Multiplexing a high-throughput liability assay to leverage efficiencies

Assay and Drug Development Technologies

Volumn 7, Issue 3, 2009, Pages 294-303

  Herbst, John ^a   Anthony, Monique ^a   Stewart, Jeremy ^a   Connors, David ^a   Chen, Taosheng ^b   Banks, Martyn ^a   Petrillo, Edward W ^c   Agler, Michele ^a  

^a BRISTOL MYERS SQUIBB   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c Discovery Performance Strategies LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A4; PREGNANE X RECEPTOR;

ARTICLE; CELL ACTIVATION; CELL DENSITY; CELL VIABILITY; CONTROLLED STUDY; CRYOPRESERVATION; CYTOTOXICITY; DOSE RESPONSE; DOWN REGULATION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; PROTEIN EXPRESSION;

CELL LINE, TUMOR; CRYOPRESERVATION; CYTOCHROME P-450 CYP3A; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; EFFICIENCY; ENZYME INDUCTION; HUMANS; LUCIFERASES; RECEPTORS, STEROID; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 70350165316     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/adt.2008.184     Document Type: Article

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