CSF levels of carnitine in children with meningitis, neurologic disorders, acute gastroenteritis, and seizure

Neurology

Volumn 50, Issue 6, 1998, Pages 1869-1871

  Shinawi, Marwan ^a   Gruener, Nachman ^a   Lerner, Aaron ^a,b  

^a CARMEL MEDICAL CENTER   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CARNITINE;

ACUTE GASTROENTERITIS; ADOLESCENT; ARTICLE; ASEPTIC MENINGITIS; BACTERIAL MENINGITIS; BLOOD BRAIN BARRIER; CEREBROSPINAL FLUID ANALYSIS; CHILD; CONTROLLED STUDY; DEHYDRATION; FEMALE; FEVER; HUMAN; MAJOR CLINICAL STUDY; MALE; METABOLIC ACIDOSIS; PRIORITY JOURNAL; SEIZURE;

EID: 0031777332     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.50.6.1869     Document Type: Article

References (9)

1. Rebouche CJ, Engel AG. Tissue distribution of carnitine biosynthetic enzymes in man. Biochim Biophys Acta 1980;630: 22-29.
2. Rosenthal RE, Williams R, Bogaert YE, Getson PR, Fiskum G. Prevention of postischemic canine neurological injury through potentiation of brain energy metabolism by acetyl-L-carnitine. Stroke 1992;23:1312-1318.
3. Osano M, Bell K, Cote L, et al. Double-blind parallel design pilot study of acetyl levocarnitine in patients with Alzheimer's disease. Arch Neurol 1992;49:1137-1141.
4. McGarry JD, Foster DW. Improved and simplified radioisotopic assay for the determination of free and esterified carnitine. J Lipid Res 1976;17:277-281.
5. Huth PJ, Schmidt MJ, Hall PV, Fariello RG, Shug AL. The uptake of carnitine by slices of cerebral cortex. J Neurochem 1981;36:715-723.
6. Fariello RG, Shug AL. Normal values and possible significance of carnitine and its derivatives in human CSF. Neurology 1983;33(suppl 2):69. Abstract.
7. Maccari F, Arseni A, Chodi P, Rammacci T, Angelucci L. Levels of carnitines in brain and other tissues of rats of different ages. Effect of acetyl-L-carnitine administration. Exp Gerontol 1990;25:127-134.
8. Oldendorf WH, Stoller BE, Tishler TA, Williams JL, Oldendorf SZ. Transient blood-brain barrier passage of polar compounds at low pH. Am J Physiol 1994;267:H2229-H2236.
9. Schmidt-Sommerfeld E, Werner D, Penn D. Carnitine plasma concentration in 353 metabolically healthy children. Eur J Pediatr 1988;147:356-360.