Tyrosine kinase activity of epidermal growth factor receptor is regulated by GM3 binding through carbohydrate to carbohydrate interactions

Journal of Biological Chemistry

Volumn 284, Issue 10, 2009, Pages 6147-6155

  Kawashima, Nagako ^a,b   Yoon, Seon Joo ^b,d   Itoh, Kohji ^c   Nakayama, Ken Ichi ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

^d OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTORS; GALACTOSIDASE; GLYCOSIDASE; GLYCOSYLATED; IN-SITU; IN-VITRO; INHIBITORY EFFECT; KINASE DOMAINS; LIGAND BINDING; MANNOSIDASE; N-GLYCAN; N-GLYCANS; NEURAMINIDASE; TRANS-MEMBRANE PROTEINS; TYROSINE KINASE;

AMINO ACIDS; BIOACTIVITY; CARBOHYDRATES; COCHANNEL INTERFERENCE; PEPTIDES; PHOSPHORYLATION;

CELL MEMBRANES;

ALPHA MANNOSIDASE; ALPHA MANNOSIDASE 1B; ANTISENSE OLIGONUCLEOTIDE; BETA GALACTOSIDASE; EPIDERMAL GROWTH FACTOR RECEPTOR; GANGLIOSIDE GM3; GLYCAN DERIVATIVE; GLYCOSIDASE; MANNOSE; N ACETYLGLUCOSAMINE; PROTEIN TYROSINE KINASE; SIALIDASE; UNCLASSIFIED DRUG; EGFR PROTEIN, HUMAN;

ARTICLE; CARBOHYDRATE ANALYSIS; CARBOHYDRATE CARBOHYDRATE INTERACTION; CARBOHYDRATE SYNTHESIS; CHEMICAL INTERACTION; CONTROLLED STUDY; ENZYMATIC DEGRADATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; RECEPTOR BINDING; DRUG EFFECT; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE;

ACETYLGLUCOSAMINE; CELL LINE, TUMOR; G(M3) GANGLIOSIDE; HUMANS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 65249091494     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M808171200     Document Type: Article

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