-
1
-
-
0020520516
-
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
-
Land, H., Parada, L.F. & Weinberg, R.A. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 304, 596-602 (1983).
-
(1983)
Nature
, vol.304
, pp. 596-602
-
-
Land, H.1
Parada, L.F.2
Weinberg, R.A.3
-
2
-
-
0020520517
-
Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture
-
Ruley, H.E. Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture. Nature 304, 602-606 (1983).
-
(1983)
Nature
, vol.304
, pp. 602-606
-
-
Ruley, H.E.1
-
3
-
-
0033614998
-
Creation of human tumour cells with defined genetic elements
-
Hahn, W.C. et al. Creation of human tumour cells with defined genetic elements. Nature 400, 464-468 (1999).
-
(1999)
Nature
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
-
4
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D. & Weinberg, R.A. The hallmarks of cancer. Cell 100, 57-70 (2000).
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
5
-
-
0024026804
-
Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation
-
Ridley, A.J., Paterson, H.F., Noble, M. & Land, H. Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation. EMBO J. 7, 1635-1645 (1988).
-
(1988)
EMBO J
, vol.7
, pp. 1635-1645
-
-
Ridley, A.J.1
Paterson, H.F.2
Noble, M.3
Land, H.4
-
6
-
-
0040433650
-
Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene
-
Hirakawa, T. & Ruley, H.E. Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene. Proc. Natl. Acad. Sci. USA 85, 1519-1523 (1988).
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 1519-1523
-
-
Hirakawa, T.1
Ruley, H.E.2
-
7
-
-
0030950537
-
Cooperating oncogenes converge to regulate cyclin/cdk complexes
-
Lloyd, A.C. et al. Cooperating oncogenes converge to regulate cyclin/cdk complexes. Genes Dev. 11, 663-677 (1997).
-
(1997)
Genes Dev
, vol.11
, pp. 663-677
-
-
Lloyd, A.C.1
-
8
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(ink4a)
-
Serrano, M., Lin, A.W., McCurrach, M.E., Beach, D. & Lowe, S.W. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(ink4a). Cell 88, 593-602 (1997).
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
9
-
-
0030871667
-
High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1
-
Sewing, A., Wiseman, B., Lloyd, A.C. & Land, H. High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1. Mol. Cell. Biol. 17, 5588-5597 (1997).
-
(1997)
Mol. Cell. Biol
, vol.17
, pp. 5588-5597
-
-
Sewing, A.1
Wiseman, B.2
Lloyd, A.C.3
Land, H.4
-
10
-
-
0030835430
-
Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1
-
Woods, D. et al. Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1. Mol. Cell. Biol. 17, 5598-5611 (1997).
-
(1997)
Mol. Cell. Biol
, vol.17
, pp. 5598-5611
-
-
Woods, D.1
-
11
-
-
0033214995
-
Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1)
-
Perez-Roger, I., Kim, S.H., Griffiths, B., Sewing, A. & Land, H. Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1). EMBO J. 18, 5310-5320 (1999).
-
(1999)
EMBO J
, vol.18
, pp. 5310-5320
-
-
Perez-Roger, I.1
Kim, S.H.2
Griffiths, B.3
Sewing, A.4
Land, H.5
-
12
-
-
0032192153
-
Senescence of human fibroblasts induced by oncogenic Raf
-
Zhu, J., Woods, D., McMahon, M. & Bishop, J.M. Senescence of human fibroblasts induced by oncogenic Raf. Genes Dev. 12, 2997-3007 (1998).
-
(1998)
Genes Dev
, vol.12
, pp. 2997-3007
-
-
Zhu, J.1
Woods, D.2
McMahon, M.3
Bishop, J.M.4
-
13
-
-
0032504784
-
p19ARF links the tumour suppressor p53 to Ras
-
Palmero, I., Pantoja, C. & Serrano, M. p19ARF links the tumour suppressor p53 to Ras. Nature 395, 125-126 (1998).
-
(1998)
Nature
, vol.395
, pp. 125-126
-
-
Palmero, I.1
Pantoja, C.2
Serrano, M.3
-
14
-
-
0030728468
-
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
-
Kamijo, T. et al. Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell 91, 649-659 (1997).
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
-
15
-
-
1242340431
-
Oncogenic Ras and its role in tumor cell invasion and metastasis
-
Campbell, P.M. & Der, C.J. Oncogenic Ras and its role in tumor cell invasion and metastasis. Semin. Cancer Biol. 14, 105-114 (2004).
-
(2004)
Semin. Cancer Biol
, vol.14
, pp. 105-114
-
-
Campbell, P.M.1
Der, C.J.2
-
16
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon, E.R. & Vogelstein, B. A genetic model for colorectal tumorigenesis. Cell 61, 759-767 (1990).
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
17
-
-
0033887693
-
Progression model for pancreatic cancer
-
Hruban, R.H., Goggins, M., Parsons, J. & Kern, S.E. Progression model for pancreatic cancer. Clin. Cancer Res. 6, 2969-2972 (2000).
-
(2000)
Clin. Cancer Res
, vol.6
, pp. 2969-2972
-
-
Hruban, R.H.1
Goggins, M.2
Parsons, J.3
Kern, S.E.4
-
18
-
-
0034910622
-
Molecular genetics of small cell lung carcinoma
-
Wistuba, I.I., Gazdar, A.F. & Minna, J.D. Molecular genetics of small cell lung carcinoma. Semin. Oncol. 28, 3-13 (2001).
-
(2001)
Semin. Oncol
, vol.28
, pp. 3-13
-
-
Wistuba, I.I.1
Gazdar, A.F.2
Minna, J.D.3
-
19
-
-
28544432790
-
The differential effects of mutant p53 alleles on advanced murine lung cancer
-
Jackson, E.L. et al. The differential effects of mutant p53 alleles on advanced murine lung cancer. Cancer Res. 65, 10280-10288 (2005).
-
(2005)
Cancer Res
, vol.65
, pp. 10280-10288
-
-
Jackson, E.L.1
-
20
-
-
13444278808
-
The absence of p53 promotes metastasis in a novel somatic mouse model for hepatocellular carcinoma
-
Lewis, B.C. et al. The absence of p53 promotes metastasis in a novel somatic mouse model for hepatocellular carcinoma. Mol. Cell. Biol. 25, 1228-1237 (2005).
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 1228-1237
-
-
Lewis, B.C.1
-
21
-
-
0842281652
-
Rho and Rac take center stage
-
Burridge, K. & Wennerberg, K. Rho and Rac take center stage. Cell 116, 167-179 (2004).
-
(2004)
Cell
, vol.116
, pp. 167-179
-
-
Burridge, K.1
Wennerberg, K.2
-
22
-
-
0344305784
-
Cell migration: Integrating signals from front to back
-
Ridley, A.J. et al. Cell migration: integrating signals from front to back. Science 302, 1704-1709 (2003).
-
(2003)
Science
, vol.302
, pp. 1704-1709
-
-
Ridley, A.J.1
-
24
-
-
0026654125
-
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
-
Ridley, A.J., Paterson, H.F., Johnston, C.L., Diekmann, D. & Hall, A. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70, 401-410 (1992).
-
(1992)
Cell
, vol.70
, pp. 401-410
-
-
Ridley, A.J.1
Paterson, H.F.2
Johnston, C.L.3
Diekmann, D.4
Hall, A.5
-
25
-
-
0028961293
-
Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
-
Nobes, C.D. & Hall, A. Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81, 53-62 (1995).
-
(1995)
Cell
, vol.81
, pp. 53-62
-
-
Nobes, C.D.1
Hall, A.2
-
26
-
-
0035833247
-
RhoA is required for monocyte tail retraction during transendothelial migration
-
Worthylake, R.A., Lemoine, S., Watson, J.M. & Burridge, K. RhoA is required for monocyte tail retraction during transendothelial migration. J. Cell Biol. 154, 147-160 (2001).
-
(2001)
J. Cell Biol
, vol.154
, pp. 147-160
-
-
Worthylake, R.A.1
Lemoine, S.2
Watson, J.M.3
Burridge, K.4
-
27
-
-
0026778133
-
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
-
Ridley, A.J. & Hall, A. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70, 389-399 (1992).
-
(1992)
Cell
, vol.70
, pp. 389-399
-
-
Ridley, A.J.1
Hall, A.2
-
28
-
-
0033615966
-
Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behavior
-
Sander, E.E., ten Klooster, J.P., van Delft, S., van der Kammen, R.A. & Collard, J.G. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J. Cell Biol. 147, 1009-1022 (1999).
-
(1999)
J. Cell Biol
, vol.147
, pp. 1009-1022
-
-
Sander, E.E.1
ten Klooster, J.P.2
van Delft, S.3
van der Kammen, R.A.4
Collard, J.G.5
-
29
-
-
0037341905
-
Redox-dependent downregulation of Rho by Rac
-
Nimnual, A.S., Taylor, L.J. & Bar-Sagi, D. Redox-dependent downregulation of Rho by Rac. Nat. Cell Biol. 5, 236-241 (2003).
-
(2003)
Nat. Cell Biol
, vol.5
, pp. 236-241
-
-
Nimnual, A.S.1
Taylor, L.J.2
Bar-Sagi, D.3
-
30
-
-
33751256003
-
p120-Catenin and p190 RhoGAP regulate cell-Cell adhesion by coordinating antagonism between Rac and Rho
-
Wildenberg, G.A. et al. p120-Catenin and p190 RhoGAP regulate cell-Cell adhesion by coordinating antagonism between Rac and Rho. Cell 127, 1027-1039 (2006).
-
(2006)
Cell
, vol.127
, pp. 1027-1039
-
-
Wildenberg, G.A.1
-
31
-
-
0034658674
-
Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition
-
Zondag, G.C. et al. Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition. J. Cell Biol. 149, 775-782 (2000).
-
(2000)
J. Cell Biol
, vol.149
, pp. 775-782
-
-
Zondag, G.C.1
-
32
-
-
0035865137
-
Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility
-
Sahai, E., Olson, M.F. & Marshall, C.J. Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility. EMBO J. 20, 755-766 (2001).
-
(2001)
EMBO J
, vol.20
, pp. 755-766
-
-
Sahai, E.1
Olson, M.F.2
Marshall, C.J.3
-
33
-
-
0027952703
-
Involvement of Rho p21 small GTP-binding protein and its regulator in the HGF-induced cell motility
-
Takaishi, K. et al. Involvement of Rho p21 small GTP-binding protein and its regulator in the HGF-induced cell motility. Oncogene 9, 273-279 (1994).
-
(1994)
Oncogene
, vol.9
, pp. 273-279
-
-
Takaishi, K.1
-
34
-
-
0032570796
-
Small GTP-binding protein Rho stimulates the actomyosin system, leading to invasion of tumor cells
-
Yoshioka, K., Matsumura, F., Akedo, H. & Itoh, K. Small GTP-binding protein Rho stimulates the actomyosin system, leading to invasion of tumor cells. J. Biol. Chem. 273, 5146-5154 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 5146-5154
-
-
Yoshioka, K.1
Matsumura, F.2
Akedo, H.3
Itoh, K.4
-
35
-
-
0042349229
-
ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility
-
Vial, E., Sahai, E. & Marshall, C.J. ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility. Cancer Cell 4, 67-79 (2003).
-
(2003)
Cancer Cell
, vol.4
, pp. 67-79
-
-
Vial, E.1
Sahai, E.2
Marshall, C.J.3
-
36
-
-
1642580743
-
Involvement of Rho family GTPases in p19Arf- and p53-mediated proliferation of primary mouse embryonic fibroblasts
-
Guo, F. & Zheng, Y. Involvement of Rho family GTPases in p19Arf- and p53-mediated proliferation of primary mouse embryonic fibroblasts. Mol. Cell. Biol. 24, 1426-1438 (2004).
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 1426-1438
-
-
Guo, F.1
Zheng, Y.2
-
37
-
-
0037093470
-
Regulation of Cdc42-mediated morphological effects: A novel function for p53
-
Gadea, G., Lapasset, L., Gauthier-Rouviere, C. & Roux, P. Regulation of Cdc42-mediated morphological effects: a novel function for p53. EMBO J. 21, 2373-2382 (2002).
-
(2002)
EMBO J
, vol.21
, pp. 2373-2382
-
-
Gadea, G.1
Lapasset, L.2
Gauthier-Rouviere, C.3
Roux, P.4
-
38
-
-
0029670841
-
Synergy between Apc min and an activated ras mutation is sufficient to induce colon carcinomas
-
D'Abaco, G.M., Whitehead, R.H. & Burgess, A.W. Synergy between Apc min and an activated ras mutation is sufficient to induce colon carcinomas. Mol. Cell. Biol. 16, 884-891 (1996).
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 884-891
-
-
D'Abaco, G.M.1
Whitehead, R.H.2
Burgess, A.W.3
-
39
-
-
0027498506
-
Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice
-
Whitehead, R.H., VanEeden, P.E., Noble, M.D., Ataliotis, P. & Jat, P.S. Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice. Proc. Natl. Acad. Sci. USA 90, 587-591 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 587-591
-
-
Whitehead, R.H.1
VanEeden, P.E.2
Noble, M.D.3
Ataliotis, P.4
Jat, P.S.5
-
40
-
-
0023187867
-
A rapid in vitro assay for quantitating the invasive potential of tumor cells
-
Albini, A. et al. A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res. 47, 3239-3245 (1987).
-
(1987)
Cancer Res
, vol.47
, pp. 3239-3245
-
-
Albini, A.1
-
41
-
-
0027058972
-
Molecular and cellular analysis of basement membrane invasion by human breast cancer cells in Matrigel-based in vitro assays
-
Bae, S.N. et al. Molecular and cellular analysis of basement membrane invasion by human breast cancer cells in Matrigel-based in vitro assays. Breast Cancer Res. Treat. 24, 241-255 (1993).
-
(1993)
Breast Cancer Res. Treat
, vol.24
, pp. 241-255
-
-
Bae, S.N.1
-
42
-
-
0033081753
-
Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
-
Ren, X.D., Kiosses, W.B. & Schwartz, M.A. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J. 18, 578-585 (1999).
-
(1999)
EMBO J
, vol.18
, pp. 578-585
-
-
Ren, X.D.1
Kiosses, W.B.2
Schwartz, M.A.3
-
43
-
-
0032583205
-
Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase
-
Sander, E.E. et al. Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase. J. Cell Biol. 143, 1385-1398 (1998).
-
(1998)
J. Cell Biol
, vol.143
, pp. 1385-1398
-
-
Sander, E.E.1
-
44
-
-
0035072953
-
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I
-
Coleman, M.L. et al. Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I. Nat. Cell Biol. 3, 339-345 (2001).
-
(2001)
Nat. Cell Biol
, vol.3
, pp. 339-345
-
-
Coleman, M.L.1
-
45
-
-
0003000807
-
Tools of the trade: Use of dominant-inhibitory mutants of Ras-family GTPases
-
Feig, L.A. Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases. Nat. Cell Biol. 1, E25-E27 (1999).
-
(1999)
Nat. Cell Biol
, vol.1
-
-
Feig, L.A.1
-
46
-
-
0035825193
-
Differential localization of Rho GTPases in live cells: Regulation by hypervariable regions and RhoGDI binding
-
Michaelson, D. et al. Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding. J. Cell Biol. 152, 111-126 (2001).
-
(2001)
J. Cell Biol
, vol.152
, pp. 111-126
-
-
Michaelson, D.1
-
47
-
-
0037853126
-
Cadherin engagement inhibits RhoA via p190 RhoGAP
-
Noren, N.K., Arthur, W.T. & Burridge, K. Cadherin engagement inhibits RhoA via p190 RhoGAP. J. Biol. Chem. 278, 13615-13618 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 13615-13618
-
-
Noren, N.K.1
Arthur, W.T.2
Burridge, K.3
-
48
-
-
0035071323
-
p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation
-
Brouns, M.R., Matheson, S.F. & Settleman, J. p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation. Nat. Cell Biol. 3, 361-367 (2001).
-
(2001)
Nat. Cell Biol
, vol.3
, pp. 361-367
-
-
Brouns, M.R.1
Matheson, S.F.2
Settleman, J.3
-
49
-
-
0031724591
-
Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation
-
Roof, R.W. et al. Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation. Mol. Cell. Biol. 18, 7052-7063 (1998).
-
(1998)
Mol. Cell. Biol
, vol.18
, pp. 7052-7063
-
-
Roof, R.W.1
-
50
-
-
0031030898
-
Tandem SH2 binding sites mediate the RasGAP-RhoGAP interaction: A conformational mechanism for SH3 domain regulation
-
Hu, K.Q. & Settleman, J. Tandem SH2 binding sites mediate the RasGAP-RhoGAP interaction: a conformational mechanism for SH3 domain regulation. EMBO J. 16, 473-483 (1997).
-
(1997)
EMBO J
, vol.16
, pp. 473-483
-
-
Hu, K.Q.1
Settleman, J.2
-
51
-
-
10944236962
-
Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome
-
Olive, K.P. et al. Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome. Cell 119, 847-860 (2004).
-
(2004)
Cell
, vol.119
, pp. 847-860
-
-
Olive, K.P.1
-
52
-
-
13644260907
-
Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome
-
Lang, G.A. et al. Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome. Cell 119, 861-872 (2004).
-
(2004)
Cell
, vol.119
, pp. 861-872
-
-
Lang, G.A.1
-
53
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp, T.R., Bernards, R. & Agami, R. A system for stable expression of short interfering RNAs in mammalian cells. Science 296, 550-553 (2002).
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
54
-
-
0028981052
-
Detection of p21ras mutations in colorectal adenomas and carcinomas by enzyme-linked immunosorbent assay
-
Schroy, P.C., III et al. Detection of p21ras mutations in colorectal adenomas and carcinomas by enzyme-linked immunosorbent assay. Cancer 76, 201-209 (1995).
-
(1995)
Cancer
, vol.76
, pp. 201-209
-
-
Schroy III, P.C.1
-
55
-
-
0034745679
-
Methylation silencing and mutations of the p14ARF and p16INK4a genes in colon cancer
-
Burri, N. et al. Methylation silencing and mutations of the p14ARF and p16INK4a genes in colon cancer. Lab. Invest. 81, 217-229 (2001).
-
(2001)
Lab. Invest
, vol.81
, pp. 217-229
-
-
Burri, N.1
-
56
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
Bunz, F. et al. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 282, 1497-1501 (1998).
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
-
57
-
-
1942509343
-
Adhesion-dependent regulation of p190 RhoGAP in the developing brain by the Abl-related gene tyrosine kinase
-
Hernandez, S.E., Settleman, J. & Koleske, A.J. Adhesion-dependent regulation of p190 RhoGAP in the developing brain by the Abl-related gene tyrosine kinase. Curr. Biol. 14, 691-696 (2004).
-
(2004)
Curr. Biol
, vol.14
, pp. 691-696
-
-
Hernandez, S.E.1
Settleman, J.2
Koleske, A.J.3
-
58
-
-
0034681336
-
The low M(r) protein-tyrosine phosphatase is involved in Rho-mediated cytoskeleton rearrangement after integrin and platelet-derived growth factor stimulation
-
Chiarugi, P. et al. The low M(r) protein-tyrosine phosphatase is involved in Rho-mediated cytoskeleton rearrangement after integrin and platelet-derived growth factor stimulation. J. Biol. Chem. 275, 4640-4646 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 4640-4646
-
-
Chiarugi, P.1
-
59
-
-
0037226593
-
A molecular signaure of metastasis in primary solid tumors
-
Ramaswamy, S., Ross, K.N., Lander, E.S. & Golub, T.R. A molecular signaure of metastasis in primary solid tumors. Nat. Genet. 33, 49-54 (2003).
-
(2003)
Nat. Genet
, vol.33
, pp. 49-54
-
-
Ramaswamy, S.1
Ross, K.N.2
Lander, E.S.3
Golub, T.R.4
-
60
-
-
18244409687
-
Gene expression profiling predicts clinical outcome of breast cancer
-
van't Veer, L.J. et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 415, 530-536 (2002).
-
(2002)
Nature
, vol.415
, pp. 530-536
-
-
van't Veer, L.J.1
-
61
-
-
0025352187
-
Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
-
Morgenstern, J.P. & Land, H. Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 18, 3587-3596 (1990).
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 3587-3596
-
-
Morgenstern, J.P.1
Land, H.2
-
62
-
-
0036726313
-
Stable suppression of tumorigenicity by virus-mediated RNA interference
-
Brummelkamp, T.R., Bernards, R. & Agami, R. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2, 243-247 (2002).
-
(2002)
Cancer Cell
, vol.2
, pp. 243-247
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
63
-
-
0033594123
-
Rho GTPases control polarity, protrusion, and adhesion during cell movement
-
Nobes, C.D. & Hall, A. Rho GTPases control polarity, protrusion, and adhesion during cell movement. J. Cell Biol. 144, 1235-1244 (1999).
-
(1999)
J. Cell Biol
, vol.144
, pp. 1235-1244
-
-
Nobes, C.D.1
Hall, A.2
-
64
-
-
12444340440
-
p250GAP, a novel brain-enriched GTPase-activating protein for Rho family GTPases, is involved in the N-methyl-d-aspartate receptor signaling
-
Nakazawa, T. et al. p250GAP, a novel brain-enriched GTPase-activating protein for Rho family GTPases, is involved in the N-methyl-d-aspartate receptor signaling. Mol. Biol. Cell 14, 2921-2934 (2003).
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 2921-2934
-
-
Nakazawa, T.1
|