Structure-function analysis of the highly conserved charged residues of the membrane protein FT1, the main folic acid transporter of the protozoan parasite Leishmania

Biochemical Pharmacology

Volumn 79, Issue 1, 2010, Pages 30-38

  Dridi, Larbi ^a   Haimeur, Anass ^a   Ouellette, Marc ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Folate transporters; Leishmania; Methotrexate; Site directed mutagenesis; Transport studies

Indexed keywords

AMINO ACID; FOLATE CARRIER; FOLIC ACID; GLYCINE; MEMBRANE PROTEIN; METHIONINE; METHOTREXATE; SERINE; THYMIDINE; UNCLASSIFIED DRUG;

AMINO ACID SYNTHESIS; ARTICLE; CONTROLLED STUDY; GENETIC CONSERVATION; LEISHMANIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; SENSITIZATION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; ANION TRANSPORT PROTEINS; ASPARTIC ACID; CONSERVED SEQUENCE; FOLIC ACID; GLUTAMIC ACID; LEISHMANIA; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN TRANSPORT; PROTOZOAN PROTEINS;

EID: 70350339286     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.07.019     Document Type: Article

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