Nitrooxymethyl-substituted analogues of celecoxib: Synthesis and pharmacological characterization

Chemistry and Biodiversity

Volumn 6, Issue 3, 2009, Pages 369-379

  Boschi, Donatella ^a   Lazzarato, Loretta ^a   Rolando, Barbara ^a   Filieri, Andrea ^a   Cena, Clara ^a   Di Stilo, Antonella ^a   Fruttero, Roberta ^a   Gasco, Alberto ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4 (HYDROXYMETHYL)ACETOPHENONE; 4 (METHYLCARBONYL)PHENYLHYDRAZINE; 4 [1 [4 (AMINOSULFONYL)PHENYL] 3 (TRIFLUOROMETHYL) 1H PYRAZOL 5 YL]BENZYL NITRATE; 4 [1 [4 (HYDROXYMETHYL)PHENYL] 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]PHENYLMETHANOL; 4 [5 ( METHYLPHENYL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]PHENYLMETHANOL; 4 [5 [ (HYDROXYMETHYL)PHENYL] 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZENESULFONAMIDE; 4 SULFAMOYLPHENYLHYDRAZINE; 4,4,4 TRIFLUORO 1 [4 (HYDROXYMETHYL)PHENYL]BUTANE 1,3 DIONE; CELECOXIB DERIVATIVE; CYCLOOXYGENASE 2 INHIBITOR; METHYL 4 [5 (4 METHYLPHENYL) 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZOATE; METHYL 4 [5 [4 (HYDROXYMETHYL)PHENYL] 3 (TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]BENZOATE; PROSTAGLANDIN SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; DRUG POTENCY; DRUG SELECTIVITY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TRANSFORMATION; HUMAN; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; VASODILATATION;

ANIMALS; CYCLOOXYGENASE INHIBITORS; DRUG STABILITY; HUMANS; MALE; NITROGEN OXIDES; PLATELET AGGREGATION INHIBITORS; PYRAZOLES; RATS; SULFONAMIDES; VASODILATOR AGENTS;

RATTUS;

EID: 64549150228     PISSN: 16121872     EISSN: 16121880     Source Type: Journal    
DOI: 10.1002/cbdv.200800307     Document Type: Article

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