Mice lacking both subunits of lysosomal β-hexosaminidase display gangliosidosis and mucopolysaccharidosis

Nature Genetics

Volumn 14, Issue 3, 1996, Pages 348-352

  Sango, Kazunori ^a   McDonald, Michael P ^b   Crawley, Jacqueline N ^b   Mack, Michelle L ^a   Tifft, Cynthia J ^a,c   Skop, Elisa ^d   Starr, Christopher M ^d   Hoffmann, Alexander ^e   Sandhoff, Konrad ^e   Suzuki, Kinuko ^f   Proia, Richard L ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^c CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^d Glyko Inc   (United States)

^e UNIVERSITY OF BONN   (Germany)

^f UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA N ACETYLHEXOSAMINIDASE; GANGLIOSIDE; GLYCOSAMINOGLYCAN; ISOENZYME; SPHINGOLIPID;

ANIMAL; ANIMAL BEHAVIOR; ARTICLE; BRAIN; CHEMISTRY; DISEASE MODEL; ENZYMOLOGY; FEMALE; FIBROBLAST; GANGLIOSIDOSIS; GENETICS; HUMAN; LIVER; LYSOSOME; MALE; METABOLISM; MOUSE; MOUSE MUTANT; MUCOPOLYSACCHARIDOSIS; PATHOLOGY; SPLEEN; THIN LAYER CHROMATOGRAPHY; URINE;

ANIMALS; BEHAVIOR, ANIMAL; BETA-N-ACETYLHEXOSAMINIDASE; BRAIN; CHROMATOGRAPHY, THIN LAYER; DISEASE MODELS, ANIMAL; FEMALE; FIBROBLASTS; GANGLIOSIDES; GANGLIOSIDOSES; GLYCOSAMINOGLYCANS; HUMANS; ISOENZYMES; LIVER; LYSOSOMES; MALE; MICE; MICE, KNOCKOUT; MUCOPOLYSACCHARIDOSES; SPHINGOLIPIDS; SPLEEN;

EID: 16144368388     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng1196-348     Document Type: Letter

References (12)

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