

Astrocytes; Carnitine; OCTN transporters; Peroxisomes; PPAR

Indexed keywords

CARNITINE; ORGANIC CATION TRANSPORTER 2; ORGANIC CATION TRANSPORTER 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PIRINIXIC ACID; SODIUM;

EID: 70350342862     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2009.08.020     Document Type: Article
Times cited : (34)

References (64)
  • 1
    • 0033738423 scopus 로고    scopus 로고
    • Mitochondrial and peroxisomal targeting of 2-methylacyl-CoA racemase in humans
    • Amery L., Fransen M., De Nys K., Mannaerts G.P., and Van Veldhoven P.P. Mitochondrial and peroxisomal targeting of 2-methylacyl-CoA racemase in humans. J Lipid Res 41 (2000) 1752-1759
    • (2000) J Lipid Res , vol.41 , pp. 1752-1759
    • Amery, L.1    Fransen, M.2    De Nys, K.3    Mannaerts, G.P.4    Van Veldhoven, P.P.5
  • 2
    • 33745893228 scopus 로고    scopus 로고
    • The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer
    • Bak L.K., Schousboe A., and Waagepetersen H.S. The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer. J Neurochem 98 (2006) 641-653
    • (2006) J Neurochem , vol.98 , pp. 641-653
    • Bak, L.K.1    Schousboe, A.2    Waagepetersen, H.S.3
  • 3
    • 8644266719 scopus 로고    scopus 로고
    • Involvement of OCTN2 and B0,+ in the transport of carnitine through an in vitro model of the blood-brain barrier
    • Berezowski V., Miecz D., Marszalek M., Broer A., Broer S., Cecchelli R., and Nałe{ogonek}cz K.A. Involvement of OCTN2 and B0,+ in the transport of carnitine through an in vitro model of the blood-brain barrier. J Neurochem 91 (2004) 860-872
    • (2004) J Neurochem , vol.91 , pp. 860-872
    • Berezowski, V.1    Miecz, D.2    Marszalek, M.3    Broer, A.4    Broer, S.5    Cecchelli, R.6    Nałecz, K.A.7
  • 4
    • 0015447985 scopus 로고
    • Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures
    • Booher J., and Sensenbrenner M. Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures. Neurobiology 2 (1972) 97-105
    • (1972) Neurobiology , vol.2 , pp. 97-105
    • Booher, J.1    Sensenbrenner, M.2
  • 6
    • 0020376142 scopus 로고
    • Carnitine, carnitine acyltransferases, and rat brain function
    • Bresolin N., Freddo L., Vergani L., and Angelini C. Carnitine, carnitine acyltransferases, and rat brain function. Exp Neurol 78 (1982) 285-292
    • (1982) Exp Neurol , vol.78 , pp. 285-292
    • Bresolin, N.1    Freddo, L.2    Vergani, L.3    Angelini, C.4
  • 7
    • 33749247963 scopus 로고    scopus 로고
    • Cell surface F1Fo ATP synthase: a new paradigm?
    • Chi S.L., and Pizzo S.V. Cell surface F1Fo ATP synthase: a new paradigm?. Ann Med 38 (2006) 429-438
    • (2006) Ann Med , vol.38 , pp. 429-438
    • Chi, S.L.1    Pizzo, S.V.2
  • 10
    • 67349261714 scopus 로고    scopus 로고
    • PPAR-mediated activity of phthalates: a link to the obesity epidemic?
    • Desvergne B., Feige J.N., and Casals-Casas C. PPAR-mediated activity of phthalates: a link to the obesity epidemic?. Mol Cell Endocrinol 304 (2009) 43-48
    • (2009) Mol Cell Endocrinol , vol.304 , pp. 43-48
    • Desvergne, B.1    Feige, J.N.2    Casals-Casas, C.3
  • 11
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: nuclear control of metabolism
    • Desvergne B., and Wahli W. Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 20 (1999) 649-688
    • (1999) Endocr Rev , vol.20 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 12
    • 0037707488 scopus 로고    scopus 로고
    • Energy contribution of octanoate to intact rat brain metabolism measured by 13C nuclear magnetic resonance spectroscopy
    • Ebert D., Haller R.G., and Walton M.E. Energy contribution of octanoate to intact rat brain metabolism measured by 13C nuclear magnetic resonance spectroscopy. J Neurosci 23 (2003) 5928-5935
    • (2003) J Neurosci , vol.23 , pp. 5928-5935
    • Ebert, D.1    Haller, R.G.2    Walton, M.E.3
  • 13
    • 0029058992 scopus 로고
    • Peroxisomal and mitochondrial carnitine acetyltransferases of Saccharomyces cerevisiae are encoded by a single gene
    • Elgersma Y., van Roermund C.W., Wanders R.J., and Tabak H.F. Peroxisomal and mitochondrial carnitine acetyltransferases of Saccharomyces cerevisiae are encoded by a single gene. EMBO J 14 (1995) 3472-3479
    • (1995) EMBO J , vol.14 , pp. 3472-3479
    • Elgersma, Y.1    van Roermund, C.W.2    Wanders, R.J.3    Tabak, H.F.4
  • 14
    • 53149120665 scopus 로고    scopus 로고
    • Formation of eicosanoids, E2/D2 isoprostanes, and docosanoids following decapitation-induced ischemia, measured in high-energy-microwaved rat brain
    • Farias S.E., Basselin M., Chang L., Heidenreich K.A., Rapoport S.I., and Murphy R.C. Formation of eicosanoids, E2/D2 isoprostanes, and docosanoids following decapitation-induced ischemia, measured in high-energy-microwaved rat brain. J Lipid Res 49 (2008) 1990-2000
    • (2008) J Lipid Res , vol.49 , pp. 1990-2000
    • Farias, S.E.1    Basselin, M.2    Chang, L.3    Heidenreich, K.A.4    Rapoport, S.I.5    Murphy, R.C.6
  • 16
    • 16544394843 scopus 로고    scopus 로고
    • Translocation of Bax and Bid to mitochondria, endoplasmic reticulum and nuclear envelope: possible control points in apoptosis
    • Gajkowska B., Wojewodzka U., and Gajda J. Translocation of Bax and Bid to mitochondria, endoplasmic reticulum and nuclear envelope: possible control points in apoptosis. J Mol Histol 35 (2004) 11-19
    • (2004) J Mol Histol , vol.35 , pp. 11-19
    • Gajkowska, B.1    Wojewodzka, U.2    Gajda, J.3
  • 18
    • 0035576934 scopus 로고    scopus 로고
    • Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier
    • Huber J.D., Egleton R.D., and Davis T.P. Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier. Trends Neurosci 24 (2001) 719-725
    • (2001) Trends Neurosci , vol.24 , pp. 719-725
    • Huber, J.D.1    Egleton, R.D.2    Davis, T.P.3
  • 19
    • 33645280080 scopus 로고    scopus 로고
    • Functional expression of the organic cation/carnitine transporter 2 in rat astrocytes
    • Inazu M., Takeda H., Maehara K., Miyashita K., Tomoda A., and Matsumiya T. Functional expression of the organic cation/carnitine transporter 2 in rat astrocytes. J Neurochem 97 (2006) 424-434
    • (2006) J Neurochem , vol.97 , pp. 424-434
    • Inazu, M.1    Takeda, H.2    Maehara, K.3    Miyashita, K.4    Tomoda, A.5    Matsumiya, T.6
  • 20
    • 0035209172 scopus 로고    scopus 로고
    • Functional relevance of carnitine transporter OCTN2 to brain distribution of l-carnitine and acetyl-l-carnitine across the blood-brain barrier
    • Kido Y., Tamai I., Ohnari A., Sai Y., Kagami T., Nezu J., Nikaido H., Hashimoto N., Asano M., and Tsuji A. Functional relevance of carnitine transporter OCTN2 to brain distribution of l-carnitine and acetyl-l-carnitine across the blood-brain barrier. J Neurochem 79 (2001) 959-969
    • (2001) J Neurochem , vol.79 , pp. 959-969
    • Kido, Y.1    Tamai, I.2    Ohnari, A.3    Sai, Y.4    Kagami, T.5    Nezu, J.6    Nikaido, H.7    Hashimoto, N.8    Asano, M.9    Tsuji, A.10
  • 21
    • 40149101595 scopus 로고    scopus 로고
    • PPAR alpha mediates transcriptional upregulation of novel organic cation transporters-2 and -3 and enzymes involved in hepatic carnitine synthesis
    • Koch A., Konig B., Stangl G.I., and Eder K. PPAR alpha mediates transcriptional upregulation of novel organic cation transporters-2 and -3 and enzymes involved in hepatic carnitine synthesis. Exp Biol Med (Maywood) 233 (2008) 356-365
    • (2008) Exp Biol Med (Maywood) , vol.233 , pp. 356-365
    • Koch, A.1    Konig, B.2    Stangl, G.I.3    Eder, K.4
  • 23
    • 33846641782 scopus 로고    scopus 로고
    • Lipid-lowering drugs in the MPTP mouse model of Parkinson's disease: fenofibrate has a neuroprotective effect, whereas bezafibrate and HMG-CoA reductase inhibitors do not
    • Kreisler A., Gele P., Wiart J.F., Lhermitte M., Destee A., and Bordet R. Lipid-lowering drugs in the MPTP mouse model of Parkinson's disease: fenofibrate has a neuroprotective effect, whereas bezafibrate and HMG-CoA reductase inhibitors do not. Brain Res 1135 (2007) 77-84
    • (2007) Brain Res , vol.1135 , pp. 77-84
    • Kreisler, A.1    Gele, P.2    Wiart, J.F.3    Lhermitte, M.4    Destee, A.5    Bordet, R.6
  • 24
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during assembly of the head of bacteriophageT4
    • Laemmli U.K. Cleavage of structural proteins during assembly of the head of bacteriophageT4. Nature 227 (1970) 680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 26
    • 37349065551 scopus 로고    scopus 로고
    • Expression patterns of the organic cation/carnitine transporter family in adult murine brain
    • Lamhonwah A.M., Hawkins C.E., Tam C., Wong J., Mai L., and Tein I. Expression patterns of the organic cation/carnitine transporter family in adult murine brain. Brain Dev 30 (2008) 31-42
    • (2008) Brain Dev , vol.30 , pp. 31-42
    • Lamhonwah, A.M.1    Hawkins, C.E.2    Tam, C.3    Wong, J.4    Mai, L.5    Tein, I.6
  • 27
    • 0033517716 scopus 로고    scopus 로고
    • GFP-human high-affinity carnitine transporter OCTN2 protein: subcellular localization and functional restoration of carnitine uptake in mutant cell lines with the carnitine transporter defect
    • Lamhonwah A.M., and Tein I. GFP-human high-affinity carnitine transporter OCTN2 protein: subcellular localization and functional restoration of carnitine uptake in mutant cell lines with the carnitine transporter defect. Biochem Biophys Res Commun 264 (1999) 909-914
    • (1999) Biochem Biophys Res Commun , vol.264 , pp. 909-914
    • Lamhonwah, A.M.1    Tein, I.2
  • 28
    • 33744801418 scopus 로고    scopus 로고
    • Novel localization of OCTN1, an organic cation/carnitine transporter, to mammalian mitochondria
    • Lamhonwah A.M., and Tein I. Novel localization of OCTN1, an organic cation/carnitine transporter, to mammalian mitochondria. Biochem Biophys Res Commun 345 (2006) 1315-1325
    • (2006) Biochem Biophys Res Commun , vol.345 , pp. 1315-1325
    • Lamhonwah, A.M.1    Tein, I.2
  • 29
    • 33845335481 scopus 로고    scopus 로고
    • The import receptor Pex7p and the PTS2 targeting sequence
    • Lazarow P.B. The import receptor Pex7p and the PTS2 targeting sequence. Biochim Biophys Acta 1763 (2006) 1599-1604
    • (2006) Biochim Biophys Acta , vol.1763 , pp. 1599-1604
    • Lazarow, P.B.1
  • 32
    • 45549106857 scopus 로고    scopus 로고
    • A molecular switch for targeting between endoplasmic reticulum (ER) and mitochondria: conversion of a mitochondria-targeting element into an ER-targeting signal in DAKAP1
    • Ma Y., and Taylor S.S. A molecular switch for targeting between endoplasmic reticulum (ER) and mitochondria: conversion of a mitochondria-targeting element into an ER-targeting signal in DAKAP1. J Biol Chem 283 (2008) 11743-11751
    • (2008) J Biol Chem , vol.283 , pp. 11743-11751
    • Ma, Y.1    Taylor, S.S.2
  • 33
    • 23744497058 scopus 로고    scopus 로고
    • Regulation of testis-specific carnitine transporter (octn3) gene by proximal cis-acting elements Sp1 in mice
    • Maeda T., Hirayama M., Kobayashi D., and Tamai I. Regulation of testis-specific carnitine transporter (octn3) gene by proximal cis-acting elements Sp1 in mice. Biochem Pharmacol 70 (2005) 858-868
    • (2005) Biochem Pharmacol , vol.70 , pp. 858-868
    • Maeda, T.1    Hirayama, M.2    Kobayashi, D.3    Tamai, I.4
  • 34
    • 0033464868 scopus 로고    scopus 로고
    • Astrocytes couple synaptic activity to glucose utilization in the brain
    • Magistretti P.J., and Pellerin L. Astrocytes couple synaptic activity to glucose utilization in the brain. News Physiol Sci 14 (1999) 177-182
    • (1999) News Physiol Sci , vol.14 , pp. 177-182
    • Magistretti, P.J.1    Pellerin, L.2
  • 35
    • 1542283630 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha target genes
    • Mandard S., Muller M., and Kersten S. Peroxisome proliferator-activated receptor alpha target genes. Cell Mol Life Sci 61 (2004) 393-416
    • (2004) Cell Mol Life Sci , vol.61 , pp. 393-416
    • Mandard, S.1    Muller, M.2    Kersten, S.3
  • 36
    • 0030658022 scopus 로고    scopus 로고
    • Coordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPARalpha and PPARgamma activators
    • Martin G., Schoonjans K., Lefebvre A.M., Staels B., and Auwerx J. Coordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPARalpha and PPARgamma activators. J Biol Chem 272 (1997) 28210-28217
    • (1997) J Biol Chem , vol.272 , pp. 28210-28217
    • Martin, G.1    Schoonjans, K.2    Lefebvre, A.M.3    Staels, B.4    Auwerx, J.5
  • 37
    • 37249013935 scopus 로고    scopus 로고
    • Localization of organic cation/carnitine transporter (OCTN2) in cells forming the blood-brain barrier
    • Miecz D., Januszewicz E., Czeredys M., Hinton B., Berezowski V., Cecchelli R., and Nałe{ogonek}cz K.A. Localization of organic cation/carnitine transporter (OCTN2) in cells forming the blood-brain barrier. J Neurochem 104 (2008) 113-123
    • (2008) J Neurochem , vol.104 , pp. 113-123
    • Miecz, D.1    Januszewicz, E.2    Czeredys, M.3    Hinton, B.4    Berezowski, V.5    Cecchelli, R.6    Nałecz, K.A.7
  • 38
    • 0026021804 scopus 로고
    • Astrocytes, not neurons, produce docosahexaenoic acid (22:6 omega-3) and arachidonic acid (20:4 omega-6)
    • Moore S.A., Yoder E., Murphy S., Dutton G.R., and Spector A.A. Astrocytes, not neurons, produce docosahexaenoic acid (22:6 omega-3) and arachidonic acid (20:4 omega-6). J Neurochem 56 (1991) 518-524
    • (1991) J Neurochem , vol.56 , pp. 518-524
    • Moore, S.A.1    Yoder, E.2    Murphy, S.3    Dutton, G.R.4    Spector, A.A.5
  • 39
    • 0035870096 scopus 로고    scopus 로고
    • Na+- and Cl-coupled active transport of carnitine by the amino acid transporter ATB(0, +) from mouse colon expressed in HRPE cells and Xenopus oocytes
    • Nakanishi T., Hatanaka T., Huang W., Prasad P.D., Leibach F.H., Ganapathy M.E., and Ganapathy V. Na+- and Cl-coupled active transport of carnitine by the amino acid transporter ATB(0, +) from mouse colon expressed in HRPE cells and Xenopus oocytes. J Physiol 532 (2001) 297-304
    • (2001) J Physiol , vol.532 , pp. 297-304
    • Nakanishi, T.1    Hatanaka, T.2    Huang, W.3    Prasad, P.D.4    Leibach, F.H.5    Ganapathy, M.E.6    Ganapathy, V.7
  • 41
    • 61849180931 scopus 로고    scopus 로고
    • Marked differences in cholesterol synthesis between neurons and glial cells from postnatal rats
    • Nieweg K., Schaller H., and Pfrieger F.W. Marked differences in cholesterol synthesis between neurons and glial cells from postnatal rats. J Neurochem 109 (2009) 125-134
    • (2009) J Neurochem , vol.109 , pp. 125-134
    • Nieweg, K.1    Schaller, H.2    Pfrieger, F.W.3
  • 42
    • 46749151032 scopus 로고    scopus 로고
    • The emerging role of docosahexaenoic acid in neuroinflammation
    • Orr S.K., and Bazinet R.P. The emerging role of docosahexaenoic acid in neuroinflammation. Curr Opin Investig Drugs 9 (2008) 735-743
    • (2008) Curr Opin Investig Drugs , vol.9 , pp. 735-743
    • Orr, S.K.1    Bazinet, R.P.2
  • 43
    • 0018744514 scopus 로고
    • Paradoxical effects of clofibrate on liver and muscle metabolism in rats. Induction of myotonia and alteration of fatty acid and glucose oxidation
    • Paul H.S., and Adibi S.A. Paradoxical effects of clofibrate on liver and muscle metabolism in rats. Induction of myotonia and alteration of fatty acid and glucose oxidation. J Clin Invest 64 (1979) 405-412
    • (1979) J Clin Invest , vol.64 , pp. 405-412
    • Paul, H.S.1    Adibi, S.A.2
  • 44
    • 1642457265 scopus 로고    scopus 로고
    • Neuroenergetics: calling upon astrocytes to satisfy hungry neurons
    • Pellerin L., and Magistretti P.J. Neuroenergetics: calling upon astrocytes to satisfy hungry neurons. Neuroscientist 10 (2004) 53-62
    • (2004) Neuroscientist , vol.10 , pp. 53-62
    • Pellerin, L.1    Magistretti, P.J.2
  • 45
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29 (2001) e45
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 48
    • 0036088745 scopus 로고    scopus 로고
    • Organic cation/carnitine transporter, OCTN2, is differentially expressed in the adult rat epididymis
    • Rodriguez C.M., Labus J.C., and Hinton B.T. Organic cation/carnitine transporter, OCTN2, is differentially expressed in the adult rat epididymis. Biol Reprod 67 (2002) 314-319
    • (2002) Biol Reprod , vol.67 , pp. 314-319
    • Rodriguez, C.M.1    Labus, J.C.2    Hinton, B.T.3
  • 50
    • 0020473533 scopus 로고
    • Internal sequence repeats and the path of polypeptide in mitochondrial ADP/ATP translocase
    • Saraste M., and Walker J.E. Internal sequence repeats and the path of polypeptide in mitochondrial ADP/ATP translocase. FEBS Lett 144 (1982) 250-254
    • (1982) FEBS Lett , vol.144 , pp. 250-254
    • Saraste, M.1    Walker, J.E.2
  • 52
    • 17144449057 scopus 로고    scopus 로고
    • Identification of multispecific organic anion transporter 2 expressed predominantly in the liver
    • Sekine T., Cha S.H., Tsuda M., Apiwattanakul N., Nakajima N., Kanai Y., and Endou H. Identification of multispecific organic anion transporter 2 expressed predominantly in the liver. FEBS Lett 429 (1998) 179-182
    • (1998) FEBS Lett , vol.429 , pp. 179-182
    • Sekine, T.1    Cha, S.H.2    Tsuda, M.3    Apiwattanakul, N.4    Nakajima, N.5    Kanai, Y.6    Endou, H.7
  • 53
    • 0031777332 scopus 로고    scopus 로고
    • CSF levels of carnitine in children with meningitis, neurologic disorders, acute gastroenteritis, and seizure
    • Shinawi M., Gruener N., and Lerner A. CSF levels of carnitine in children with meningitis, neurologic disorders, acute gastroenteritis, and seizure. Neurology 50 (1998) 1869-1871
    • (1998) Neurology , vol.50 , pp. 1869-1871
    • Shinawi, M.1    Gruener, N.2    Lerner, A.3
  • 54
    • 0033588179 scopus 로고    scopus 로고
    • Cloning and functional expression of a human Na(+) and Cl(-)-dependent neutral and cationic amino acid transporter B(0+)
    • Sloan J.L., and Mager S. Cloning and functional expression of a human Na(+) and Cl(-)-dependent neutral and cationic amino acid transporter B(0+). J Biol Chem 274 (1999) 23740-23745
    • (1999) J Biol Chem , vol.274 , pp. 23740-23745
    • Sloan, J.L.1    Mager, S.2
  • 55
    • 9244252558 scopus 로고    scopus 로고
    • Membrane-associated and secreted genes in breast cancer
    • Stitziel N.O., Mar B.G., Liang J., and Westbrook C.A. Membrane-associated and secreted genes in breast cancer. Cancer Res 64 (2004) 8682-8687
    • (2004) Cancer Res , vol.64 , pp. 8682-8687
    • Stitziel, N.O.1    Mar, B.G.2    Liang, J.3    Westbrook, C.A.4
  • 56
    • 0026769928 scopus 로고
    • Targeting efficiencies of various permutations of the consensus C-terminal tripeptide peroxisomal targeting signal
    • Swinkels B.W., Gould S.J., and Subramani S. Targeting efficiencies of various permutations of the consensus C-terminal tripeptide peroxisomal targeting signal. FEBS Lett 305 (1992) 133-136
    • (1992) FEBS Lett , vol.305 , pp. 133-136
    • Swinkels, B.W.1    Gould, S.J.2    Subramani, S.3
  • 57
    • 33749860753 scopus 로고    scopus 로고
    • The endocrine disrupting chemical, diethylhexyl phthalate, activates MDR1 gene expression in human colon cancer LS174T cells
    • Takeshita A., Inagaki K., Igarashi-Migitaka J., Ozawa Y., and Koibuchi N. The endocrine disrupting chemical, diethylhexyl phthalate, activates MDR1 gene expression in human colon cancer LS174T cells. J Endocrinol 190 (2006) 897-902
    • (2006) J Endocrinol , vol.190 , pp. 897-902
    • Takeshita, A.1    Inagaki, K.2    Igarashi-Migitaka, J.3    Ozawa, Y.4    Koibuchi, N.5
  • 58
    • 0032493741 scopus 로고    scopus 로고
    • Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2
    • Tamai I., Ohashi R., Nezu J., Yabuuchi H., Oku A., Shimane M., Sai Y., and Tsuji A. Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2. J Biol Chem 273 (1998) 20378-20382
    • (1998) J Biol Chem , vol.273 , pp. 20378-20382
    • Tamai, I.1    Ohashi, R.2    Nezu, J.3    Yabuuchi, H.4    Oku, A.5    Shimane, M.6    Sai, Y.7    Tsuji, A.8
  • 59
    • 0034704135 scopus 로고    scopus 로고
    • Molecular and functional characterization of organic cation/carnitine transporter family in mice
    • Tamai I., Ohashi R., Nezu J.I., Sai Y., Kobayashi D., Oku A., Shimane M., and Tsuji A. Molecular and functional characterization of organic cation/carnitine transporter family in mice. J Biol Chem 275 (2000) 40064-40072
    • (2000) J Biol Chem , vol.275 , pp. 40064-40072
    • Tamai, I.1    Ohashi, R.2    Nezu, J.I.3    Sai, Y.4    Kobayashi, D.5    Oku, A.6    Shimane, M.7    Tsuji, A.8
  • 60
    • 33845310297 scopus 로고    scopus 로고
    • Targeting signals in peroxisomal membrane proteins
    • Van Ael E., and Fransen M. Targeting signals in peroxisomal membrane proteins. Biochim Biophys Acta 1763 (2006) 1629-1638
    • (2006) Biochim Biophys Acta , vol.1763 , pp. 1629-1638
    • Van Ael, E.1    Fransen, M.2
  • 61
    • 0033278397 scopus 로고    scopus 로고
    • Fatty acids, eicosanoids, and hypolipidemic agents regulate gene expression through direct binding to peroxisome proliferator activated receptors
    • Wahli W., Devchand P.R., IJpenberg A., and Desvergne B. Fatty acids, eicosanoids, and hypolipidemic agents regulate gene expression through direct binding to peroxisome proliferator activated receptors. Adv Exp Med Biol 447 (1999) 199-209
    • (1999) Adv Exp Med Biol , vol.447 , pp. 199-209
    • Wahli, W.1    Devchand, P.R.2    IJpenberg, A.3    Desvergne, B.4
  • 62
    • 4744371532 scopus 로고    scopus 로고
    • Peroxisomes, lipid metabolism, and peroxisomal disorders
    • Wanders R.J. Peroxisomes, lipid metabolism, and peroxisomal disorders. Mol Genet Metab 83 (2004) 16-27
    • (2004) Mol Genet Metab , vol.83 , pp. 16-27
    • Wanders, R.J.1
  • 63
    • 34249870602 scopus 로고    scopus 로고
    • Clofibrate-induced changes in the liver, heart, brain and white adipose lipid metabolome of Swiss-Webster mice
    • Wheelock C.E., Goto S., Hammock B.D., and Newman J.W. Clofibrate-induced changes in the liver, heart, brain and white adipose lipid metabolome of Swiss-Webster mice. Metabolomics 3 (2007) 137-145
    • (2007) Metabolomics , vol.3 , pp. 137-145
    • Wheelock, C.E.1    Goto, S.2    Hammock, B.D.3    Newman, J.W.4
  • 64
    • 0032577202 scopus 로고    scopus 로고
    • cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family
    • Wu X., Prasad P.D., Leibach F.H., and Ganapathy V. cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family. Biochem Biophys Res Commun 246 (1998) 589-595
    • (1998) Biochem Biophys Res Commun , vol.246 , pp. 589-595
    • Wu, X.1    Prasad, P.D.2    Leibach, F.H.3    Ganapathy, V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.