SCOPUS 정보 검색 플랫폼

Volumn 6, Issue 11, 2009, Pages 2115-2137

Structural alerts, reactive metabolites, and protein covalent binding: How reliable are these attributes as predictors of drug toxicity?

(2) Kalgutkar, Amit S a Didiuk, Mary T a

a PFIZER INC (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (5 CHLORO 2 METHOXYPHENYL) 3 FLUORO 2,3 DIHYDRO 6 TRIFLUOROMETHYL 1H INDOL 2 ONE; 7,8 DIHYDROMETHYSTICIN; ACETYLCYSTEINE; ATORVASTATIN; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE DERIVATIVE; BUSPIRONE; CLOZAPINE; DESFLURANE; ENTACAPONE; HALOTHANE; HERBACEOUS AGENT; ISOFLURANE; KAVA EXTRACT; METHYSTICIN; MIBEFRADIL; NEFAZODONE; OLANZAPINE; PARACETAMOL; PAROXETINE; PIOGLITAZONE; PRAZOSIN; QUETIAPINE; RALOXIFENE; SIMVASTATIN; TADALAFIL; TOLCAPONE; TROGLITAZONE; UNCLASSIFIED DRUG; UNINDEXED DRUG; XENOBIOTIC AGENT;

ADVERSE DRUG REACTION; ALCOHOL ABUSE; ANAPHYLAXIS; ANXIETY DISORDER; APLASTIC ANEMIA; BIOLOGICAL ACTIVITY; BLOOD DYSCRASIA; CARCINOGENICITY; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CONFERENCE PAPER; COVALENT BOND; DEPRESSION; DETOXIFICATION; DNA ADDUCT; DOSE RESPONSE; DRUG CONJUGATION; DRUG ELIMINATION; DRUG ERUPTION; DRUG FATALITY; DRUG INTOXICATION; DRUG METABOLISM; DRUG OVERDOSE; DRUG PROTEIN BINDING; DRUG SAFETY; DRUG SENSITIVITY; DRUG STRUCTURE; DRUG TRANSFORMATION; ELECTROCHEMICAL ANALYSIS; GENETIC POLYMORPHISM; GENOTOXICITY; HUMAN; HYPERTENSION; INSOMNIA; LIVER NECROSIS; LIVER TOXICITY; MUTAGENICITY; MYOPATHY; NONHUMAN; PATHOGENESIS; PIPER METHYSTICUM; PREDICTOR VARIABLE; RECOMMENDED DRUG DOSE; RELIABILITY; RHABDOMYOLYSIS; SKIN MANIFESTATION; T LYMPHOCYTE ACTIVATION;

ANIMALS; BIOTRANSFORMATION; DRUG DISCOVERY; FORECASTING; HUMANS; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; REPRODUCIBILITY OF RESULTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 70350273017 PISSN: 16121872 EISSN: 16121880 Source Type: Journal
DOI: 10.1002/cbdv.200900055 Document Type: Conference Paper

Times cited : (92)

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