Mechanism of abnormal growth in astrocytes derived from a mouse model of GM2 gangliosidosis

Journal of Neurochemistry

Volumn 111, Issue 4, 2009, Pages 1031-1041

  Kawashima, Nagako ^a,b   Tsuji, Daisuke ^a,c   Okuda, Tetsuya ^a   Itoh, Kohji ^a,c   Nakayama, Ken Ichi ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Astrocyte; Cell proliferation; ERK; GM2 ganglioside; Sandhoff disease; Signal transduction

Indexed keywords

BETA N ACETYLHEXOSAMINIDASE A; BETA N ACETYLHEXOSAMINIDASE B; GANGLIOSIDE GM3; GLYCOLIPID; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; RECOMBINANT ENZYME;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; ASTROCYTE; BETA CHAIN; CELL PROLIFERATION; CELL SURFACE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE; GENE MUTATION; GLIOSIS; GM2 GANGLIOSIDOSIS; GROWTH RATE; HEXB GENE; LYSOSOME; MOUSE; NERVE CELL GROWTH; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; SANDHOFF DISEASE; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CELL PROLIFERATION; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISEASE MODELS, ANIMAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLOW CYTOMETRY; GANGLIOSIDES; GANGLIOSIDOSES, GM2; GLIAL FIBRILLARY ACIDIC PROTEIN; HEXOSAMINIDASE A; HEXOSAMINIDASE B; LECTINS; LYSOSOMES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; O ANTIGENS; SANDHOFF DISEASE; SIGNAL TRANSDUCTION; SPINAL CORD;

MUS;

EID: 70350133703     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06391.x     Document Type: Article

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