메뉴 건너뛰기




Volumn 15, Issue 10, 2009, Pages 439-451

The neurovascular link in health and disease: an update

Author keywords

[No Author keywords available]

Indexed keywords

EPHRIN; ERYTHROPOIETIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GRANULOCYTE COLONY STIMULATING FACTOR; NETRIN; NITRIC OXIDE; ROUNDABOUT RECEPTOR; SLIT PROTEIN; VASCULOTROPIN; VASCULOTROPIN A;

EID: 70350018469     PISSN: 14714914     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molmed.2009.08.005     Document Type: Review
Times cited : (66)

References (138)
  • 1
    • 22444447946 scopus 로고    scopus 로고
    • Common mechanisms of nerve and blood vessel wiring
    • Carmeliet P., and Tessier-Lavigne M. Common mechanisms of nerve and blood vessel wiring. Nature 436 (2005) 193-200
    • (2005) Nature , vol.436 , pp. 193-200
    • Carmeliet, P.1    Tessier-Lavigne, M.2
  • 2
    • 61949107700 scopus 로고    scopus 로고
    • Guidance of vascular development: lessons from the nervous system
    • Larrivee B., et al. Guidance of vascular development: lessons from the nervous system. Circ. Res. 104 (2009) 428-441
    • (2009) Circ. Res. , vol.104 , pp. 428-441
    • Larrivee, B.1
  • 3
    • 65549135834 scopus 로고    scopus 로고
    • Mechanisms of vessel branching. Filopodia on endothelial tip cells lead the way
    • De Smet F., et al. Mechanisms of vessel branching. Filopodia on endothelial tip cells lead the way. Arterioscler. Thromb. Vasc. Biol. 29 (2009) 639-649
    • (2009) Arterioscler. Thromb. Vasc. Biol. , vol.29 , pp. 639-649
    • De Smet, F.1
  • 4
    • 39449111508 scopus 로고    scopus 로고
    • Neurovascular signalling defects in neurodegeneration
    • Zacchigna S., et al. Neurovascular signalling defects in neurodegeneration. Nat. Rev. Neurosci. 9 (2008) 169-181
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 169-181
    • Zacchigna, S.1
  • 5
    • 49949152069 scopus 로고    scopus 로고
    • Mechanisms of adaptive angiogenesis to tissue hypoxia
    • Fong G.H. Mechanisms of adaptive angiogenesis to tissue hypoxia. Angiogenesis 11 (2008) 121-140
    • (2008) Angiogenesis , vol.11 , pp. 121-140
    • Fong, G.H.1
  • 6
    • 48149113439 scopus 로고    scopus 로고
    • Oxygen levels affect axon guidance and neuronal migration in Caenorhabditis elegans
    • Pocock R., and Hobert O. Oxygen levels affect axon guidance and neuronal migration in Caenorhabditis elegans. Nat. Neurosci. 11 (2008) 894-900
    • (2008) Nat. Neurosci. , vol.11 , pp. 894-900
    • Pocock, R.1    Hobert, O.2
  • 7
    • 0041378074 scopus 로고    scopus 로고
    • Blood vessels and nerves: common signals, pathways and diseases
    • Carmeliet P. Blood vessels and nerves: common signals, pathways and diseases. Nat. Rev. Genet. 4 (2003) 710-720
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 710-720
    • Carmeliet, P.1
  • 8
    • 35548969443 scopus 로고    scopus 로고
    • Glial regulation of the cerebral microvasculature
    • Iadecola C., and Nedergaard M. Glial regulation of the cerebral microvasculature. Nat. Neurosci. 10 (2007) 1369-1376
    • (2007) Nat. Neurosci. , vol.10 , pp. 1369-1376
    • Iadecola, C.1    Nedergaard, M.2
  • 9
    • 36448982477 scopus 로고    scopus 로고
    • Brain micro-ecologies: neural stem cell niches in the adult mammalian brain
    • Riquelme P.A., et al. Brain micro-ecologies: neural stem cell niches in the adult mammalian brain. Philos. Trans. R Soc. Lond. B Biol. Sci. 363 (2008) 123-137
    • (2008) Philos. Trans. R Soc. Lond. B Biol. Sci. , vol.363 , pp. 123-137
    • Riquelme, P.A.1
  • 10
    • 13544268809 scopus 로고    scopus 로고
    • Neurovascular mechanisms of Alzheimer's neurodegeneration
    • Zlokovic B.V. Neurovascular mechanisms of Alzheimer's neurodegeneration. Trends Neurosci. 28 (2005) 202-208
    • (2005) Trends Neurosci. , vol.28 , pp. 202-208
    • Zlokovic, B.V.1
  • 11
    • 41149097086 scopus 로고    scopus 로고
    • ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration
    • Zhong Z., et al. ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration. Nat. Neurosci. 11 (2008) 420-422
    • (2008) Nat. Neurosci. , vol.11 , pp. 420-422
    • Zhong, Z.1
  • 12
    • 67649973540 scopus 로고    scopus 로고
    • Role and therapeutic potential of VEGF in the nervous system
    • Ruiz de Almodovar C., et al. Role and therapeutic potential of VEGF in the nervous system. Physiol. Rev. 89 (2009) 607-648
    • (2009) Physiol. Rev. , vol.89 , pp. 607-648
    • Ruiz de Almodovar, C.1
  • 13
    • 41049099329 scopus 로고    scopus 로고
    • Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis
    • Geretti E., et al. Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis. Angiogenesis 11 (2008) 31-39
    • (2008) Angiogenesis , vol.11 , pp. 31-39
    • Geretti, E.1
  • 14
    • 0034282885 scopus 로고    scopus 로고
    • The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor flt-1
    • Fuh G., et al. The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor flt-1. J. Biol. Chem. 275 (2000) 26690-26695
    • (2000) J. Biol. Chem. , vol.275 , pp. 26690-26695
    • Fuh, G.1
  • 15
    • 1542571789 scopus 로고    scopus 로고
    • Neuropilin-1-mediated vascular permeability factor/vascular endothelial growth factor-dependent endothelial cell migration
    • Wang L., et al. Neuropilin-1-mediated vascular permeability factor/vascular endothelial growth factor-dependent endothelial cell migration. J. Biol. Chem. 278 (2003) 48848-48860
    • (2003) J. Biol. Chem. , vol.278 , pp. 48848-48860
    • Wang, L.1
  • 16
    • 43149106665 scopus 로고    scopus 로고
    • Neuropilin-1 modulates p53/caspases axis to promote endothelial cell survival
    • Wang L., et al. Neuropilin-1 modulates p53/caspases axis to promote endothelial cell survival. PLoS ONE 2 (2007) e1161
    • (2007) PLoS ONE , vol.2
    • Wang, L.1
  • 17
    • 14944344614 scopus 로고    scopus 로고
    • Neuropilin-1 regulates attachment in human endothelial cells independently of vascular endothelial growth factor receptor-2
    • Murga M., et al. Neuropilin-1 regulates attachment in human endothelial cells independently of vascular endothelial growth factor receptor-2. Blood 105 (2005) 1992-1999
    • (2005) Blood , vol.105 , pp. 1992-1999
    • Murga, M.1
  • 18
    • 67650487559 scopus 로고    scopus 로고
    • VEGFR-1 regulates adult olfactory bulb neurogenesis and migration of neural progenitors in the rostral migratory stream in vivo
    • Wittko I.M., et al. VEGFR-1 regulates adult olfactory bulb neurogenesis and migration of neural progenitors in the rostral migratory stream in vivo. J. Neurosci. 29 (2009) 8704-8714
    • (2009) J. Neurosci. , vol.29 , pp. 8704-8714
    • Wittko, I.M.1
  • 19
    • 51649123294 scopus 로고    scopus 로고
    • Re-evaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium
    • Li X., et al. Re-evaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium. Arterioscler Thromb. Vasc. Biol. 28 (2008) 1614-1620
    • (2008) Arterioscler Thromb. Vasc. Biol. , vol.28 , pp. 1614-1620
    • Li, X.1
  • 20
    • 4944253249 scopus 로고    scopus 로고
    • Increased severity of cerebral ischemic injury in vascular endothelial growth factor-B-deficient mice
    • Sun Y., et al. Increased severity of cerebral ischemic injury in vascular endothelial growth factor-B-deficient mice. J. Cereb. Blood Flow Metab. 24 (2004) 1146-1152
    • (2004) J. Cereb. Blood Flow Metab. , vol.24 , pp. 1146-1152
    • Sun, Y.1
  • 21
    • 33344460695 scopus 로고    scopus 로고
    • VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain
    • Le Bras B., et al. VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain. Nat. Neurosci. 9 (2006) 340-348
    • (2006) Nat. Neurosci. , vol.9 , pp. 340-348
    • Le Bras, B.1
  • 22
    • 4344638498 scopus 로고    scopus 로고
    • Semaphorins guide PerPlexeD endothelial cells
    • Deutsch U. Semaphorins guide PerPlexeD endothelial cells. Dev. Cell 7 (2004) 1-2
    • (2004) Dev. Cell , vol.7 , pp. 1-2
    • Deutsch, U.1
  • 23
    • 60549094267 scopus 로고    scopus 로고
    • The plexin-A1 receptor activates vascular endothelial growth factor-receptor 2 and nuclear factor-kappaB to mediate survival and anchorage-independent growth of malignant mesothelioma cells
    • Catalano A., et al. The plexin-A1 receptor activates vascular endothelial growth factor-receptor 2 and nuclear factor-kappaB to mediate survival and anchorage-independent growth of malignant mesothelioma cells. Cancer Res. 69 (2009) 1485-1493
    • (2009) Cancer Res. , vol.69 , pp. 1485-1493
    • Catalano, A.1
  • 24
    • 53249096017 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and semaphorin induce neuropilin-1 endocytosis via separate pathways
    • Salikhova A., et al. Vascular endothelial growth factor and semaphorin induce neuropilin-1 endocytosis via separate pathways. Circ Res. 103 (2008) e71-79
    • (2008) Circ Res. , vol.103
    • Salikhova, A.1
  • 25
    • 33747165872 scopus 로고    scopus 로고
    • Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments
    • Lampugnani M.G., et al. Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments. J. Cell Biol. 174 (2006) 593-604
    • (2006) J. Cell Biol. , vol.174 , pp. 593-604
    • Lampugnani, M.G.1
  • 26
    • 36549056078 scopus 로고    scopus 로고
    • Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
    • Appleton B.A., et al. Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding. Embo. J. 26 (2007) 4902-4912
    • (2007) Embo. J. , vol.26 , pp. 4902-4912
    • Appleton, B.A.1
  • 27
    • 34250662228 scopus 로고    scopus 로고
    • Selective requirements for NRP1 ligands during neurovascular patterning
    • Vieira J.M., et al. Selective requirements for NRP1 ligands during neurovascular patterning. Development 134 (2007) 1833-1843
    • (2007) Development , vol.134 , pp. 1833-1843
    • Vieira, J.M.1
  • 28
    • 35348879042 scopus 로고    scopus 로고
    • Similarities between angiogenesis and neural development: what small animal models can tell us
    • Zacchigna S., et al. Similarities between angiogenesis and neural development: what small animal models can tell us. Curr. Top. Dev. Biol. 80 (2008) 1-55
    • (2008) Curr. Top. Dev. Biol. , vol.80 , pp. 1-55
    • Zacchigna, S.1
  • 29
    • 45449083263 scopus 로고    scopus 로고
    • DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1
    • Ly A., et al. DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1. Cell 133 (2008) 1241-1254
    • (2008) Cell , vol.133 , pp. 1241-1254
    • Ly, A.1
  • 30
    • 59749096364 scopus 로고    scopus 로고
    • Dscam guides embryonic axons by netrin-dependent and -independent functions
    • Andrews G.L., et al. Dscam guides embryonic axons by netrin-dependent and -independent functions. Development 135 (2008) 3839-3848
    • (2008) Development , vol.135 , pp. 3839-3848
    • Andrews, G.L.1
  • 31
    • 62449095973 scopus 로고    scopus 로고
    • Discovery of a functional protein complex of netrin-4, laminin gamma1 chain, and integrin alpha6beta1 in mouse neural stem cells
    • Staquicini F.I., et al. Discovery of a functional protein complex of netrin-4, laminin gamma1 chain, and integrin alpha6beta1 in mouse neural stem cells. Proc. Natl. Acad Sc.i U. S. A. 106 (2009) 2903-2908
    • (2009) Proc. Natl. Acad Sc.i U. S. A. , vol.106 , pp. 2903-2908
    • Staquicini, F.I.1
  • 32
    • 33846378156 scopus 로고    scopus 로고
    • Characterization of the receptors for axon guidance factor netrin-4 and identification of the binding domains
    • Qin S., et al. Characterization of the receptors for axon guidance factor netrin-4 and identification of the binding domains. Mol. Cell Neurosci. 34 (2007) 243-250
    • (2007) Mol. Cell Neurosci. , vol.34 , pp. 243-250
    • Qin, S.1
  • 33
    • 38449119610 scopus 로고    scopus 로고
    • Netrin-1-independent adenosine A2b receptor activation regulates the response of axons to netrin-1 by controlling cell surface levels of UNC5A receptors
    • McKenna W.L., et al. Netrin-1-independent adenosine A2b receptor activation regulates the response of axons to netrin-1 by controlling cell surface levels of UNC5A receptors. J. Neurochem. 104 (2008) 1081-1090
    • (2008) J. Neurochem. , vol.104 , pp. 1081-1090
    • McKenna, W.L.1
  • 34
    • 44649197812 scopus 로고    scopus 로고
    • Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B
    • Tang X., et al. Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B. Nat. Cell Biol. 10 (2008) 698-706
    • (2008) Nat. Cell Biol. , vol.10 , pp. 698-706
    • Tang, X.1
  • 35
    • 55749092294 scopus 로고    scopus 로고
    • Netrin-1 is a survival factor during commissural neuron navigation
    • Furne C., et al. Netrin-1 is a survival factor during commissural neuron navigation. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 14465-14470
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 14465-14470
    • Furne, C.1
  • 36
    • 64749115313 scopus 로고    scopus 로고
    • Inhibition of endothelial cell apoptosis by netrin-1 during angiogenesis
    • Castets M., et al. Inhibition of endothelial cell apoptosis by netrin-1 during angiogenesis. Dev. Cell 16 (2009) 614-620
    • (2009) Dev. Cell , vol.16 , pp. 614-620
    • Castets, M.1
  • 37
    • 8844281731 scopus 로고    scopus 로고
    • The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system
    • Lu X., et al. The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system. Nature 432 (2004) 179-186
    • (2004) Nature , vol.432 , pp. 179-186
    • Lu, X.1
  • 38
    • 33746878254 scopus 로고    scopus 로고
    • Netrins promote developmental and therapeutic angiogenesis
    • Wilson B.D., et al. Netrins promote developmental and therapeutic angiogenesis. Science 313 (2006) 640-644
    • (2006) Science , vol.313 , pp. 640-644
    • Wilson, B.D.1
  • 39
    • 50449110059 scopus 로고    scopus 로고
    • Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B
    • Lejmi E., et al. Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B. Proc. Natl. Acad Sci. U. S. A. 105 (2008) 12491-12496
    • (2008) Proc. Natl. Acad Sci. U. S. A. , vol.105 , pp. 12491-12496
    • Lejmi, E.1
  • 40
    • 59149088998 scopus 로고    scopus 로고
    • Netrin-4 enhances angiogenesis and neurologic outcome after cerebral ischemia
    • Hoang S., et al. Netrin-4 enhances angiogenesis and neurologic outcome after cerebral ischemia. J. Cereb. Blood Flow. Metab. 29 (2009) 385-397
    • (2009) J. Cereb. Blood Flow. Metab. , vol.29 , pp. 385-397
    • Hoang, S.1
  • 41
    • 55749097770 scopus 로고    scopus 로고
    • Slit and Robo regulate dendrite branching and elongation of space-filling neurons in Drosophila
    • Dimitrova S., et al. Slit and Robo regulate dendrite branching and elongation of space-filling neurons in Drosophila. Dev. Biol. 324 (2008) 18-30
    • (2008) Dev. Biol. , vol.324 , pp. 18-30
    • Dimitrova, S.1
  • 42
    • 34250837980 scopus 로고    scopus 로고
    • Dual branch-promoting and branch-repelling actions of Slit/Robo signaling on peripheral and central branches of developing sensory axons
    • Ma L., and Tessier-Lavigne M. Dual branch-promoting and branch-repelling actions of Slit/Robo signaling on peripheral and central branches of developing sensory axons. J. Neurosci. 27 (2007) 6843-6851
    • (2007) J. Neurosci. , vol.27 , pp. 6843-6851
    • Ma, L.1    Tessier-Lavigne, M.2
  • 43
    • 42949112638 scopus 로고    scopus 로고
    • Robos and Slits control the pathfinding and targeting of mouse olfactory sensory axons
    • Nguyen-Ba-Charvet K.T., et al. Robos and Slits control the pathfinding and targeting of mouse olfactory sensory axons. J. Neurosci. 28 (2008) 4244-4249
    • (2008) J. Neurosci. , vol.28 , pp. 4244-4249
    • Nguyen-Ba-Charvet, K.T.1
  • 44
    • 46749140885 scopus 로고    scopus 로고
    • Molecular mechanisms controlling midline crossing by precerebellar neurons
    • Di Meglio T., et al. Molecular mechanisms controlling midline crossing by precerebellar neurons. J. Neurosci. 28 (2008) 6285-6294
    • (2008) J. Neurosci. , vol.28 , pp. 6285-6294
    • Di Meglio, T.1
  • 45
    • 58149397961 scopus 로고    scopus 로고
    • Silencing of directional migration in roundabout4 knockdown endothelial cells
    • Kaur S., et al. Silencing of directional migration in roundabout4 knockdown endothelial cells. BMC Cell Biol. 9 (2008) 61
    • (2008) BMC Cell Biol. , vol.9 , pp. 61
    • Kaur, S.1
  • 46
    • 41049085947 scopus 로고    scopus 로고
    • Slits and Roundabouts in cancer, tumor angiogenesis and endothelial cell migration
    • Legg J.A., et al. Slits and Roundabouts in cancer, tumor angiogenesis and endothelial cell migration. Angiogenesis 11 (2008) 13-21
    • (2008) Angiogenesis , vol.11 , pp. 13-21
    • Legg, J.A.1
  • 47
    • 41849131420 scopus 로고    scopus 로고
    • Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability
    • Jones C.A., et al. Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability. Nat. Med. 14 (2008) 448-453
    • (2008) Nat. Med. , vol.14 , pp. 448-453
    • Jones, C.A.1
  • 48
    • 59649086084 scopus 로고    scopus 로고
    • Active involvement of Robo1 and Robo4 in filopodia formation and endothelial cell motility mediated via WASP and other actin nucleation-promoting factors
    • Sheldon H., et al. Active involvement of Robo1 and Robo4 in filopodia formation and endothelial cell motility mediated via WASP and other actin nucleation-promoting factors. Faseb. J. 23 (2009) 513-522
    • (2009) Faseb. J. , vol.23 , pp. 513-522
    • Sheldon, H.1
  • 49
    • 34247615569 scopus 로고    scopus 로고
    • Bidirectional Eph/ephrin signaling during axon guidance
    • Egea J., and Klein R. Bidirectional Eph/ephrin signaling during axon guidance. Trends Cell Biol. 17 (2007) 230-238
    • (2007) Trends Cell Biol. , vol.17 , pp. 230-238
    • Egea, J.1    Klein, R.2
  • 50
    • 41149084179 scopus 로고    scopus 로고
    • Eph/ephrin bidirectional signaling in physiology and disease
    • Pasquale E.B. Eph/ephrin bidirectional signaling in physiology and disease. Cell 133 (2008) 38-52
    • (2008) Cell , vol.133 , pp. 38-52
    • Pasquale, E.B.1
  • 51
    • 58149138860 scopus 로고    scopus 로고
    • Bidirectional modulation of synaptic functions by Eph/ephrin signaling
    • Klein R. Bidirectional modulation of synaptic functions by Eph/ephrin signaling. Nat. Neurosci. 12 (2009) 15-20
    • (2009) Nat. Neurosci. , vol.12 , pp. 15-20
    • Klein, R.1
  • 52
    • 34250223116 scopus 로고    scopus 로고
    • Regulation of angiogenesis by Eph/ephrin interactions
    • Kuijper S., et al. Regulation of angiogenesis by Eph/ephrin interactions. Trends Cardiovasc. Med. 17 (2007) 145-151
    • (2007) Trends Cardiovasc. Med. , vol.17 , pp. 145-151
    • Kuijper, S.1
  • 53
    • 39449085234 scopus 로고    scopus 로고
    • Eph/ephrin signaling: networks
    • Arvanitis D., and Davy A. Eph/ephrin signaling: networks. Genes Dev. 22 (2008) 416-429
    • (2008) Genes Dev. , vol.22 , pp. 416-429
    • Arvanitis, D.1    Davy, A.2
  • 54
    • 58149375273 scopus 로고    scopus 로고
    • A TrkB/ephrinA interaction controls retinal axon branching and synaptogenesis
    • Marler K.J., et al. A TrkB/ephrinA interaction controls retinal axon branching and synaptogenesis. J. Neurosci. 28 (2008) 12700-12712
    • (2008) J. Neurosci. , vol.28 , pp. 12700-12712
    • Marler, K.J.1
  • 55
    • 33646493863 scopus 로고    scopus 로고
    • Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb
    • Kramer E.R., et al. Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb. Neuron 50 (2006) 35-47
    • (2006) Neuron , vol.50 , pp. 35-47
    • Kramer, E.R.1
  • 56
    • 30344440869 scopus 로고    scopus 로고
    • Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly
    • Foo S.S., et al. Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Cell 124 (2006) 161-173
    • (2006) Cell , vol.124 , pp. 161-173
    • Foo, S.S.1
  • 57
    • 34249910664 scopus 로고    scopus 로고
    • PSGL-1-mediated activation of EphB4 increases the proangiogenic potential of endothelial progenitor cells
    • Foubert P., et al. PSGL-1-mediated activation of EphB4 increases the proangiogenic potential of endothelial progenitor cells. J. Clin. Invest. 117 (2007) 1527-1537
    • (2007) J. Clin. Invest. , vol.117 , pp. 1527-1537
    • Foubert, P.1
  • 58
    • 31044443483 scopus 로고    scopus 로고
    • Inhibition of retinal neovascularization by soluble EphA2 receptor
    • Chen J., et al. Inhibition of retinal neovascularization by soluble EphA2 receptor. Exp. Eye Res. 82 (2006) 664-673
    • (2006) Exp. Eye Res. , vol.82 , pp. 664-673
    • Chen, J.1
  • 59
    • 33751168256 scopus 로고    scopus 로고
    • EphB2 and EphB4 receptors forward signaling promotes SDF-1-induced endothelial cell chemotaxis and branching remodeling
    • Salvucci O., et al. EphB2 and EphB4 receptors forward signaling promotes SDF-1-induced endothelial cell chemotaxis and branching remodeling. Blood 108 (2006) 2914-2922
    • (2006) Blood , vol.108 , pp. 2914-2922
    • Salvucci, O.1
  • 60
    • 38149090292 scopus 로고    scopus 로고
    • The blood-brain barrier in health and chronic neurodegenerative disorders
    • Zlokovic B.V. The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 57 (2008) 178-201
    • (2008) Neuron , vol.57 , pp. 178-201
    • Zlokovic, B.V.1
  • 61
    • 29244463365 scopus 로고    scopus 로고
    • Astrocyte-endothelial interactions at the blood-brain barrier
    • Abbott N.J., et al. Astrocyte-endothelial interactions at the blood-brain barrier. Nat. Rev. Neurosci. 7 (2006) 41-53
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 41-53
    • Abbott, N.J.1
  • 62
    • 33747368249 scopus 로고    scopus 로고
    • Blood-brain barrier: structural components and function under physiologic and pathologic conditions
    • Persidsky Y., et al. Blood-brain barrier: structural components and function under physiologic and pathologic conditions. J. Neuroimmune. Pharmacol. 1 (2006) 223-236
    • (2006) J. Neuroimmune. Pharmacol. , vol.1 , pp. 223-236
    • Persidsky, Y.1
  • 63
    • 33748590788 scopus 로고    scopus 로고
    • Three distinct roles of aquaporin-4 in brain function revealed by knockout mice
    • Verkman A.S., et al. Three distinct roles of aquaporin-4 in brain function revealed by knockout mice. Biochim. Biophys. Acta 1758 (2006) 1085-1093
    • (2006) Biochim. Biophys. Acta , vol.1758 , pp. 1085-1093
    • Verkman, A.S.1
  • 64
    • 34447626102 scopus 로고    scopus 로고
    • Astrocytic calcium signaling: the information currency coupling neuronal activity to the cerebral microcirculation
    • Straub S.V., and Nelson M.T. Astrocytic calcium signaling: the information currency coupling neuronal activity to the cerebral microcirculation. Trends Cardiovasc. Med. 17 (2007) 183-190
    • (2007) Trends Cardiovasc. Med. , vol.17 , pp. 183-190
    • Straub, S.V.1    Nelson, M.T.2
  • 65
    • 49249138741 scopus 로고    scopus 로고
    • Tone-dependent vascular responses to astrocyte-derived signals
    • Blanco V.M., et al. Tone-dependent vascular responses to astrocyte-derived signals. Am. J. Physiol. Heart Circ. Physiol. 294 (2008) H2855-2863
    • (2008) Am. J. Physiol. Heart Circ. Physiol. , vol.294
    • Blanco, V.M.1
  • 66
    • 0141785164 scopus 로고    scopus 로고
    • A niche for adult neural stem cells
    • Doetsch F. A niche for adult neural stem cells. Curr. Opin. Genet. Dev. 13 (2003) 543-550
    • (2003) Curr. Opin. Genet. Dev. , vol.13 , pp. 543-550
    • Doetsch, F.1
  • 67
    • 0034597430 scopus 로고    scopus 로고
    • Vascular niche for adult hippocampal neurogenesis
    • Palmer T.D., et al. Vascular niche for adult hippocampal neurogenesis. J. Comp. Neurol. 425 (2000) 479-494
    • (2000) J. Comp. Neurol. , vol.425 , pp. 479-494
    • Palmer, T.D.1
  • 68
    • 0037194887 scopus 로고    scopus 로고
    • LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal
    • Capela A., and Temple S. LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal. Neuron 35 (2002) 865-875
    • (2002) Neuron , vol.35 , pp. 865-875
    • Capela, A.1    Temple, S.2
  • 69
    • 2542626091 scopus 로고    scopus 로고
    • Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells
    • Shen Q., et al. Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells. Science 304 (2004) 1338-1340
    • (2004) Science , vol.304 , pp. 1338-1340
    • Shen, Q.1
  • 70
    • 33344455016 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor is a niche signal for neural stem cell renewal
    • Ramirez-Castillejo C., et al. Pigment epithelium-derived factor is a niche signal for neural stem cell renewal. Nat. Neurosci. 9 (2006) 331-339
    • (2006) Nat. Neurosci. , vol.9 , pp. 331-339
    • Ramirez-Castillejo, C.1
  • 71
    • 46049118038 scopus 로고    scopus 로고
    • Neural progenitor cells treated with EPO induce angiogenesis through the production of VEGF
    • Wang L., et al. Neural progenitor cells treated with EPO induce angiogenesis through the production of VEGF. J. Cereb. Blood Flow. Metab. 28 (2008) 1361-1368
    • (2008) J. Cereb. Blood Flow. Metab. , vol.28 , pp. 1361-1368
    • Wang, L.1
  • 72
    • 30044451865 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-B (VEGF-B) stimulates neurogenesis: evidence from knockout mice and growth factor administration
    • Sun Y., et al. Vascular endothelial growth factor-B (VEGF-B) stimulates neurogenesis: evidence from knockout mice and growth factor administration. Dev. Biol. 289 (2006) 329-335
    • (2006) Dev. Biol. , vol.289 , pp. 329-335
    • Sun, Y.1
  • 73
    • 34548501737 scopus 로고    scopus 로고
    • Endogenous erythropoietin signaling is required for normal neural progenitor cell proliferation
    • Chen Z.Y., et al. Endogenous erythropoietin signaling is required for normal neural progenitor cell proliferation. J. Biol. Chem. 282 (2007) 25875-25883
    • (2007) J. Biol. Chem. , vol.282 , pp. 25875-25883
    • Chen, Z.Y.1
  • 74
    • 33845383924 scopus 로고    scopus 로고
    • Modeling the neurovascular niche: VEGF- and BDNF-mediated cross-talk between neural stem cells and endothelial cells: an in vitro study
    • Li Q., et al. Modeling the neurovascular niche: VEGF- and BDNF-mediated cross-talk between neural stem cells and endothelial cells: an in vitro study. J. Neurosci. Res. 84 (2006) 1656-1668
    • (2006) J. Neurosci. Res. , vol.84 , pp. 1656-1668
    • Li, Q.1
  • 75
    • 33644507720 scopus 로고    scopus 로고
    • Adult neurogenesis and functional plasticity in neuronal circuits
    • Lledo P.M., et al. Adult neurogenesis and functional plasticity in neuronal circuits. Nat. Rev. Neurosci. 7 (2006) 179-193
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 179-193
    • Lledo, P.M.1
  • 76
    • 58249113838 scopus 로고    scopus 로고
    • Micro-environment drives the endothelial or neural fate of differentiating embryonic stem cells coexpressing neuropilin-1 and Flk-1
    • Gualandris A., et al. Micro-environment drives the endothelial or neural fate of differentiating embryonic stem cells coexpressing neuropilin-1 and Flk-1. Faseb J. 23 (2009) 68-78
    • (2009) Faseb J. , vol.23 , pp. 68-78
    • Gualandris, A.1
  • 77
    • 34249803200 scopus 로고    scopus 로고
    • Blood vessels form a scaffold for neuroblast migration in the adult olfactory bulb
    • Bovetti S., et al. Blood vessels form a scaffold for neuroblast migration in the adult olfactory bulb. J. Neurosci. 27 (2007) 5976-5980
    • (2007) J. Neurosci. , vol.27 , pp. 5976-5980
    • Bovetti, S.1
  • 78
    • 65249118446 scopus 로고    scopus 로고
    • Vasculature guides migrating neuronal precursors in the adult mammalian forebrain via brain-derived neurotrophic factor signaling
    • Snapyan M., et al. Vasculature guides migrating neuronal precursors in the adult mammalian forebrain via brain-derived neurotrophic factor signaling. J. Neurosci. 29 (2009) 4172-4188
    • (2009) J. Neurosci. , vol.29 , pp. 4172-4188
    • Snapyan, M.1
  • 79
    • 0030694696 scopus 로고    scopus 로고
    • Interactions between glial progenitors and blood vessels during early postnatal corticogenesis: blood vessel contact represents an early stage of astrocyte differentiation
    • Zerlin M., and Goldman J.E. Interactions between glial progenitors and blood vessels during early postnatal corticogenesis: blood vessel contact represents an early stage of astrocyte differentiation. J. Comp. Neurol. 387 (1997) 537-546
    • (1997) J. Comp. Neurol. , vol.387 , pp. 537-546
    • Zerlin, M.1    Goldman, J.E.2
  • 80
    • 33646533333 scopus 로고    scopus 로고
    • Transplanted glioma cells migrate and proliferate on host brain vasculature: a dynamic analysis
    • Farin A., et al. Transplanted glioma cells migrate and proliferate on host brain vasculature: a dynamic analysis. Glia 53 (2006) 799-808
    • (2006) Glia , vol.53 , pp. 799-808
    • Farin, A.1
  • 81
    • 10344262577 scopus 로고    scopus 로고
    • The neurovascular unit and its growth factors: coordinated response in the vascular and nervous systems
    • Ward N.L., and Lamanna J.C. The neurovascular unit and its growth factors: coordinated response in the vascular and nervous systems. Neurol. Res. 26 (2004) 870-883
    • (2004) Neurol. Res. , vol.26 , pp. 870-883
    • Ward, N.L.1    Lamanna, J.C.2
  • 82
    • 64149125114 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-stimulated cerebral microvascular endothelial cells mediate the recruitment of neural stem cells to the neurovascular niche
    • Schmidt N.O., et al. Vascular endothelial growth factor-stimulated cerebral microvascular endothelial cells mediate the recruitment of neural stem cells to the neurovascular niche. Brain Res. 1268 (2009) 24-37
    • (2009) Brain Res. , vol.1268 , pp. 24-37
    • Schmidt, N.O.1
  • 83
    • 33845656103 scopus 로고    scopus 로고
    • A neurovascular niche for neurogenesis after stroke
    • Ohab J.J., et al. A neurovascular niche for neurogenesis after stroke. J. Neurosci. 26 (2006) 13007-13016
    • (2006) J. Neurosci. , vol.26 , pp. 13007-13016
    • Ohab, J.J.1
  • 84
    • 50249110037 scopus 로고    scopus 로고
    • Neural stem/progenitor cells promote endothelial cell morphogenesis and protect endothelial cells against ischemia via HIF-1alpha-regulated VEGF signaling
    • Roitbak T., et al. Neural stem/progenitor cells promote endothelial cell morphogenesis and protect endothelial cells against ischemia via HIF-1alpha-regulated VEGF signaling. J. Cereb. Blood Flow Metab. 28 (2008) 1530-1542
    • (2008) J. Cereb. Blood Flow Metab. , vol.28 , pp. 1530-1542
    • Roitbak, T.1
  • 85
    • 19944426191 scopus 로고    scopus 로고
    • Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway
    • Imitola J., et al. Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 18117-18122
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 18117-18122
    • Imitola, J.1
  • 86
    • 47249102905 scopus 로고    scopus 로고
    • Ephrins as negative regulators of adult neurogenesis in diverse regions of the central nervous system
    • Jiao J.W., et al. Ephrins as negative regulators of adult neurogenesis in diverse regions of the central nervous system. Proc. Natl. Acad Sci. U. S. A. 105 (2008) 8778-8783
    • (2008) Proc. Natl. Acad Sci. U. S. A. , vol.105 , pp. 8778-8783
    • Jiao, J.W.1
  • 88
    • 70349400563 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy: a common cause of cerebral hemorrhage
    • Pezzini A., et al. Cerebral amyloid angiopathy: a common cause of cerebral hemorrhage. Curr. Med. Chem. 16 (2009) 2498-2513
    • (2009) Curr. Med. Chem. , vol.16 , pp. 2498-2513
    • Pezzini, A.1
  • 89
    • 35349012675 scopus 로고    scopus 로고
    • Regulation of vascular morphogenesis by Notch signaling
    • Roca C., and Adams R.H. Regulation of vascular morphogenesis by Notch signaling. Genes Dev. 21 (2007) 2511-2524
    • (2007) Genes Dev. , vol.21 , pp. 2511-2524
    • Roca, C.1    Adams, R.H.2
  • 90
    • 43649105915 scopus 로고    scopus 로고
    • Alzheimer's disease, cerebrovascular dysfunction and the benefits of exercise: from vessels to neurons
    • Lange-Asschenfeldt C., and Kojda G. Alzheimer's disease, cerebrovascular dysfunction and the benefits of exercise: from vessels to neurons. Exp. Gerontol. 43 (2008) 499-504
    • (2008) Exp. Gerontol. , vol.43 , pp. 499-504
    • Lange-Asschenfeldt, C.1    Kojda, G.2
  • 91
    • 16644382257 scopus 로고    scopus 로고
    • Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS
    • Storkebaum E., et al. Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS. Nat. Neurosci. 8 (2005) 85-92
    • (2005) Nat. Neurosci. , vol.8 , pp. 85-92
    • Storkebaum, E.1
  • 92
    • 77953732352 scopus 로고    scopus 로고
    • VEGF protects motor neurons against excitotoxicity by upregulation of GluR2
    • in press doi:10.1016/j.neurobiolaging.2008.12.007
    • Bogaert, E. et al. (2009) VEGF protects motor neurons against excitotoxicity by upregulation of GluR2. Neurobiol Aging (in press) doi:10.1016/j.neurobiolaging.2008.12.007
    • (2009) Neurobiol Aging
    • Bogaert, E.1
  • 93
    • 54849424014 scopus 로고    scopus 로고
    • Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration
    • Poesen K., et al. Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration. J. Neurosci. 28 (2008) 10451-10459
    • (2008) J. Neurosci. , vol.28 , pp. 10451-10459
    • Poesen, K.1
  • 94
    • 33645422711 scopus 로고    scopus 로고
    • ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis
    • Greenway M.J., et al. ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis. Nat. Genet. 38 (2006) 411-413
    • (2006) Nat. Genet. , vol.38 , pp. 411-413
    • Greenway, M.J.1
  • 95
    • 2642526164 scopus 로고    scopus 로고
    • VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model
    • Azzouz M., et al. VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model. Nature 429 (2004) 413-417
    • (2004) Nature , vol.429 , pp. 413-417
    • Azzouz, M.1
  • 96
    • 70350167840 scopus 로고    scopus 로고
    • Intrathecal transplantation of human neural stem cells overexpressing VEGF provide behavioral improvement, disease onset delay and survival extension in transgenic ALS mice
    • in press doi:10.1038/gt.2009.80
    • Hwang, D.H. et al. (2009) Intrathecal transplantation of human neural stem cells overexpressing VEGF provide behavioral improvement, disease onset delay and survival extension in transgenic ALS mice. Gene Ther (in press) doi:10.1038/gt.2009.80
    • (2009) Gene Ther
    • Hwang, D.H.1
  • 97
    • 34250624892 scopus 로고    scopus 로고
    • Favorable effects of VEGF gene transfer on a rat model of Parkinson's disease using adeno-associated viral vectors
    • Tian Y.Y., et al. Favorable effects of VEGF gene transfer on a rat model of Parkinson's disease using adeno-associated viral vectors. Neurosci. Lett. 421 (2007) 239-244
    • (2007) Neurosci. Lett. , vol.421 , pp. 239-244
    • Tian, Y.Y.1
  • 98
    • 17144474840 scopus 로고    scopus 로고
    • Favorable effect of VEGF gene transfer on ischemic peripheral neuropathy
    • Schratzberger P., et al. Favorable effect of VEGF gene transfer on ischemic peripheral neuropathy. Nat. Med. 6 (2000) 405-413
    • (2000) Nat. Med. , vol.6 , pp. 405-413
    • Schratzberger, P.1
  • 99
    • 33745277087 scopus 로고    scopus 로고
    • VEGF 164 gene transfer by electroporation improves diabetic sensory neuropathy in mice
    • Murakami T., et al. VEGF 164 gene transfer by electroporation improves diabetic sensory neuropathy in mice. J. Gene Med. 8 (2006) 773-781
    • (2006) J. Gene Med. , vol.8 , pp. 773-781
    • Murakami, T.1
  • 100
    • 65649114702 scopus 로고    scopus 로고
    • Vascular endothelial growth factor gene transfer for diabetic polyneuropathy: a randomized, double-blinded trial
    • Ropper A.H., et al. Vascular endothelial growth factor gene transfer for diabetic polyneuropathy: a randomized, double-blinded trial. Ann. Neurol. 65 (2009) 386-393
    • (2009) Ann. Neurol. , vol.65 , pp. 386-393
    • Ropper, A.H.1
  • 101
    • 33745001464 scopus 로고    scopus 로고
    • Persistent production of neurons from adult brain stem cells during recovery after stroke
    • Thored P., et al. Persistent production of neurons from adult brain stem cells during recovery after stroke. Stem Cells 24 (2006) 739-747
    • (2006) Stem Cells , vol.24 , pp. 739-747
    • Thored, P.1
  • 102
    • 1442354188 scopus 로고    scopus 로고
    • Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration
    • Sanai N., et al. Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration. Nature 427 (2004) 740-744
    • (2004) Nature , vol.427 , pp. 740-744
    • Sanai, N.1
  • 103
    • 37349121771 scopus 로고    scopus 로고
    • Stem cells and neurological diseases
    • Hess D.C., and Borlongan C.V. Stem cells and neurological diseases. Cell Prolif. 41 Suppl 1 (2008) 94-114
    • (2008) Cell Prolif. , vol.41 , Issue.SUPPL. 1 , pp. 94-114
    • Hess, D.C.1    Borlongan, C.V.2
  • 104
    • 30744477950 scopus 로고    scopus 로고
    • From angiogenesis to neuropathology
    • Greenberg D.A., and Jin K. From angiogenesis to neuropathology. Nature 438 (2005) 954-959
    • (2005) Nature , vol.438 , pp. 954-959
    • Greenberg, D.A.1    Jin, K.2
  • 105
    • 30744479430 scopus 로고    scopus 로고
    • Angiogenesis in life, disease and medicine
    • Carmeliet P. Angiogenesis in life, disease and medicine. Nature 438 (2005) 932-936
    • (2005) Nature , vol.438 , pp. 932-936
    • Carmeliet, P.1
  • 106
    • 34547702738 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury
    • Nishijima K., et al. Vascular endothelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury. Am. J. Pathol. 171 (2007) 53-67
    • (2007) Am. J. Pathol. , vol.171 , pp. 53-67
    • Nishijima, K.1
  • 107
    • 40549090548 scopus 로고    scopus 로고
    • VEGF-B inhibits apoptosis via VEGFR-1-mediated suppression of the expression of BH3-only protein genes in mice and rats
    • Li Y., et al. VEGF-B inhibits apoptosis via VEGFR-1-mediated suppression of the expression of BH3-only protein genes in mice and rats. J. Clin. Invest. 118 (2008) 913-923
    • (2008) J. Clin. Invest. , vol.118 , pp. 913-923
    • Li, Y.1
  • 108
    • 33845313345 scopus 로고    scopus 로고
    • The clinical toxicity profile of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) targeting angiogenesis inhibitors; a review
    • Eskens F.A., and Verweij J. The clinical toxicity profile of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) targeting angiogenesis inhibitors; a review. Eur. J. Cancer 42 (2006) 3127-3139
    • (2006) Eur. J. Cancer , vol.42 , pp. 3127-3139
    • Eskens, F.A.1    Verweij, J.2
  • 109
    • 60649116477 scopus 로고    scopus 로고
    • Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited
    • Loges S., et al. Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited. Cancer Cell 15 (2009) 167-170
    • (2009) Cancer Cell , vol.15 , pp. 167-170
    • Loges, S.1
  • 110
    • 67649200247 scopus 로고    scopus 로고
    • Anti-VEGF therapies for malignant glioma: treatment effects and escape mechanisms
    • Miletic H., et al. Anti-VEGF therapies for malignant glioma: treatment effects and escape mechanisms. Expert Opin. Ther .Targets 13 (2009) 455-468
    • (2009) Expert Opin. Ther .Targets , vol.13 , pp. 455-468
    • Miletic, H.1
  • 111
    • 35148888161 scopus 로고    scopus 로고
    • Life with oxygen
    • Semenza G.L. Life with oxygen. Science 318 (2007) 62-64
    • (2007) Science , vol.318 , pp. 62-64
    • Semenza, G.L.1
  • 112
    • 0030004485 scopus 로고    scopus 로고
    • Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
    • Ferrara N., et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380 6573 (1996) 439-442
    • (1996) Nature , vol.380 , Issue.6573 , pp. 439-442
    • Ferrara, N.1
  • 113
    • 0343920277 scopus 로고    scopus 로고
    • Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
    • Carmeliet P., et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380 6573 (1996) 435-439
    • (1996) Nature , vol.380 , Issue.6573 , pp. 435-439
    • Carmeliet, P.1
  • 114
    • 0034978562 scopus 로고    scopus 로고
    • Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
    • Oosthuyse B., et al. Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Nat Genet 28 2 (2001) 131-138
    • (2001) Nat Genet , vol.28 , Issue.2 , pp. 131-138
    • Oosthuyse, B.1
  • 115
    • 0029006696 scopus 로고
    • Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
    • Shalaby F., et al. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376 6535 (1995) 62-66
    • (1995) Nature , vol.376 , Issue.6535 , pp. 62-66
    • Shalaby, F.1
  • 116
    • 0029021660 scopus 로고
    • Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
    • Fong G.H., et al. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376 6535 (1995) 66-70
    • (1995) Nature , vol.376 , Issue.6535 , pp. 66-70
    • Fong, G.H.1
  • 117
    • 0032764427 scopus 로고    scopus 로고
    • Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice
    • Fong G.H., et al. Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice. Development 126 13 (1999) 3015-3025
    • (1999) Development , vol.126 , Issue.13 , pp. 3015-3025
    • Fong, G.H.1
  • 118
    • 0030778454 scopus 로고    scopus 로고
    • Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice
    • Kitsukawa T., et al. Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice. Neuron 19 5 (1997) 995-1005
    • (1997) Neuron , vol.19 , Issue.5 , pp. 995-1005
    • Kitsukawa, T.1
  • 119
    • 0032707249 scopus 로고    scopus 로고
    • A requirement for neuropilin-1 in embryonic vessel formation
    • Kawasaki T., et al. A requirement for neuropilin-1 in embryonic vessel formation. Development 126 21 (1999) 4895-4902
    • (1999) Development , vol.126 , Issue.21 , pp. 4895-4902
    • Kawasaki, T.1
  • 120
    • 0034023548 scopus 로고    scopus 로고
    • Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections
    • Chen H., et al. Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections. Neuron 25 1 (2000) 43-56
    • (2000) Neuron , vol.25 , Issue.1 , pp. 43-56
    • Chen, H.1
  • 121
    • 0036803751 scopus 로고    scopus 로고
    • Abnormal lymphatic vessel development in neuropilin 2 mutant mice
    • Yuan L., et al. Abnormal lymphatic vessel development in neuropilin 2 mutant mice. Development 129 20 (2002) 4797-4806
    • (2002) Development , vol.129 , Issue.20 , pp. 4797-4806
    • Yuan, L.1
  • 122
    • 0029858256 scopus 로고    scopus 로고
    • Semaphorin III is needed for normal patterning and growth of nerves, bones and heart
    • Behar O., et al. Semaphorin III is needed for normal patterning and growth of nerves, bones and heart. Nature 383 6600 (1996) 525-528
    • (1996) Nature , vol.383 , Issue.6600 , pp. 525-528
    • Behar, O.1
  • 123
    • 0030987542 scopus 로고    scopus 로고
    • Disruption of semaphorin III/D gene causes severe abnormality in peripheral nerve projection
    • Taniguchi M., et al. Disruption of semaphorin III/D gene causes severe abnormality in peripheral nerve projection. Neuron 19 3 (1997) 519-530
    • (1997) Neuron , vol.19 , Issue.3 , pp. 519-530
    • Taniguchi, M.1
  • 124
    • 0041530325 scopus 로고    scopus 로고
    • Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function
    • Serini G., et al. Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function. Nature 424 6947 (2003) 391-397
    • (2003) Nature , vol.424 , Issue.6947 , pp. 391-397
    • Serini, G.1
  • 125
    • 34250662228 scopus 로고    scopus 로고
    • Selective requirements for NRP1 ligands during neurovascular patterning
    • Vieira J.M., Schwarz Q., and Ruhrberg C. Selective requirements for NRP1 ligands during neurovascular patterning. Development 134 10 (2007) 1833-1843
    • (2007) Development , vol.134 , Issue.10 , pp. 1833-1843
    • Vieira, J.M.1    Schwarz, Q.2    Ruhrberg, C.3
  • 126
    • 19944430075 scopus 로고    scopus 로고
    • Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins
    • Gu C., et al. Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins. Science 307 5707 (2005) 265-268
    • (2005) Science , vol.307 , Issue.5707 , pp. 265-268
    • Gu, C.1
  • 127
    • 4344594556 scopus 로고    scopus 로고
    • PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development
    • Gitler A.D., Lu M.M., and Epstein J.A. PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development. Dev Cell 7 1 (2004) 107-116
    • (2004) Dev Cell , vol.7 , Issue.1 , pp. 107-116
    • Gitler, A.D.1    Lu, M.M.2    Epstein, J.A.3
  • 128
    • 0030582772 scopus 로고    scopus 로고
    • Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system
    • Serafini T., et al. Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system. Cell 87 6 (1996) 1001-1014
    • (1996) Cell , vol.87 , Issue.6 , pp. 1001-1014
    • Serafini, T.1
  • 129
    • 0030995125 scopus 로고    scopus 로고
    • Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene
    • Fazeli A., et al. Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene. Nature 386 6627 (1997) 796-804
    • (1997) Nature , vol.386 , Issue.6627 , pp. 796-804
    • Fazeli, A.1
  • 130
    • 33747612460 scopus 로고    scopus 로고
    • UNC5A promotes neuronal apoptosis during spinal cord development independent of netrin-1
    • Williams M.E., et al. UNC5A promotes neuronal apoptosis during spinal cord development independent of netrin-1. Nat Neurosci 9 8 (2006) 996-998
    • (2006) Nat Neurosci , vol.9 , Issue.8 , pp. 996-998
    • Williams, M.E.1
  • 131
    • 8844281731 scopus 로고    scopus 로고
    • The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system
    • Lu X., et al. The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system. Nature 432 7014 (2004) 179-186
    • (2004) Nature , vol.432 , Issue.7014 , pp. 179-186
    • Lu, X.1
  • 132
    • 40949119773 scopus 로고    scopus 로고
    • The netrin receptor UNC5B promotes angiogenesis in specific vascular beds
    • Navankasattusas S., et al. The netrin receptor UNC5B promotes angiogenesis in specific vascular beds. Development 135 4 (2008) 659-667
    • (2008) Development , vol.135 , Issue.4 , pp. 659-667
    • Navankasattusas, S.1
  • 133
    • 3242704800 scopus 로고    scopus 로고
    • Conserved roles for Slit and Robo proteins in midline commissural axon guidance
    • Long H., et al. Conserved roles for Slit and Robo proteins in midline commissural axon guidance. Neuron 42 2 (2004) 213-223
    • (2004) Neuron , vol.42 , Issue.2 , pp. 213-223
    • Long, H.1
  • 134
    • 41849131420 scopus 로고    scopus 로고
    • Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability
    • Jones C.A., et al. Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability. Nat Med 14 4 (2008) 448-453
    • (2008) Nat Med , vol.14 , Issue.4 , pp. 448-453
    • Jones, C.A.1
  • 135
    • 0032577446 scopus 로고    scopus 로고
    • Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4
    • Wang H.U., Chen Z.F., and Anderson D.J. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 93 5 (1998) 741-753
    • (1998) Cell , vol.93 , Issue.5 , pp. 741-753
    • Wang, H.U.1    Chen, Z.F.2    Anderson, D.J.3
  • 136
    • 0033082959 scopus 로고    scopus 로고
    • Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis
    • Adams R.H., et al. Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Genes Dev 13 3 (1999) 295-306
    • (1999) Genes Dev , vol.13 , Issue.3 , pp. 295-306
    • Adams, R.H.1
  • 137
    • 0033197535 scopus 로고    scopus 로고
    • Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development
    • Gerety S.S., et al. Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development. Mol Cell 4 3 (1999) 403-414
    • (1999) Mol Cell , vol.4 , Issue.3 , pp. 403-414
    • Gerety, S.S.1
  • 138
    • 0033845946 scopus 로고    scopus 로고
    • Targeting of the EphA4 tyrosine kinase receptor affects dorsal/ventral pathfinding of limb motor axons
    • Helmbacher F., et al. Targeting of the EphA4 tyrosine kinase receptor affects dorsal/ventral pathfinding of limb motor axons. Development 127 15 (2000) 3313-3324
    • (2000) Development , vol.127 , Issue.15 , pp. 3313-3324
    • Helmbacher, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.