-
1
-
-
33749037701
-
Mechanism of homologous recombination: mediators and helicases take on regulatory functions
-
Sung P., and Klein H. Mechanism of homologous recombination: mediators and helicases take on regulatory functions. Nat. Rev., Mol. Cell Biol. 7 (2006) 739-750
-
(2006)
Nat. Rev., Mol. Cell Biol.
, vol.7
, pp. 739-750
-
-
Sung, P.1
Klein, H.2
-
2
-
-
0006713602
-
Identification of the breast cancer susceptibility gene BRCA2
-
Wooster R., Bignell G., Lancaster J., Swift S., Seal S., Mangion J., et al. Identification of the breast cancer susceptibility gene BRCA2. Nature 378 (1995) 789-792
-
(1995)
Nature
, vol.378
, pp. 789-792
-
-
Wooster, R.1
Bignell, G.2
Lancaster, J.3
Swift, S.4
Seal, S.5
Mangion, J.6
-
3
-
-
36949026476
-
BRCA2: a universal recombinase regulator
-
Thorslund T., and West S.C. BRCA2: a universal recombinase regulator. Oncogene 26 (2007) 7720-7730
-
(2007)
Oncogene
, vol.26
, pp. 7720-7730
-
-
Thorslund, T.1
West, S.C.2
-
4
-
-
14144253362
-
Cancer: catalyst of a catalyst
-
Kowalczykowski S.C. Cancer: catalyst of a catalyst. Nature 433 (2005) 591-592
-
(2005)
Nature
, vol.433
, pp. 591-592
-
-
Kowalczykowski, S.C.1
-
5
-
-
2242443513
-
Insights into DNA recombination from the structure of a Rad51-BRCA2 complex
-
Pellegrini L., Yu D.S., Lo T., Anand S., Lee M., Blundell T.L., and Venkitaraman A.R. Insights into DNA recombination from the structure of a Rad51-BRCA2 complex. Nature 420 (2002) 287-293
-
(2002)
Nature
, vol.420
, pp. 287-293
-
-
Pellegrini, L.1
Yu, D.S.2
Lo, T.3
Anand, S.4
Lee, M.5
Blundell, T.L.6
Venkitaraman, A.R.7
-
6
-
-
0035030368
-
Breast cancer genetics: what we know and what we need
-
Nathanson K.L., Wooster R., and Weber B.L. Breast cancer genetics: what we know and what we need. Nat. Med. 7 (2001) 552-556
-
(2001)
Nat. Med.
, vol.7
, pp. 552-556
-
-
Nathanson, K.L.1
Wooster, R.2
Weber, B.L.3
-
7
-
-
0035099044
-
BRCA2 is required for homology-directed repair of chromosomal breaks
-
Moynahan M.E., Pierce A.J., and Jasin M. BRCA2 is required for homology-directed repair of chromosomal breaks. Mol. Cell 7 (2001) 263-272
-
(2001)
Mol. Cell
, vol.7
, pp. 263-272
-
-
Moynahan, M.E.1
Pierce, A.J.2
Jasin, M.3
-
8
-
-
0037115914
-
Homologous repair of DNA damage and tumorigenesis: the BRCA connection
-
Jasin M. Homologous repair of DNA damage and tumorigenesis: the BRCA connection. Oncogene 21 (2002) 8981-8993
-
(2002)
Oncogene
, vol.21
, pp. 8981-8993
-
-
Jasin, M.1
-
9
-
-
0041378027
-
Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer
-
Lo T., Pellegrini L., Venkitaraman A.R., and Blundell T.L. Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer. DNA Repair (Amst.) 2 (2003) 1015-1028
-
(2003)
DNA Repair (Amst.)
, vol.2
, pp. 1015-1028
-
-
Lo, T.1
Pellegrini, L.2
Venkitaraman, A.R.3
Blundell, T.L.4
-
10
-
-
0035105999
-
Role of BRCA2 in control of the RAD51 recombination and DNA repair protein
-
Davies A.A., Masson J.Y., McIlwraith M.J., Stasiak A.Z., Stasiak A., Venkitaraman A.R., and West S.C. Role of BRCA2 in control of the RAD51 recombination and DNA repair protein. Mol. Cell 7 (2001) 273-282
-
(2001)
Mol. Cell
, vol.7
, pp. 273-282
-
-
Davies, A.A.1
Masson, J.Y.2
McIlwraith, M.J.3
Stasiak, A.Z.4
Stasiak, A.5
Venkitaraman, A.R.6
West, S.C.7
-
11
-
-
0030140414
-
Internal repeats in the BRCA2 protein sequence
-
Bork P., Blomberg N., and Nilges M. Internal repeats in the BRCA2 protein sequence. Nat. Genet. 13 (1996) 22-23
-
(1996)
Nat. Genet.
, vol.13
, pp. 22-23
-
-
Bork, P.1
Blomberg, N.2
Nilges, M.3
-
12
-
-
42449098062
-
Inhibition of filament formation of human Rad51 protein by a small peptide derived from the BRC-motif of the BRCA2 protein
-
Nomme J., Takizawa Y., Martinez S.F., Renodon-Corniere A., Fleury F., Weigel P., et al. Inhibition of filament formation of human Rad51 protein by a small peptide derived from the BRC-motif of the BRCA2 protein. Genes Cells 13 (2008) 471-481
-
(2008)
Genes Cells
, vol.13
, pp. 471-481
-
-
Nomme, J.1
Takizawa, Y.2
Martinez, S.F.3
Renodon-Corniere, A.4
Fleury, F.5
Weigel, P.6
-
13
-
-
34249887673
-
Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats
-
Davies O.R., and Pellegrini L. Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats. Nat. Struct. Mol. Biol. 14 (2007) 475-483
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 475-483
-
-
Davies, O.R.1
Pellegrini, L.2
-
14
-
-
34249878748
-
Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2
-
Esashi F., Galkin V.E., Yu X., Egelman E.H., and West S.C. Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2. Nat. Struct. Mol. Biol. 14 (2007) 468-474
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 468-474
-
-
Esashi, F.1
Galkin, V.E.2
Yu, X.3
Egelman, E.H.4
West, S.C.5
-
15
-
-
62149104415
-
The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51
-
Carreira A., Hilario J., Amitani I., Baskin R.J., Shivji M.K., Venkitaraman A.R., and Kowalczykowski S.C. The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51. Cell 136 (2009) 1032-1043
-
(2009)
Cell
, vol.136
, pp. 1032-1043
-
-
Carreira, A.1
Hilario, J.2
Amitani, I.3
Baskin, R.J.4
Shivji, M.K.5
Venkitaraman, A.R.6
Kowalczykowski, S.C.7
-
16
-
-
33748559470
-
A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange
-
Shivji M.K., Davies O.R., Savill J.M., Bates D.L., Pellegrini L., and Venkitaraman A.R. A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange. Nucleic Acids Res. 34 (2006) 4000-4011
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 4000-4011
-
-
Shivji, M.K.1
Davies, O.R.2
Savill, J.M.3
Bates, D.L.4
Pellegrini, L.5
Venkitaraman, A.R.6
-
17
-
-
63049108452
-
Linking the cellular functions of BRCA genes to cancer pathogenesis and treatment
-
Venkitaraman A.R. Linking the cellular functions of BRCA genes to cancer pathogenesis and treatment. Ann. Rev. Pathol. Mech. Dis. 4 (2009) 461-487
-
(2009)
Ann. Rev. Pathol. Mech. Dis.
, vol.4
, pp. 461-487
-
-
Venkitaraman, A.R.1
-
18
-
-
0035979246
-
Effects of DNA sequence and structure on binding of RecA to single-stranded DNA
-
Bar-Ziv R., and Libchaber A. Effects of DNA sequence and structure on binding of RecA to single-stranded DNA. Proc. Natl Acad. Sci. USA 98 (2001) 9068-9073
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 9068-9073
-
-
Bar-Ziv, R.1
Libchaber, A.2
-
19
-
-
0035053510
-
Effect of ions and nucleotides on the interactions of yeast Rad51 protein with single-stranded oligonucleotides
-
Kim J.M., Maraboeuf F., Kim S.K., Shinohara A., and Takahashi M. Effect of ions and nucleotides on the interactions of yeast Rad51 protein with single-stranded oligonucleotides. J. Biochem. 129 (2001) 469-475
-
(2001)
J. Biochem.
, vol.129
, pp. 469-475
-
-
Kim, J.M.1
Maraboeuf, F.2
Kim, S.K.3
Shinohara, A.4
Takahashi, M.5
-
20
-
-
0035937811
-
Basis for avid homologous DNA strand exchange by human Rad51 and RPA
-
Sigurdsson S., Trujillo K., Song B., Stratton S., and Sung P. Basis for avid homologous DNA strand exchange by human Rad51 and RPA. J. Biol. Chem. 276 (2001) 8798-8806
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 8798-8806
-
-
Sigurdsson, S.1
Trujillo, K.2
Song, B.3
Stratton, S.4
Sung, P.5
-
21
-
-
0030584084
-
Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro
-
Baumann P., Benson F.E., and West S.C. Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro. Cell 87 (1996) 757-766
-
(1996)
Cell
, vol.87
, pp. 757-766
-
-
Baumann, P.1
Benson, F.E.2
West, S.C.3
-
22
-
-
0034161571
-
Tailed duplex DNA is the preferred substrate for Rad51 protein-mediated homologous pairing
-
Mazin A.V., Zaitseva E., Sung P., and Kowalczykowski S.C. Tailed duplex DNA is the preferred substrate for Rad51 protein-mediated homologous pairing. EMBO J. 19 (2000) 1148-1156
-
(2000)
EMBO J.
, vol.19
, pp. 1148-1156
-
-
Mazin, A.V.1
Zaitseva, E.2
Sung, P.3
Kowalczykowski, S.C.4
-
24
-
-
0029398141
-
Hybridization of fluorescein-labeled DNA oligomers detected by fluorescence anisotropy with protein binding enhancement
-
Kumke M.U., Li G., McGown L.B., Walker G.T., and Linn C.P. Hybridization of fluorescein-labeled DNA oligomers detected by fluorescence anisotropy with protein binding enhancement. Anal. Chem. 67 (1995) 3945-3951
-
(1995)
Anal. Chem.
, vol.67
, pp. 3945-3951
-
-
Kumke, M.U.1
Li, G.2
McGown, L.B.3
Walker, G.T.4
Linn, C.P.5
-
25
-
-
33744950933
-
Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide
-
San Filippo J., Chi P., Sehorn M.G., Etchin J., Krejci L., and Sung P. Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide. J. Biol. Chem. 281 (2006) 11649-11657
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 11649-11657
-
-
San Filippo, J.1
Chi, P.2
Sehorn, M.G.3
Etchin, J.4
Krejci, L.5
Sung, P.6
-
26
-
-
0032702679
-
Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control
-
Chen C.F., Chen P.L., Zhong Q., Sharp Z.D., and Lee W.H. Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control. J. Biol. Chem. 274 (1999) 32931-32935
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32931-32935
-
-
Chen, C.F.1
Chen, P.L.2
Zhong, Q.3
Sharp, Z.D.4
Lee, W.H.5
-
27
-
-
34250879021
-
Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1
-
Thorslund T., Esashi F., and West S.C. Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1. EMBO J. 26 (2007) 2915-2922
-
(2007)
EMBO J.
, vol.26
, pp. 2915-2922
-
-
Thorslund, T.1
Esashi, F.2
West, S.C.3
-
28
-
-
20844443496
-
BRCA2 BRC motifs bind RAD51-DNA filaments
-
Galkin V.E., Esashi F., Yu X., Yang S., West S.C., and Egelman E.H. BRCA2 BRC motifs bind RAD51-DNA filaments. Proc. Natl Acad. Sci. USA 102 (2005) 8537-8542
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 8537-8542
-
-
Galkin, V.E.1
Esashi, F.2
Yu, X.3
Yang, S.4
West, S.C.5
Egelman, E.H.6
-
29
-
-
49649088827
-
Classical molecular dynamics simulations of the complex between the RAD51 protein and the BRC hairpin loops of the BRCA2 protein
-
Buis N., Skylaris C.K., Grant G.H., Rajendra E., Payne M.C., and Venkitaraman A.R. Classical molecular dynamics simulations of the complex between the RAD51 protein and the BRC hairpin loops of the BRCA2 protein. Mol. Simul. 34 (2008) 749-759
-
(2008)
Mol. Simul.
, vol.34
, pp. 749-759
-
-
Buis, N.1
Skylaris, C.K.2
Grant, G.H.3
Rajendra, E.4
Payne, M.C.5
Venkitaraman, A.R.6
-
31
-
-
46249091563
-
The checkpoint kinases Chk1 and Chk2 regulate the functional associations between hBRCA2 and Rad51 in response to DNA damage
-
Bahassi E.M., Ovesen J.L., Riesenberg A.L., Bernstein W.Z., Hasty P.E., and Stambrook P.J. The checkpoint kinases Chk1 and Chk2 regulate the functional associations between hBRCA2 and Rad51 in response to DNA damage. Oncogene 27 (2008) 3977-3985
-
(2008)
Oncogene
, vol.27
, pp. 3977-3985
-
-
Bahassi, E.M.1
Ovesen, J.L.2
Riesenberg, A.L.3
Bernstein, W.Z.4
Hasty, P.E.5
Stambrook, P.J.6
-
32
-
-
18544372595
-
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
-
Yang H., Jeffrey P.D., Miller J., Kinnucan E., Sun Y., Thoma N.H., et al. BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure. Science 297 (2002) 1837-1848
-
(2002)
Science
, vol.297
, pp. 1837-1848
-
-
Yang, H.1
Jeffrey, P.D.2
Miller, J.3
Kinnucan, E.4
Sun, Y.5
Thoma, N.H.6
-
33
-
-
33745018564
-
Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions
-
Saeki H., Siaud N., Christ N., Wiegant W.W., van Buul P.P., Han M., et al. Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions. Proc. Natl Acad. Sci. USA 103 (2006) 8768-8773
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 8768-8773
-
-
Saeki, H.1
Siaud, N.2
Christ, N.3
Wiegant, W.W.4
van Buul, P.P.5
Han, M.6
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