Biotransformation of halothane, enflurane, isoflurane, and desflurane to trifluoroacetylated liver proteins: Association between protein acylation and hepatic injury

Anesthesia and Analgesia

Volumn 84, Issue 1, 1997, Pages 173-178

  Njoku, Dolores ^a   Laster, Michael J ^b   Gong, Diane H ^b   Eger II, Edmond I ^b   Reed, George F ^c   Martin, Jackie L ^a,d  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENFLURANE; HALOTHANE; ISOFLURANE;

ACYLATION; ANIMAL EXPERIMENT; ARTICLE; DRUG DEGRADATION; DRUG PROTEIN BINDING; DRUG TRANSFORMATION; ENZYME LINKED IMMUNOSORBENT ASSAY; LIVER MICROSOME METABOLISM; LIVER TOXICITY; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT;

ACYLATION; ANESTHETICS, INHALATION; ANIMALS; ANTIGEN-ANTIBODY REACTIONS; BIOTRANSFORMATION; ENFLURANE; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; HALOTHANE; HEPATITIS, TOXIC; HUMANS; IMMUNOHISTOCHEMISTRY; ISOFLURANE; LIVER; MALE; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0031027091     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199701000-00031     Document Type: Article

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