메뉴 건너뛰기




Volumn 115, Issue 20, 2009, Pages 4795-4806

Genetically transforming human mesenchymal stem cells to sarcomas: Changes in cellular phenotype and multilineage differentiation potential

Author keywords

Human mesenchymal stem cell; Multilineage differentiation potential; Osteosarcoma; Tumorigenesis

Indexed keywords

TELOMERASE REVERSE TRANSCRIPTASE; VIRUS T ANTIGEN;

EID: 70350088421     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.24519     Document Type: Article
Times cited : (60)

References (31)
  • 2
    • 33846882630 scopus 로고    scopus 로고
    • Molecular pathogenesis of osteosarcoma
    • Kansara M, Thomas DM. Molecular pathogenesis of osteosarcoma. DNA Cell Biol. 2007;26:1-18.
    • (2007) DNA Cell Biol , vol.26 , pp. 1-18
    • Kansara, M.1    Thomas, D.M.2
  • 3
    • 33845965676 scopus 로고    scopus 로고
    • Soft tissue osteosarcoma: A case report
    • Hulse N, Paul AS. Soft tissue osteosarcoma: a case report. Acta Orthop Belg. 2006;72:783-785. (Pubitemid 46048250)
    • (2006) Acta Orthopaedica Belgica , vol.72 , Issue.6 , pp. 783-785
    • Hulse, N.1    Paul, A.S.2
  • 5
    • 28144434353 scopus 로고    scopus 로고
    • Mesenchymal stem cells
    • Vaananen HK. Mesenchymal stem cells. Ann Med. 2005; 37:469-479.
    • (2005) Ann Med , vol.37 , pp. 469-479
    • Vaananen, H.K.1
  • 12
    • 0033614998 scopus 로고    scopus 로고
    • Creation of human tumour cells with defined genetic elements
    • Hahn WC, Counter CM, Lundberg AS, et al. Creation of human tumour cells with defined genetic elements. Nature. 1999;400:464-468.
    • (1999) Nature , vol.400 , pp. 464-468
    • Hahn, W.C.1    Counter, C.M.2    Lundberg, A.S.3
  • 14
    • 0035392982 scopus 로고    scopus 로고
    • Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma
    • Sonoda Y, Ozawa T, Hirose Y, et al. Formation of intracranial tumors by genetically modified human astrocytes defines 4 pathways critical in the development of human anaplastic astrocytoma. Cancer Res. 2001;61:4956-4960. (Pubitemid 32681517)
    • (2001) Cancer Research , vol.61 , Issue.13 , pp. 4956-4960
    • Sonoda, Y.1    Ozawa, T.2    Hirose, Y.3    Aldape, K.D.4    McMahon, M.5    Berger, M.S.6    Pieper, R.O.7
  • 16
    • 19644366513 scopus 로고    scopus 로고
    • Genetic modeling of human rhabdomyosarcoma
    • Linardic CM, Downie DL, Qualman S, et al. Genetic modeling of human rhabdomyosarcoma. Cancer Res. 2005; 65:4490-5445
    • (2005) Cancer Res , vol.65 , pp. 4490-5445
    • Linardic, C.M.1    Downie, D.L.2    Qualman, S.3
  • 18
    • 16544374778 scopus 로고    scopus 로고
    • Analysis of telomerase activity and telomere length in bone and soft tissue tumors
    • Terasaki T, Kyo S, Takakura M, et al. Analysis of telomerase activity and telomere length in bone and soft tissue tumors. Oncol Rep. 2004;11:1307-1311.
    • (2004) Oncol Rep , vol.11 , pp. 1307-1311
    • Terasaki, T.1    Kyo, S.2    Takakura, M.3
  • 20
    • 0032511896 scopus 로고    scopus 로고
    • Integration of SV40 in human osteosarcoma DNA
    • Mendoza SM, Konishi T, Miller CW. Integration of SV40 in human osteosarcoma DNA. Oncogene. 1998;17:2457-2462. (Pubitemid 28544715)
    • (1998) Oncogene , vol.17 , Issue.19 , pp. 2457-2462
    • Mendoza, S.M.1    Konishi, T.2    Miller, C.W.3
  • 22
    • 0026495364 scopus 로고
    • Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors
    • Kallioniemi A, Kallioniemi OP, Sudar D, et al. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science. 1992;258:818-821.
    • (1992) Science , vol.258 , pp. 818-821
    • Kallioniemi, A.1    Kallioniemi, O.P.2    Sudar, D.3
  • 23
    • 34547131814 scopus 로고    scopus 로고
    • Over-expression of parathyroid hormone Type 1 receptor confers an aggressive phenotype in osteosarcoma
    • Yang R, Hoang BH, Kubo T, et al. Over-expression of parathyroid hormone Type 1 receptor confers an aggressive phenotype in osteosarcoma. Int J Cancer. 2007;121:943-954.
    • (2007) Int J Cancer , vol.121 , pp. 943-954
    • Yang, R.1    Hoang, B.H.2    Kubo, T.3
  • 24
    • 33845664988 scopus 로고    scopus 로고
    • In vitro transformation of mesenchymal stem cells by oncogenic HrasVal12
    • Shima Y, Okamoto T, Aoyama T, et al. In vitro transformation of mesenchymal stem cells by oncogenic HrasVal12. Biochem Biophys Res Commun. 2007;353:60-66.
    • (2007) Biochem Biophys Res Commun , vol.353 , pp. 60-66
    • Shima, Y.1    Okamoto, T.2    Aoyama, T.3
  • 25
    • 34547566701 scopus 로고    scopus 로고
    • Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes
    • Ince TA, Richardson AL, Bell GW, et al. Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes. Cancer Cell. 2007;12:160-170.
    • (2007) Cancer Cell , vol.12 , pp. 160-170
    • Ince, T.A.1    Richardson, A.L.2    Bell, G.W.3
  • 26
    • 0037900074 scopus 로고    scopus 로고
    • Arf-p53 tumor suppressor pathway regulates cell motility by suppression of phosphoinositide 3-kinase and Rac1 GTPase activities
    • DOI 10.1074/jbc.M300341200
    • Guo F, Gao Y, Wang L, et al. p19Arf-p53 tumor suppressor pathway regulates cell motility by suppression of phosphoinositide 3-kinase and Rac1 GTPase activities. J Biol Chem. 2003;278:14414-14419. (Pubitemid 36799994)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.16 , pp. 14414-14419
    • Guo, F.1    Gao, Y.2    Wang, L.3    Zheng, Y.4
  • 27
    • 0141482096 scopus 로고    scopus 로고
    • p38 kinase is a key signaling molecule for H-Ras-induced cell motility and invasive phenotype in human breast epithelial cells
    • Kim MS, Lee EJ, Kim HR, et al. p38 kinase is a key signaling molecule for H-Ras-induced cell motility and invasive phenotype in human breast epithelial cells. Cancer Res. 2003;63:5454-5461.
    • (2003) Cancer Res , vol.63 , pp. 5454-5461
    • Kim, M.S.1    Lee, E.J.2    Kim, H.R.3
  • 28
    • 33847627873 scopus 로고    scopus 로고
    • Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility
    • DOI 10.1038/nsmb1208, PII NSMB1208
    • Xia M, Land H. Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility. Nat Struct Mol Biol. 2007;14:215-223. (Pubitemid 46355577)
    • (2007) Nature Structural and Molecular Biology , vol.14 , Issue.3 , pp. 215-223
    • Xia, M.1    Land, H.2
  • 29
    • 50149110590 scopus 로고    scopus 로고
    • Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage
    • Berman SD, Calo E, Landman AS, et al. Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage. Proc Natl Acad Sci U S A. 2008;105: 11851-11856.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 11851-11856
    • Berman, S.D.1    Calo, E.2    Landman, A.S.3
  • 30
    • 33846458609 scopus 로고    scopus 로고
    • Human xenograft osteosarcoma models with spontaneous metastasis in mice: Clinical relevance and applicability for drug testing
    • Dass CR, Ek ET, Choong PF. Human xenograft osteosarcoma models with spontaneous metastasis in mice: clinical relevance and applicability for drug testing. J Cancer Res. Clin Oncol. 2007;133:193-198.
    • (2007) J Cancer Res. Clin Oncol , vol.133 , pp. 193-198
    • Dass, C.R.1    Ek, E.T.2    Choong, P.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.