Anthrax lethal toxin enhances IκB kinase activation and differentially regulates pro-inflammatory genes in human endothelium

Journal of Biological Chemistry

Volumn 284, Issue 38, 2009, Pages 25761-25771

  Warfel, Jason M ^a,b   D'Agnillo, Felice ^a,c  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATOR PROTEIN-1; CUMULATIVE EFFECTS; HOST RESPONSE; HUMAN ENDOTHELIAL CELLS; INFLAMMATORY GENES; INHIBITORY PROTEINS; KINASE ACTIVATION; KINASE COMPLEX; MECHANISTIC LINK; NET EFFECT; PROINFLAMMATORY; REGULATED GENES; TRANSCRIPTIONAL ACTIVITY; TUMOR NECROSIS FACTORS;

CHEMICAL ACTIVATION; DEGRADATION; ENDOTHELIAL CELLS; GENES; TRANSCRIPTION FACTORS;

TRANSCRIPTION;

ANTHRAX TOXIN; CD40 ANTIGEN; I KAPPA B ALPHA; I KAPPA B KINASE; MACROPHAGE DERIVED CHEMOKINE; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSCRIPTION FACTOR AP 1; BACTERIAL ANTIGEN; BACTERIAL TOXIN; CCL2 PROTEIN, HUMAN; I KAPPA B; I KAPPA B BETA; RELA PROTEIN, HUMAN; TRANSCRIPTION FACTOR RELA;

ARTICLE; CONTROLLED STUDY; ENDOTHELIUM; ENZYME ACTIVATION; ENZYME SUBSTRATE; GENE CONTROL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLAMMATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; TOXIN ANALYSIS; TRANSCRIPTION REGULATION; ANTHRAX; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; ENDOTHELIUM CELL; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; METABOLISM; VASCULAR ENDOTHELIUM;

ANTHRAX; ANTIGENS, BACTERIAL; ANTIGENS, CD40; BACTERIAL TOXINS; CELLS, CULTURED; CHEMOKINE CCL2; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B KINASE; I-KAPPA B PROTEINS; INFLAMMATION; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION, GENETIC;

EID: 70350020715     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.036970     Document Type: Article

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