Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system

Cell

Volumn 87, Issue 6, 1996, Pages 1001-1014

  Serafini, Tito ^a,d   Colamarino, Sophia A ^a   Leonardo, E David ^a   Wang, Hao ^a   Beddington, Rosa ^b   Skarnes, William C ^c   Tessier Lavigne, Marc ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NETRIN 1; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; CELL MIGRATION; CONTROLLED STUDY; EMBRYO; IN SITU HYBRIDIZATION; MOUSE; NERVE FIBER GROWTH; NERVE PROJECTION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD; TROCHLEAR NERVE;

ANIMALIA; VERTEBRATA;

EID: 0030582772     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81795-X     Document Type: Article

References (28)

1. Bourrat, F., and Sotelo, C. (1990). Migratory pathways and selective aggregation of the lateral reticular neurons in the rat embryo: a horseradish peroxidase in vitro study, with special reference to migration patterns of the precerebellar nuclei. J. Comp. Neurol. 294, 1-13.
2. Colamarino, S.A., and Tessier-Lavigne, M. (1995a). The role of the floor plate in axon guidance. Annu. Rev. Neurosci. 18, 497-529.
3. Colamarino, S.A., and Tessier-Lavigne, M. (1995b). The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons. Cell 81, 621-629.
4. Culotti, J.G., and Kolodkin, A.L. (1996). Functions of netrins and semaphorins in axon guidance. Curr. Opin. Neurobiol. 6, 81-88.
5. Dodd, J., Morton, S.B., Karagogeos, D., Yamamoto, M., and Jessell, T.M. (1988). Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons. Neuron 1, 105-116.
6. Echelard, Y., Epstein, D.J., St.-Jacques, B., Shen, L., Mohler, J., McMahon, J.A., and McMahon, A.P. (1993). Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75, 1417-1430.
7. Fritzsch, B, Nichols, D.H., Echelard, Y., McMahon, A.P. (1995). Development of midbrain and anterior hindbrain ocular motoneurons in normal and Wnt-1 knockout mice. J. Neurobiol. 27, 457-469.
8. Harris, R., Sabatelli, L.M., and Seeger, M.A. (1996). Guidance cues at the Drosophila CNS midline: identification and characterization of two Drosophila Netrin/UNC-6 homologs. Neuron 17, 217-228.
9. Hedgecock, E.M., Culotti, J.G., and Hall, D.H. (1990). The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans. Neuron 2, 61-85.
10. Hu, H., and Rutishauser, U. (1996). A septum-derived chemorepulsive factor for migrating olfactory interneuron precursors. Neuron 16, 933-940.
11. Ishii, N., Wadsworth, W.G., Stern, B.D., Culotti, J.G., and Hedgecock, E.M. (1992). UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans. Neuron 9, 873-881.
12. Kennedy, T.E., Serafini, T., de la Torre, J.R., and Tessier-Lavigne, M. (1994). Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord. Cell 78, 425-435.
13. Klar, A., Baldassare, M., and Jessell, T.M. (1992). F-spondin: a gene expressed at high levels in the floor plate encodes a secreted protein that promotes neural cell adhesion and neurite extension. Cell 69, 95-110.
14. Mitchell, K.J., Doyle, J.L., Serafini, T., Kennedy, T., Tessier-Lavigne, M., Goodman, C.S., and Dickson, B.J. (1996). Genetic analysis of Netrin genes in Drosophila: Netrins guide CNS commissural axons and peripheral motor axons. Neuron 17, 203-215.
15. Placzek, M., Tessier-Lavigne, M., Jessell, T.M., and Dodd, J. (1990). Orientation of commissural axons in vitro in response to a floor plate-derived chemoattractant. Development 110, 19-30.
16. Probst, M. (1901). Über den Bau des balkenlosen Groβhirns, sowie über Mikrogyrie und Heterotypie der grauer Substanz. Arch. F. Psychiatr. 34, 709-786.
17. Ruiz i Altaba, A., Prezioso, V.R., Darnell, J.E., and Jessell, T.M. (1993). Sequential expression of HNF-3 beta and HNF-3 alpha by embryonic organizing centers: the dorsal lip/node, notochord and floor plate. Mech. Dev. 44, 91-108.
18. Sasaki, H., and Hogan, B.L. (1993). Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo. Development 118, 47-59.
19. Serafini, T., Kennedy, T.E., Galko, M.J., Mirzayan, C., Jessell, T.M., and Tessier-Lavigne, M. (1994). The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6. Cell 78, 409-424.
20. Shirasaki, R., Tamada, A., Katsumata, R., and Murakami, F. (1995). Guidance of cerebellofugal axons in the rat embryo: directed growth toward the floor plate and subsequent elongation along the longitudinal axis. Neuron 14, 961-972.
21. Silver, J., Edwards, M.A., and Levitt, P. (1993). Immunocytochemical demonstration of early appearing astroglial structures that form boundaries and pathways along axon tracts in the fetal brain. J. Comp. Neurol. 328, 415-436.
22. Skarnes, W.C., Moss, J.E., Hurtley, S.M., and Beddington, R.S.P. (1995). Capturing genes encoding membrane and secreted proteins important for mouse development. Proc. Natl. Acad. Sci. USA 92, 6592-6596.
23. Tanabe, Y., Roelink, H., and Jessell, T.M. (1995). Induction of motor neurons by Sonic hedgehog is independent of floor plate differentiation. Curr. Biol. 5, 651-658.
24. Tessier-Lavigne, M., and Goodman, C.S. (1996). The molecular biology of axon guidance. Science, in press.
25. Tessier-Lavigne, M., Placzek, M., Lumsden, A.G.S., Dodd, J., and Jessell, T.M. (1988). Chemotropic guidance of developing axons in the mammalian central nervous system. Nature 336, 775-778.
26. Thomas, K.R., and Capecchi, M.R. (1987). Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51, 503-512.
27. Wadsworth, W.G., Bhatt, H., and Hedgecock, E.M. (1996). Neuroglia and pioneer neurons express UNC-6 to provide global and local netrin cues for guiding migrations in C. elegans. Neuron 16, 35-46.
28. Wentworth, L.E. (1984). The development of the cervical spinal cord of the mouse embryo. II. A Golgi analysis of sensory, commissural, and association cell differentiation. J. Comp. Neurol. 222, 96-115.