Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability

Nature Medicine

Volumn 14, Issue 4, 2008, Pages 448-453

  Jones, Christopher A ^a   London, Nyall R ^a   Chen, Haoyu ^a   Park, Kye Won ^a,f   Sauvaget, Dominique ^b   Stockton, Rebecca A ^a   Wythe, Joshua D ^a   Suh, Wonhee ^a,g   Larrieu Lahargue, Frederic ^a   Mukouyama, Yoh Suke ^d   Lindblom, Per ^b,i   Seth, Pankaj ^e   Frias, Antonio ^a   Nishiya, Naoyuki ^c,h   Ginsberg, Mark H ^c   Gerhardt, Holger ^b   Zhang, Kang ^a   Li, Dean Y ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g Samsung Medical Center   (South Korea)

^h IWATE MEDICAL UNIVERSITY   (Japan)

ⁱ ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE; ROUNDABOUT RECEPTOR; ROUNDABOUT RECEPTOR 4; SLIT2 PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN 165;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL MIGRATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENE DELETION; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STABILITY; RETINA NEOVASCULARIZATION; SUBRETINAL NEOVASCULARIZATION; VASCULAR ENDOTHELIUM;

ANIMALS; CAPILLARY PERMEABILITY; CHOROID; ENDOTHELIUM, VASCULAR; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NEOVASCULARIZATION, PATHOLOGIC; NERVE TISSUE PROTEINS; RECEPTORS, IMMUNOLOGIC; RECOMBINANT PROTEINS; RETINAL VESSELS; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

MAMMALIA;

EID: 41849131420     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1742     Document Type: Article

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