Knockout mice lacking cPGES/p23, a constitutively expressed PGE2 synthetic enzyme, are peri-natally lethal

Biochemical and Biophysical Research Communications

Volumn 362, Issue 2, 2007, Pages 387-392

  Nakatani, Yoshihito ^a   Hokonohara, Yutaka ^a   Kakuta, Shigeru ^b   Sudo, Katsuko ^b   Iwakura, Yoichiro ^b   Kudo, Ichiro ^a  

^a SHOWA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Cytosolic prostaglandin E synthase; Embryonic lethality; Knockout mouse; Lung development; Prostaglandin E2

Indexed keywords

HEAT SHOCK PROTEIN 90; MUTANT PROTEIN; PROSTAGLANDIN E SYNTHASE; PROSTAGLANDIN E2; TYROSINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CATALYSIS; CELL STRUCTURE; CONTROLLED STUDY; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; EXON; FERTILITY; GENE CONTROL; GENE DISRUPTION; GROWTH RETARDATION; HETEROZYGOSITY; HOMOZYGOSITY; IN VIVO STUDY; LETHALITY; LUNG ALVEOLUS CELL; MORTALITY; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; SKIN CELL;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; BRAIN; DINOPROSTONE; EMBRYONIC STRUCTURES; FEMALE; FETAL GROWTH RETARDATION; FETAL HEART; GENES, LETHAL; GENOTYPE; INTRAMOLECULAR OXIDOREDUCTASES; LIVER; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; SKIN;

MUS;

EID: 34548281074     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.07.180     Document Type: Article

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