BRCA2 BRC motifs bind RAD51-DNA filaments

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 24, 2005, Pages 8537-8542

  Galkin, Vitold E ^a   Esashi, Fumiko ^b   Yu, Xiong ^a   Yang, Shixin ^a   West, Stephen C ^b   Egelman, Edward H ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Electron microscopy; Genome stability and dynamics; Nucleoprotein filaments; Recombination; Structural biology

Indexed keywords

BRC3 PROTEIN; BRC4 PROTEIN; BRCA2 PROTEIN; DNA; NUCLEOPROTEIN; RAD51 PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; AUTOSOMAL DOMINANT DISORDER; BREAST CANCER; BREAST CARCINOGENESIS; CANCER RISK; COMPLEX FORMATION; DNA DAMAGE; ELECTRON MICROSCOPY; GENE MUTATION; GENETIC RECOMBINATION; GENETIC STABILITY; GENOMIC INSTABILITY; GERM LINE; HUMAN; MOLECULAR DYNAMICS; NUCLEOTIDE REPEAT; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN MOTIF;

BRCA2 PROTEIN; DNA; DNA-BINDING PROTEINS; ELECTROPHORESIS; GLUTATHIONE TRANSFERASE; HUMANS; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RAD51 RECOMBINASE; TANDEM REPEAT SEQUENCES;

EID: 20844443496     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0407266102     Document Type: Article

References (45)

1. Esashi, F., Christ, N., Gannon, J., Liu, Y., Hunt, T., Jasin, M. & West, S. C. (2005) Nature 434, 598-604.
2. Chen, P. L., Chen, C. F., Chen, Y., Xiao, J., Sharp, Z. D. & Lee, W. H. (1998) Proc. Natl. Acad. Sci. USA 95, 5287-5292.
3. Wong, A. K., Pero, R., Ormonde, P. A., Tavtigian, S. V. & Bartel, P. L. (1997) J. Biol. Chem. 272, 31941-31944.
4. Donoho, G., Brenneman, M. A., Cui, T. X., Donoviel, D., Vogel, H., Goodwin, E. H., Chen, D. J. & Hasty, P. (2003) Genes Chromosomes Cancer 36, 317-331.
5. Chen, F. M., Hou, M. F., Chang, M. Y., Wang, J. Y., Hsieh, J. S., Ou-Yang, F., Huang, T. J. & Lin, S. R. (2005) Cancer Lett. 220, 177-184.
6. Lo, T., Pellegrini, L., Venkitaraman, A. R. & Blundell, T. L. (2003) DNA Repair 2, 1015-1028.
7. Kojic, M., Kostrub, C. F., Buchman, A. R. & Holloman, W. K. (2002) Mol. Cell 10, 683-691.
8. Sharan, S. K., Morimatsu, M., Albrecht, U., Lim, D. S., Regel, E., Dinh, C., Sands, A., Eichele, G., Hasty, P. & Bradley, A. (1997) Nature 386, 804-810.
9. Pellegrini, L., Yu, D. S., Lo, T., Anand, S., Lee, M., Blundell, T. L. & Venkitaraman, A. R. (2002) Nature 420, 287-293.
10. Davies, A. A., Masson, J. Y., McIlwraith, M. J., Stasiak, A. Z., Stasiak, A., Venkitaraman, A. R. & West, S. C. (2001) Mol. Cell 7, 273-282.
11. Powell, S. N. & Kachnic, L. A. (2003) Oncogene 22, 5784-5791.
12. Yang, H., Li, Q., Fan, J., Holloman, W. K. & Pavletich, N. P. (2005) Nature 433, 653-657.
13. Baumann, P., Benson, F. E., Hajibagheri, N. & West, S. C. (1997) Mutat. Res. 384, 65-72.
14. Lee, M., Daniels, M. J. & Venkitaraman, A. R. (2004) Oncogene 23, 865-872.
15. Orlova, A. & Egelman, E. H. (1997) J. Mol. Biol. 265, 469-474.
16. Egelman, E. H. (2000) Ultramicroscopy 85, 225-234.
17. Conway, A. B., Lynch, T. W., Zhang, Y., Fortin, G. S., Fung, C. W., Symington, L. S. & Rice, P. A. (2004) Nat. Struct. Mol. Biol. 11, 791-796.
18. Yang, S., Yu, X., Seitz, E. M., Kowalczykowski, S. C. & Egelman, E. H. (2001) J. Mol. Biol. 314, 1077-1085.
19. Shin, D. S., Pellegrini, L., Daniels, D. S., Yelent, B., Craig, L., Bates, D., Yu, D. S., Shivji, M. K., Hitomi, C., Arvai, A. S., et al. (2003) EMBO J. 22, 4566-4576.
20. Kinebuchi, T., Kagawa, W., Enomoto, R., Tanaka, K., Miyagawa, K., Shibata, T., Kurumizaka, H. & Yokoyama, S. (2004) Mol. Cell 14, 363-374.
21. Siaud, N., Dray, E., Gy, I., Gerard, E., Takvorian, N. & Doutriaux, M. P. (2004) EMBO J. 23, 1392-1401.
22. Tarsounas, M., Davies, D. & West, S. C. (2003) Oncogene 22, 1115-1123.
23. Yasuda, T., Morimatsu, K., Horii, T., Nagata, T. & Ohmori, H. (1998) EMBO J. 17, 3207-3216.
24. Voloshin, O. N., Ramirez, B. E., Bax, A. & Camerini-Otero, R. D. (2001) Genes Dev. 15, 415-427.
25. Yasuda, T., Morimatsu, K., Kato, R., Usukura, J., Takahashi, M. & Ohmori, H. (2001) EMBO J. 20, 1192-1202.
26. Lusetti, S. L., Voloshin, O. N., Inman, R. B., Camerini-Otero, R. D. & Cox, M. M. (2004) J. Biol. Chem. 279, 30037-30046.
27. Aihara, H., Ito, Y., Kurumizaka, H., Yokoyama, S. & Shibata, T. (1999) J. Mol. Biol. 290, 495-504.
28. Aihara, H., Ito, Y., Kurumizaka, H., Terada, T., Yokoyama, S. & Shibata, T. (1997) J. Mol. Biol. 274, 213-221.
29. Pollard, T. D., Blanchoin, L. & Mullins, R. D. (2000) Annu. Rev. Biophys. Biomol. Struct. 29, 545-576.
30. Lilic, M., Galkin, V. E., Orlova, A., VanLoock, M. S., Egelman, E. H. & Stebbins, C. E. (2003) Science 301, 1918-1921.
31. Chen, H., Bernstein, B. W. & Bamburg, J. R. (2000) Trends Biochem. Sci. 25, 19-23.
32. Yeoh, S., Pope, B., Mannherz, H. G. & Weeds, A. (2002) J. Mol. Biol. 315, 911-925.
33. Burtnick, L. D., Koepf, E. K., Grimes, J., Jones, E. Y., Stuart, D. I., McLaughlin, P. J. & Robinson, R. C. (1997) Cell 90, 661-670.
34. Maytum, R., Lehrer, S. S. & Geeves, M. A. (1999) Biochemistry 38, 1102-1110.
35. Hitchcock-DeGregori, S. E., Sampath, P. & Pollard, T. D. (1988) Biochemistry 27, 9182-9185.
36. Ono, S. & Ono, K. (2002) J. Cell Biol. 156, 1065-1076.
37. Hitchcock-DeGregori, S. E., Song, Y. & Greenfield, N. J. (2002) Biochemistry 41, 15036-15044.
38. Root, D. D. & Wang, K. (2001) Biochemistry 40, 1171-1186.
39. Yu, X., VanLoock, M. S., Yang, S., Reese, J. T. & Egelman, E. H. (2004) Curr. Protein Pept. Sci. 5, 73-79.
40. Karlin, S., Weinstock, G. M. & Brendel, V. (1995) J. Bacteriol. 177, 6881-6893.
41. Story, R. M., Weber, I. T. & Steitz, T. A. (1992) Nature 355, 318-325.
42. Wu, Y., He, Y., Moya, I. A., Qian, X. & Luo, Y. (2004) Mol. Cell 15, 423-435.
43. VanLoock, M. S., Yu, X., Yang, S., Lai, A. L., Low, C., Campbell, M. J. & Egelman, E. H. (2003) Structure (London) 11, 187-196.
44. Yu, X., Jacobs, S. A., West, S. C., Ogawa, T. & Egelman, E. H. (2001) Proc. Natl. Acad. Sci. USA 98, 8419-8424.
45. Kudryashov, D. S., Phillips, M. & Reisler, E. (2004) Biophys. J. 87, 1136-1145.