Subchronic alpha-linolenic acid treatment enhances brain plasticity and exerts an antidepressant effect: A versatile potential therapy for stroke

Neuropsychopharmacology

Volumn 34, Issue 12, 2009, Pages 2548-2559

  Blondeau, Nicolas ^a,b   Nguemeni, Carine ^a   Debruyne, David N ^a   Piens, Marie ^c   Wu, Xuan ^d   Pan, Hongna ^d   Hu, Xian Zhang ^d   Gandin, Carine ^a   Lipsky, Robert H ^e,f   Plumier, Jean Christophe ^c   Marini, Ann M S ^d   Heurteaux, Catherine ^a,b  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b UNIVERSITÉ CÔTE D'AZUR   (France)

^c UNIVERSITY OF LIÈGE   (Belgium)

^d UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^e INOVA FAIRFAX HOSPITAL   (United States)

^f GEORGE MASON UNIVERSITY   (United States)

Author keywords

Alpha linolenic acid; Antidepressant effects; BDNF; Neurogenesis; Stroke; Synaptogenesis

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 2; LINOLENIC ACID; OMEGA 3 FATTY ACID; SYNAPTOBREVIN 2; SYNAPTOPHYSIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; STROKE;

ALPHA-LINOLENIC ACID; ANIMALS; BRAIN; CELLS, CULTURED; DEPRESSION; HIPPOCAMPUS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MICE; MICE, INBRED C57BL; NEUROGENESIS; NEURONAL PLASTICITY; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; STROKE; SYNAPSES; SYNAPTIC VESICLES;

EID: 70350066366     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2009.84     Document Type: Article

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